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  1. Article ; Online: COVID-19 guidelines for pregnant women and new mothers: A systematic evidence review.

    DiLorenzo, Madeline A / O'Connor, Sarah K / Ezekwesili, Caroline / Sampath, Spoorthi / Zhao, Molly / Yarrington, Christina / Pierre, Cassandra

    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

    2021  Volume 153, Issue 3, Page(s) 373–382

    Abstract: Background: Nearly a year after COVID-19 was initially detected, guidance for pregnant and new ... mothers remains varied.: Objective: The goal of this systematic review is to summarize recommendations ... 2020.: Selection criteria: Articles were included if they focused on COVID-positive mothers ...

    Abstract Background: Nearly a year after COVID-19 was initially detected, guidance for pregnant and new mothers remains varied.
    Objective: The goal of this systematic review is to summarize recommendations for three areas of maternal and fetal care-breastfeeding, post-partum social distancing, and decontamination.
    Search strategy: We searched PubMed, Embase and Web of Science spanning from inception to November 9, 2020.
    Selection criteria: Articles were included if they focused on COVID-positive mothers, commented on at least one of the three areas of interest, and were published in English.
    Data collection and analysis: Our combined database search yielded 385 articles. After removing duplicates and articles that did not cover the correct populations or subject matter, a total of 74 articles remained in our analysis.
    Main results: Most articles recommended direct breastfeeding with enhanced precaution measures. Recommendations regarding post-partum social distancing varied, although articles published more recently often recommended keeping the mother and newborn in the same room when possible. Decontamination recommendations emphasized mask wearing, good hand hygiene, and proper cleaning of surfaces.
    Conclusion: In general, there was a focus on shared decision making when approaching topics such as breastfeeding and post-partum social distancing. Guidelines for decontamination were fairly uniform.
    MeSH term(s) Breast Feeding ; COVID-19/prevention & control ; Female ; Guidelines as Topic ; Humans ; Infant, Newborn ; Infection Control/methods ; Mothers/education ; Physical Distancing ; Postpartum Period ; Pregnancy ; Pregnant Women/education ; SARS-CoV-2
    Language English
    Publishing date 2021-03-29
    Publishing country United States
    Document type Journal Article ; Systematic Review
    ZDB-ID 80149-5
    ISSN 1879-3479 ; 0020-7292
    ISSN (online) 1879-3479
    ISSN 0020-7292
    DOI 10.1002/ijgo.13668
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Effect of COVID-19 on Pregnancy and Neonate's Vital Parameters: A Systematic Review.

    Charuta, Anna / Smuniewska, Monika / Woźniak, Zofia / Paziewska, Agnieszka

    Journal of pregnancy

    2023  Volume 2023, Page(s) 3015072

    Abstract: ... for pregnant women, labour, and neonates born to infected mothers. The aim of this paper was to gather the evidence ... and to present a summary of the results of studies concerning COVID-19 in pregnant women and ... observed, although isolated cases of death related to COVID-19 in pregnant women were reported ...

    Abstract Background: COVID-19 is a new pandemic, which was declared by the World Health Organization in 2019 as a threat to public health. According to numerous reports, it can have negative consequences for pregnant women, labour, and neonates born to infected mothers. The aim of this paper was to gather the evidence and to present a summary of the results of studies concerning COVID-19 in pregnant women and their neonates.
    Methods: Articles from prestigious journals covering the period from 2020 to February 2023, relevant review papers, and original research articles from PubMed were analysed. In order to analyse the available research literature, the Web of Science, Scopus, and PubMed databases were used, in which the search for articles was conducted using terms ("pregnancy," "coronavirus," "SARS-CoV-2," and "newborn") and using PRISMA (Preferred Reporting Items for Systemic Reviews and Meta-Analysis) guidelines for clinical trials. Meta-analyses and systematic reviews (2022-2023) on symptoms, neonatal course, and risk of COVID-19 infection have been summarized. Summary of meta-analyses and systematic reviews (2022-2023) on the effect and adverse reaction of the COVID-19 vaccination is presented.
    Results: As a result of the research conducted, it was confirmed that in most pregnant women, no serious signs of the infection were observed, although isolated cases of death related to COVID-19 in pregnant women were reported. Several authors called attention to the more severe course of the infection in pregnant women with obesity. It seemed that no vertical transmission from mother to child was occurring. Nevertheless, the information was not clinching. The condition of the neonates born to mothers with COVID-19 was in most cases described as normal; however, some papers reported deaths of infected neonates.
    Conclusions: Due to insufficient data, further research is necessary. Further studies and follow-up are recommended, which would make possible an assessment of remote effects of COVID-19 on pregnancy and vital parameters of the newborn.
    MeSH term(s) Child ; Female ; Humans ; Infant, Newborn ; Pregnancy ; COVID-19 ; COVID-19 Vaccines ; Infectious Disease Transmission, Vertical/prevention & control ; Parturition ; Pregnancy Complications, Infectious/epidemiology ; Pregnancy Complications, Infectious/diagnosis ; SARS-CoV-2
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2023-05-13
    Publishing country Egypt
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 2595413-1
    ISSN 2090-2735 ; 2090-2735
    ISSN (online) 2090-2735
    ISSN 2090-2735
    DOI 10.1155/2023/3015072
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The Effects of COVID-19 Vaccination on Lactating Women: A Systematic Review of the Literature.

    Muyldermans, Joke / De Weerdt, Louise / De Brabandere, Larissa / Maertens, Kirsten / Tommelein, Eline

    Frontiers in immunology

    2022  Volume 13, Page(s) 852928

    Abstract: ... evidence that the administration of a COVID-19 vaccine is safe and poses no additional risk ... vaccination on lactating women.: Design: Systematic review.: Data sources: We searched Ovid Embase ... government health authorities should therefore recommend offering COVID-19 vaccines to breastfeeding women ...

    Abstract Objectives: The availability of new vaccines against COVID-19 urges for guidance about vaccination during lactation. We aimed to review the literature to get an insight into the effects of COVID-19 vaccination on lactating women.
    Design: Systematic review.
    Data sources: We searched Ovid Embase Classic+Embase, PubMed and BioMed Central for articles published between December 1
    Review methods: The search strategy contained terms and combinations related to COVID-19 vaccination during lactation, including the MeSH terms "COVID-19", "COVID-19 Vaccines", "SARS-CoV-2", "Lactation", "Breast Feeding", "Pregnancy" and "Postpartum period". The database search was completed with a manual search of the reference lists of included articles. Data concerning country, study period, number of participants, type of applied vaccine, time points of sampling and outcome measures were collected from the selected manuscripts. The data are summarized and synthesized in a descriptive way.
    Results: 30 manuscripts were included in this review. Data on safety of COVID-19 vaccination during lactation indicate no severe vaccine-related local and systemic reactions, both after first and second dose, neither in the mother nor the nursing child. No significant amount of vaccine components seems to appear in breast milk. Milk supply data after vaccination are inconclusive as there are no quantitative data available. Some women however observe a temporary increase or reduction in milk supply, without long-term effects. All prospective cohort studies demonstrated the presence of SARS-CoV-2-specific antibodies in breast milk of nursing mothers vaccinated against SARS-CoV-2. Nearly all studies were conducted with mRNA vaccines.
    Conclusion: There is evidence that the administration of a COVID-19 vaccine is safe and poses no additional risk to the breastfeeding woman or the breastfed baby. After vaccination of the mother during the lactation period, antibodies appear in the milk, which could protect the infant against COVID-19. Professional associations and government health authorities should therefore recommend offering COVID-19 vaccines to breastfeeding women, as the potential benefits of maternal vaccination while breastfeeding outweigh the risks.
    MeSH term(s) Antibodies, Viral ; Breast Feeding ; COVID-19/prevention & control ; COVID-19 Vaccines/adverse effects ; Female ; Humans ; Infant ; Lactation ; Mothers ; Prospective Studies ; SARS-CoV-2 ; Vaccination
    Chemical Substances Antibodies, Viral ; COVID-19 Vaccines
    Language English
    Publishing date 2022-04-08
    Publishing country Switzerland
    Document type Systematic Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2022.852928
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A Review on Mode of Delivery during COVID-19 between December 2019 and April 2020.

    Debrabandere, Margot L / Farabaugh, Dana C / Giordano, Carolyn

    American journal of perinatology

    2020  Volume 38, Issue 4, Page(s) 332–341

    Abstract: ... in pregnant women with coronavirus disease 2019 (COVID-19) and the indications reported for cesarean section early ... in an increased rate of cesarean delivery for SARS-CoV-2 positive pregnant women.. · COVID-19 is a commonly ... vaginal delivery, cesarean section, vertical transmission, management, and guidelines. Peer-reviewed ...

    Abstract Objective: This study aims to review the published literature to determine mode of delivery in pregnant women with coronavirus disease 2019 (COVID-19) and the indications reported for cesarean section early in the pandemic to add information to the current narrative and raise awareness of trends discovered.
    Study design: A systematic review was conducted by searching PubMed, Scopus, and ScienceDirect databases for articles published between December 2019 and April 29, 2020 using a combination of the keywords such as COVID-19, coronavirus 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), pregnancy, vaginal delivery, cesarean section, vertical transmission, management, and guidelines. Peer-reviewed case studies with confirmed SARS-CoV-2 women who delivered were included to determine mode of delivery, indications for cesarean section, and maternal and neonatal characteristics.
    Results: A review of 36 total articles revealed deliveries in 203 SARS-CoV-2 positive pregnant women. A comparable severity of disease in pregnant versus nonpregnant women was noted, as previously determined. Overall, 68.9% of women delivered via cesarean section, with COVID-19 status alone being a common indication. Maternal COVID-19 may also be associated with increased risk of preterm labor, although neonatal outcomes were generally favorable. Despite eight of 206 newborns testing positive for SARS-CoV-2, there remains no definitive evidence of vertical transmission.
    Conclusion: COVID-19 status alone became a common indication for cesarean delivery early in the pandemic, despite lack of evidence for vertical transmission. The increase in cesarean rate in this data may reflect obstetricians attempting to serve their patients in the best way possible given the current climate of constantly evolving guidelines on safest mode of delivery for the mother, infant, and provider. Upholding current recommendations from trusted organizations as new data are published, while also providing individualized support to expecting mothers on most appropriate mode of delivery, will reduce the amount of unnecessary, unplanned cesarean sections and could lessen the psychological impact of delivering during the COVID-19 pandemic.
    Key points: · COVID-19 may result in an increased rate of cesarean delivery for SARS-CoV-2 positive pregnant women.. · COVID-19 is a commonly reported indication for cesarean section, despite management guidelines urging against this.. · Although eight neonates tested positive for SARS-CoV-2, all additional fluid and tissue samples tested negative..
    MeSH term(s) COVID-19/epidemiology ; COVID-19/prevention & control ; Cesarean Section/methods ; Cesarean Section/statistics & numerical data ; Delivery, Obstetric/methods ; Delivery, Obstetric/statistics & numerical data ; Female ; Humans ; Infant, Newborn ; Infectious Disease Transmission, Vertical/prevention & control ; Pregnancy ; Pregnancy Complications, Infectious/epidemiology ; Pregnancy Complications, Infectious/prevention & control ; Pregnancy Outcome ; SARS-CoV-2
    Language English
    Publishing date 2020-12-07
    Publishing country United States
    Document type Journal Article ; Systematic Review
    ZDB-ID 605671-4
    ISSN 1098-8785 ; 0735-1631
    ISSN (online) 1098-8785
    ISSN 0735-1631
    DOI 10.1055/s-0040-1721658
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: A Review on Mode of Delivery during COVID-19 between December 2019 and April 2020

    Debrabandere, Margot L. / Farabaugh, Dana C. / Giordano, Carolyn

    American Journal of Perinatology

    2020  Volume 38, Issue 04, Page(s) 332–341

    Abstract: ... in pregnant women with coronavirus disease 2019 (COVID-19) and the indications reported for cesarean section early ... in an increased rate of cesarean delivery for SARS-CoV-2 positive pregnant women. COVID-19 is a commonly reported ... vaginal delivery, cesarean section, vertical transmission, management, and guidelines. Peer-reviewed ...

    Abstract Objective: This study aims to review the published literature to determine mode of delivery in pregnant women with coronavirus disease 2019 (COVID-19) and the indications reported for cesarean section early in the pandemic to add information to the current narrative and raise awareness of trends discovered.
    Study Design: A systematic review was conducted by searching PubMed, Scopus, and ScienceDirect databases for articles published between December 2019 and April 29, 2020 using a combination of the keywords such as COVID-19, coronavirus 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), pregnancy, vaginal delivery, cesarean section, vertical transmission, management, and guidelines. Peer-reviewed case studies with confirmed SARS-CoV-2 women who delivered were included to determine mode of delivery, indications for cesarean section, and maternal and neonatal characteristics.
    Results: A review of 36 total articles revealed deliveries in 203 SARS-CoV-2 positive pregnant women. A comparable severity of disease in pregnant versus nonpregnant women was noted, as previously determined. Overall, 68.9% of women delivered via cesarean section, with COVID-19 status alone being a common indication. Maternal COVID-19 may also be associated with increased risk of preterm labor, although neonatal outcomes were generally favorable. Despite eight of 206 newborns testing positive for SARS-CoV-2, there remains no definitive evidence of vertical transmission.
    Conclusion: COVID-19 status alone became a common indication for cesarean delivery early in the pandemic, despite lack of evidence for vertical transmission. The increase in cesarean rate in this data may reflect obstetricians attempting to serve their patients in the best way possible given the current climate of constantly evolving guidelines on safest mode of delivery for the mother, infant, and provider. Upholding current recommendations from trusted organizations as new data are published, while also providing individualized support to expecting mothers on most appropriate mode of delivery, will reduce the amount of unnecessary, unplanned cesarean sections and could lessen the psychological impact of delivering during the COVID-19 pandemic.
    Key Points: COVID-19 may result in an increased rate of cesarean delivery for SARS-CoV-2 positive pregnant women. COVID-19 is a commonly reported indication for cesarean section, despite management guidelines urging against this. Although eight neonates tested positive for SARS-CoV-2, all additional fluid and tissue samples tested negative.
    Keywords COVID-19 ; pregnancy ; cesarean delivery ; vaginal delivery ; neonatal outcome ; vertical transmission ; maternal mental health
    Language English
    Publishing date 2020-12-07
    Publisher Thieme Medical Publishers, Inc.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 605671-4
    ISSN 1098-8785 ; 0735-1631
    ISSN (online) 1098-8785
    ISSN 0735-1631
    DOI 10.1055/s-0040-1721658
    Database Thieme publisher's database

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