Article ; Online: Clinical management of patients with genetic obesity during COVID-19 pandemic: position paper of the ESE Growth & Genetic Obesity COVID-19 Study Group and Rare Endo-ERN main thematic group on Growth and Obesity.
2021 Volume 71, Issue 3, Page(s) 653–662
Abstract: ... with genetic obesity. Key principals of the management of patients with genetic obesity during COVID-19 ... infection, even in case of obesity. Key principals of the obesity management during the pandemic are ... pandemic for patients that have contracted COVID-19 are to be aware of: possible adrenal insufficiency (e.g ...
| Abstract | This article aims to provide guidance on prevention and treatment of COVID-19 in patients with genetic obesity. Key principals of the management of patients with genetic obesity during COVID-19 pandemic for patients that have contracted COVID-19 are to be aware of: possible adrenal insufficiency (e.g., POMC deficiency, PWS); a more severe course in patients with concomitant immunodeficiency (e.g., LEP and LEPR deficiency), although defective leptin signalling could also be protective against the pro-inflammatory phenotype of COVID-19; disease severity being masked by insufficient awareness of symptoms in syndromic obesity patients with intellectual deficit (in particular PWS); to adjust medication dose to increased body size, preferably use dosing in m2; the high risk of malnutrition in patients with Sars-Cov2 infection, even in case of obesity. Key principals of the obesity management during the pandemic are to strive for optimal obesity management and a healthy lifestyle within the possibilities of the regulations to prevent weight (re)gain and to address anxiety within consultations, since prevalence of anxiety for COVID-19 is underestimated. |
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| MeSH term(s) | Anxiety ; COVID-19 ; Disease Management ; Healthy Lifestyle ; Humans ; Obesity/epidemiology ; Obesity/genetics ; Obesity/therapy ; Pandemics | |||||
| Language | English | |||||
| Publishing date | 2021-01-29 | |||||
| Publishing country | United States | |||||
| Document type | Journal Article ; Research Support, Non-U.S. Gov't ; Review | |||||
| ZDB-ID | 1194484-5 | |||||
| ISSN | 1559-0100 ; 1355-008X ; 0969-711X | |||||
| ISSN (online) | 1559-0100 | |||||
| ISSN | 1355-008X ; 0969-711X | |||||
| DOI | 10.1007/s12020-021-02619-y | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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