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Article ; Online: Unilateral Optic Neuritis Associated with SARS-CoV-2 Infection: A Rare Complication.

Deane, Kitson / Sarfraz, Azza / Sarfraz, Zouina / Valentine, Dhiviyan / Idowu, Abidemi Rachael / Sanchez, Vincent

The American journal of case reports

2021  Volume 22, Page(s) e931665

Abstract: ... an association between our patient's optic neuritis and her infection with SARS-CoV-2. CASE REPORT A 21-year-old ... an uncommon complication of SARS-CoV-2. This rather rare complication of SARS-CoV-2 is one that clinicians ... we describe a case of optic neuritis in a female patient concurrently infected with SARS-CoV-2 ...

Abstract BACKGROUND Since the outbreak of the SARS-CoV-2 infection, extensive research has been conducted on the pulmonary implications of this novel disease. However, there has been limited data on the extrapulmonary manifestations. There have been few documented causes of optic involvement and little is understood about the pathophysiology around its presentation and the possible treatments to prevent long-term complications. Here, we describe a case of optic neuritis in a female patient concurrently infected with SARS-CoV-2. Given the plethora of evidence supporting neurological manifestations of the virus, we hypothesize that there is an association between our patient's optic neuritis and her infection with SARS-CoV-2. CASE REPORT A 21-year-old woman with no past medical history who presented with blurry vision in her left eye. Optic neuritis was suspected with physical examination and confirmed with imaging of the optic nerve. Further diagnostic evaluation was nonsuggestive of multiple sclerosis and other demyelinating diseases; however, the patient was found to be positive for SARS-CoV-2. Steroids and remdesivir treatment were started, but without the presence of any respiratory symptoms. The patient's symptoms completely resolved by day 5 of hospitalization and she was discharged home without any complications. CONCLUSIONS Optic neuritis has remained an uncommon complication of SARS-CoV-2. This rather rare complication of SARS-CoV-2 is one that clinicians should be cognizant of due to the long-term implications of optic neuritis. Furthermore, it is pertinent to consider ophthalmic involvement in SARS-CoV-2 infection to appropriately guide patient care during the pandemic, as prompt treatment can lead to improved outcomes.
MeSH term(s) Adult ; COVID-19 ; Female ; Humans ; Multiple Sclerosis ; Optic Neuritis/diagnosis ; Optic Neuritis/etiology ; Pandemics ; SARS-CoV-2 ; Young Adult
Language English
Publishing date 2021-06-13
Publishing country United States
Document type Case Reports ; Journal Article
ZDB-ID 2517183-5
ISSN 1941-5923 ; 1941-5923
ISSN (online) 1941-5923
ISSN 1941-5923
DOI 10.12659/AJCR.931665
Database MEDical Literature Analysis and Retrieval System OnLINE

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