Article ; Online: Neurological manifestations of coronavirus disease 2019: exploring past to understand present.
2021 Volume 42, Issue 3, Page(s) 773–785
Abstract: SARS-CoV-2 infection, resulting in Coronavirus disease 2019 (COVID-19), has significantly affected ... Interestingly, many COVID-19 cases may present with pure neurological manifestations at onset with non ... respiratory symptoms, neurological features have been described. Neurological manifestations may vary from non ...
Abstract | SARS-CoV-2 infection, resulting in Coronavirus disease 2019 (COVID-19), has significantly affected the entire world. It was labelled a pandemic by World Health Organization. Although it commonly produces respiratory symptoms, neurological features have been described. Neurological manifestations may vary from non-specific symptoms such as headache, dizziness, myalgia and/or fatigue, olfactory or taste dysfunction to specific syndromes including meningitis, stroke, acute transverse myelitis and Guillain-Barre syndrome. This review describes potential pathogenetic mechanisms and neurological manifestations of COVID-19 along with its management. Considering structural and pathogenetic similarity of SARS-CoV-2 with SARS-CoV and MERS viruses, we compared their neurological manifestations and mentioned few features expected in COVID-19 in future. Interestingly, many COVID-19 cases may present with pure neurological manifestations at onset with non-neurological features manifesting few days later and we propose the term "Neuro-COVID syndrome" for such cases. Awareness of neurological manifestations may facilitate its management and improve outcome in such patients. |
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MeSH term(s) | COVID-19/complications ; Coronavirus Infections/complications ; Humans ; Nervous System Diseases/virology ; SARS-CoV-2 ; Severe Acute Respiratory Syndrome/complications | |||||
Language | English | |||||
Publishing date | 2021-01-11 | |||||
Publishing country | Italy | |||||
Document type | Journal Article ; Review | |||||
ZDB-ID | 2016546-8 | |||||
ISSN | 1590-3478 ; 1590-1874 | |||||
ISSN (online) | 1590-3478 | |||||
ISSN | 1590-1874 | |||||
DOI | 10.1007/s10072-020-04964-8 | |||||
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Database | MEDical Literature Analysis and Retrieval System OnLINE |
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