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  1. Article: COVID-19 Crisis Creates Opportunity towards Global Monitoring & Surveillance.

    Donia, Ahmed / Hassan, Sammer-Ul / Zhang, Xunli / Al-Madboly, Lamiaa / Bokhari, Habib

    Pathogens (Basel, Switzerland)

    2021  Volume 10, Issue 3

    Abstract: ... COVID-19 crisis, how it can be managed, and what measures are required to deal with a current global ... such as that used to combat polio may help in addressing this challenge. The COVID-19 era differs from any previous ... countries (HICs ~20% of the global population) and low-and middle-income countries (LMICs ~ 80 ...

    Abstract The spectrum of emerging new diseases as well as re-emerging old diseases is broadening as infectious agents evolve, adapt, and spread at enormous speeds in response to changing ecosystems. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a recent phenomenon and may take a while to understand its transmission routes from less traveled territories, ranging from fomite exposure routes to wastewater transmission. The critical challenge is how to negotiate with such catastrophic pandemics in high-income countries (HICs ~20% of the global population) and low-and middle-income countries (LMICs ~ 80% of the global population) with a total global population size of approximately eight billion, where practical mass testing and tracing is only a remote possibility, particularly in low-and middle-income countries (LMICs). Keeping in mind the population distribution disparities of high-income countries (HICs) and LMICs and urbanisation trends over recent years, traditional wastewater-based surveillance such as that used to combat polio may help in addressing this challenge. The COVID-19 era differs from any previous pandemics or global health challenges in the sense that there is a great deal of curiosity within the global community to find out everything about this virus, ranging from diagnostics, potential vaccines/therapeutics, and possible routes of transmission. In this regard, the fact that the gut is the common niche for both poliovirus and SARS-CoV-2, and due to the shedding of the virus through faecal material into sewerage systems, the need for long-term wastewater surveillance and developing early warning systems for better preparedness at local and global levels is increasingly apparent. This paper aims to provide an insight into the ongoing COVID-19 crisis, how it can be managed, and what measures are required to deal with a current global international public health concern. Additionally, it shed light on the importance of using wastewater surveillance strategy as an early warning practical tool suitable for massive passive screening, as well as the urgent need for microfluidic technology as a rapid and cost-effective approach tracking SARS-CoV-2 in wastewater.
    Language English
    Publishing date 2021-02-24
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens10030256
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: COVID-19 Crisis Creates Opportunity towards Global Monitoring & Surveillance

    Donia, Ahmed / Hassan, Sammer-ul / Zhang, Xunli / Al-Madboly, Lamiaa / Bokhari, Habib

    Pathogens. 2021 Feb. 24, v. 10, no. 3

    2021  

    Abstract: ... COVID-19 crisis, how it can be managed, and what measures are required to deal with a current global ... such as that used to combat polio may help in addressing this challenge. The COVID-19 era differs from any previous ... countries (HICs ~20% of the global population) and low-and middle-income countries (LMICs ~ 80 ...

    Abstract The spectrum of emerging new diseases as well as re-emerging old diseases is broadening as infectious agents evolve, adapt, and spread at enormous speeds in response to changing ecosystems. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a recent phenomenon and may take a while to understand its transmission routes from less traveled territories, ranging from fomite exposure routes to wastewater transmission. The critical challenge is how to negotiate with such catastrophic pandemics in high-income countries (HICs ~20% of the global population) and low-and middle-income countries (LMICs ~ 80% of the global population) with a total global population size of approximately eight billion, where practical mass testing and tracing is only a remote possibility, particularly in low-and middle-income countries (LMICs). Keeping in mind the population distribution disparities of high-income countries (HICs) and LMICs and urbanisation trends over recent years, traditional wastewater-based surveillance such as that used to combat polio may help in addressing this challenge. The COVID-19 era differs from any previous pandemics or global health challenges in the sense that there is a great deal of curiosity within the global community to find out everything about this virus, ranging from diagnostics, potential vaccines/therapeutics, and possible routes of transmission. In this regard, the fact that the gut is the common niche for both poliovirus and SARS-CoV-2, and due to the shedding of the virus through faecal material into sewerage systems, the need for long-term wastewater surveillance and developing early warning systems for better preparedness at local and global levels is increasingly apparent. This paper aims to provide an insight into the ongoing COVID-19 crisis, how it can be managed, and what measures are required to deal with a current global international public health concern. Additionally, it shed light on the importance of using wastewater surveillance strategy as an early warning practical tool suitable for massive passive screening, as well as the urgent need for microfluidic technology as a rapid and cost-effective approach tracking SARS-CoV-2 in wastewater.
    Keywords COVID-19 infection ; Severe acute respiratory syndrome coronavirus 2 ; cost effectiveness ; diagnostic techniques ; digestive system ; feces ; fomites ; microfluidic technology ; monitoring ; population distribution ; population size ; public health ; therapeutics ; urbanization ; viruses ; wastewater
    Language English
    Dates of publication 2021-0224
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article
    Note NAL-light
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens10030256
    Database NAL-Catalogue (AGRICOLA)

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  3. Article ; Online: COVID-19 Crisis Creates Opportunity towards Global Monitoring & Surveillance

    Ahmed Donia / Sammer-ul Hassan / Xunli Zhang / Lamiaa Al-Madboly / Habib Bokhari

    Pathogens, Vol 10, Iss 3, p

    2021  Volume 256

    Abstract: ... COVID-19 crisis, how it can be managed, and what measures are required to deal with a current global ... such as that used to combat polio may help in addressing this challenge. The COVID-19 era differs from any previous ... countries (HICs ~20% of the global population) and low-and middle-income countries (LMICs ~ 80 ...

    Abstract The spectrum of emerging new diseases as well as re-emerging old diseases is broadening as infectious agents evolve, adapt, and spread at enormous speeds in response to changing ecosystems. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a recent phenomenon and may take a while to understand its transmission routes from less traveled territories, ranging from fomite exposure routes to wastewater transmission. The critical challenge is how to negotiate with such catastrophic pandemics in high-income countries (HICs ~20% of the global population) and low-and middle-income countries (LMICs ~ 80% of the global population) with a total global population size of approximately eight billion, where practical mass testing and tracing is only a remote possibility, particularly in low-and middle-income countries (LMICs). Keeping in mind the population distribution disparities of high-income countries (HICs) and LMICs and urbanisation trends over recent years, traditional wastewater-based surveillance such as that used to combat polio may help in addressing this challenge. The COVID-19 era differs from any previous pandemics or global health challenges in the sense that there is a great deal of curiosity within the global community to find out everything about this virus, ranging from diagnostics, potential vaccines/therapeutics, and possible routes of transmission. In this regard, the fact that the gut is the common niche for both poliovirus and SARS-CoV-2, and due to the shedding of the virus through faecal material into sewerage systems, the need for long-term wastewater surveillance and developing early warning systems for better preparedness at local and global levels is increasingly apparent. This paper aims to provide an insight into the ongoing COVID-19 crisis, how it can be managed, and what measures are required to deal with a current global international public health concern. Additionally, it shed light on the importance of using wastewater surveillance strategy as an early warning practical tool ...
    Keywords SARS-CoV-2 ; waterborne pathogens ; wastewater surveillance ; microbial forensics ; next generation monitoring tools ; lab-on-a-chip ; Medicine ; R
    Subject code 306
    Language English
    Publishing date 2021-02-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: COVID-19 pandemic: the role of community-based pharmacy practice in health equity.

    Roman, Youssef M

    International journal of clinical pharmacy

    2022  Volume 44, Issue 5, Page(s) 1211–1215

    Abstract: ... Compounding this global health crisis, the pandemic did not weigh equally on all community members, but rather ... The COVID-19 pandemic disrupted the landscape of primary care practice, creating new gaps ... to COVID-19 infection, it is critical to dedicate the time to reflect on how we arrived at this point ...

    Abstract The COVID-19 pandemic disrupted the landscape of primary care practice, creating new gaps in chronic disease management and worsening existing health disparities. Community-based pharmacy practices have played a critical role in responding to the pandemic; however, their role in promoting health equity and addressing existing health disparities has not been fully characterized. The objective of this commentary is to highlight some of the challenges and opportunities to cultivate an equitable plain field for communities to overcome significant health crises. Moreover, this commentary underscores the potential role of integrating community-based pharmacies into the public health infrastructure. It is uncommon to find an individual or an organization that has not been impacted by the pandemic. As painful as it has been to lose so many lives due to COVID-19 infection, it is critical to dedicate the time to reflect on how we arrived at this point. Compounding this global health crisis, the pandemic did not weigh equally on all community members, but rather some population groups carried the brunt of the pandemic more than others. The disproportionate burden of COVID-19 has uncovered significant gaps in our healthcare system and the global public health response. Understanding how we arrived at that point in the pandemic is a crucial first step toward achieving health equity. While many factors have led us onto the pandemic path, using national and global health frameworks to address health disparities and monitor health inequalities are worth discussing to delineate a roadmap to optimal population health. As these pandemic lessons challenge the status quo throughout communities, facing these new realities allows us to envision a roadmap for social justice, health equity, and innovative models to optimize health. Leveraging community-based pharmacy services could promote health equity, close growing health gaps, increase access to health care, and rapidly detect and respond to public health threats.
    MeSH term(s) Humans ; COVID-19/epidemiology ; Pandemics ; Health Equity ; Pharmacies ; Health Promotion ; Community Pharmacy Services ; Pharmacy
    Language English
    Publishing date 2022-06-28
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2601204-2
    ISSN 2210-7711 ; 2210-7703 ; 0928-1231
    ISSN (online) 2210-7711
    ISSN 2210-7703 ; 0928-1231
    DOI 10.1007/s11096-022-01440-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Computational pharmacology: New avenues for COVID-19 therapeutics search and better preparedness for future pandemic crises.

    Kanapeckaitė, Austė / Mažeikienė, Asta / Geris, Liesbet / Burokienė, Neringa / Cottrell, Graeme S / Widera, Darius

    Biophysical chemistry

    2022  Volume 290, Page(s) 106891

    Abstract: The COVID-19 pandemic created an unprecedented global healthcare emergency prompting ... understand the complex landscape of COVID-19 drugs. Machine and deep learning allowed us to showcase ... limitations in current chemical libraries for COVID-19 suggesting that both in silico and experimental ...

    Abstract The COVID-19 pandemic created an unprecedented global healthcare emergency prompting the exploration of new therapeutic avenues, including drug repurposing. A large number of ongoing studies revealed pervasive issues in clinical research, such as the lack of accessible and organised data. Moreover, current shortcomings in clinical studies highlighted the need for a multi-faceted approach to tackle this health crisis. Thus, we set out to explore and develop new strategies for drug repositioning by employing computational pharmacology, data mining, systems biology, and computational chemistry to advance shared efforts in identifying key targets, affected networks, and potential pharmaceutical intervention options. Our study revealed that formulating pharmacological strategies should rely on both therapeutic targets and their networks. We showed how data mining can reveal regulatory patterns, capture novel targets, alert about side-effects, and help identify new therapeutic avenues. We also highlighted the importance of the miRNA regulatory layer and how this information could be used to monitor disease progression or devise treatment strategies. Importantly, our work bridged the interactome with the chemical compound space to better understand the complex landscape of COVID-19 drugs. Machine and deep learning allowed us to showcase limitations in current chemical libraries for COVID-19 suggesting that both in silico and experimental analyses should be combined to retrieve therapeutically valuable compounds. Based on the gathered data, we strongly advocate for taking this opportunity to establish robust practices for treating today's and future infectious diseases by preparing solid analytical frameworks.
    MeSH term(s) COVID-19/drug therapy ; Humans ; MicroRNAs ; Pandemics ; Pharmaceutical Preparations ; Small Molecule Libraries
    Chemical Substances MicroRNAs ; Pharmaceutical Preparations ; Small Molecule Libraries
    Language English
    Publishing date 2022-09-11
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 185052-0
    ISSN 1873-4200 ; 0301-4622
    ISSN (online) 1873-4200
    ISSN 0301-4622
    DOI 10.1016/j.bpc.2022.106891
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Effects of the Coronavirus (COVID-19) Pandemic on Social Behaviours

    Gabriel, H. T. Ling / Christina Mee Chyong Ho

    Technium Social Sciences Journal, Vol 7, Pp 312-

    From a Social Dilemma Perspective

    2020  Volume 320

    Abstract: The health crisis of the COVID-19 outbreak has global impacts on humanity and the economy ... microeconomics concepts to analyse and explain the effects of COVID-19 on social behavioural reactions ... which then contribute to curbing the COVID-19 pandemic more effectively. ...

    Abstract The health crisis of the COVID-19 outbreak has global impacts on humanity and the economy. Such pandemic effects are believed to have influenced human behaviour; issues of panic buying (overbuying) and noncompliance among individuals are shown evident. However, the underlying understanding on such behaviours due to the pandemic remains unclear. Therefore, this perspective paper adopts the social dilemma theory and microeconomics concepts to analyse and explain the effects of COVID-19 on social behavioural reactions. It attempts to address the questions of what and why are the behaviours of individuals shown during the coronavirus pandemic and showcase how the theory is associated with current social phenomena. Real scenarios based on media reporting from the sociodemographic context of Malaysia, concerning the following issues; (i) competition over daily essentials; (ii) self-honesty of individuals; and (iii) adherence to government policies and measures enforcement (governance) were discussed. A conceptual framework was developed to illustrate interrelationships between social dilemma concepts and the phenomena. In essence, due to fear, uncertainty and greed, selfinterest and opportunistic (defective/unethical) behaviours of most individuals prevailing over societal collective interest amid the pandemic have been prevalently observed in the above instances, although a cooperative choice can eventually result in a better outcome for everyone. Not only do these non-cooperative behaviours of individuals create inconveniences, dissatisfactions and other forms of negative externalities, they also incentivise others to act selfishly, if no restrictions are imposed, that may eventually cause government interventions failures. This paper demonstrates the relevancy of the social dilemmas theory in better understanding fundamental human behavioural reactions amid the health crisis and the importance of incorporating the findings into government policymaking. These sociopsychological considerations help the government formulate holistic measures, namely stringent sanctions and monitoring enforcement, as well as incentivising cooperative and compliant behaviours of the public, which then contribute to curbing the COVID-19 pandemic more effectively.
    Keywords effects of covid-19 ; malaysia ; pandemic ; self-interest and opportunism ; social behaviour ; social dilemma ; Social sciences (General) ; H1-99 ; covid19
    Subject code 300
    Language English
    Publishing date 2020-04-01T00:00:00Z
    Publisher Technium Science
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Essential Case Management Practices Amidst the Novel Coronavirus Disease 2019 (COVID-19) Crisis: Part 1: Tele-Case Management, Surge Capacity, Discharge Planning, and Transitions of Care.

    Tahan, Hussein M

    Professional case management

    2020  Volume 25, Issue 5, Page(s) 248–266

    Abstract: ... especially acute care.: Findings conclusions: The COVID-19 global pandemic crisis has brought ... of interprofessional health care teams. Their roles are even more necessary during a global pandemic such as COVID-19 ... the potential professional case managers have in support of managing during a crisis such as this global ...

    Abstract Objectives: This is the first of a 2-part article that discusses essential case management practices and strategies amidst the novel coronavirus disease 2019 (COVID-19). The series showcases the potential professional case managers have in support of managing during a crisis such as this global pandemic. Part I discusses reenvisioned roles and responsibilities of case managers and leaders known to address patients' needs during a crisis, with a special focus on telehealth, tele-case management, surge capacity, redeployment, discharge planning, and transitions of care.
    Primary practice settings: Applicable to the various case management practice settings across the continuum of health and human services, especially acute care.
    Findings conclusions: The COVID-19 global pandemic crisis has brought an unprecedented challenge to professional case managers and health care professionals. It also has provided opportunities for innovation and partnerships within and across health care organizations and the various care settings where patients/support systems access necessary services. Most importantly, it created a renewed interest in telehealth and facilitated a wider adoption of such approach to care delivery than ever before. This pandemic has also increased the use of nontraditional sites of care, most importantly those that operate virtually on electronic networks and health information system technologies such as remote visits, e-visits, virtual care, and tele-monitoring. Undoubtedly, these have provided new opportunities for tele-case management services and roles for professional case managers in the virtual world of health and human service delivery.
    Implications for case management practice: Professional case managers are integral members of interprofessional health care teams. Their roles are even more necessary during a global pandemic such as COVID-19. The practice of case management will forever change-for the better. The experience of this crisis in health care has brought about ever-lasting implications for case management professionals. It has raised awareness to sites of care never were as popular before, resulting in an increased need and recognition for tele-case management practice and virtual case managers. It has also forced partnerships and collaborations among the diverse contexts of health care organizations (public, private, or both) and other industries, regardless of whether directly involved in the delivery of care or having a support service role. These new and innovative approaches in the provision of care and case management services will without a doubt become routine expectations beyond the current pandemic period. Of special note are the enhanced roles of case managers in discharge planning and transitions of care.
    MeSH term(s) Betacoronavirus/isolation & purification ; COVID-19 ; Case Management ; Continuity of Patient Care ; Coronavirus Infections/therapy ; Coronavirus Infections/virology ; Humans ; Pandemics ; Patient Discharge ; Pneumonia, Viral/therapy ; Pneumonia, Viral/virology ; SARS-CoV-2 ; Surge Capacity ; Telemedicine
    Keywords covid19
    Language English
    Publishing date 2020-06-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2277201-7
    ISSN 1932-8095 ; 1539-0675 ; 1932-8087 ; 1529-7764
    ISSN (online) 1932-8095 ; 1539-0675
    ISSN 1932-8087 ; 1529-7764
    DOI 10.1097/NCM.0000000000000454
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Essential Case Management Practices Amidst the Novel Coronavirus Disease 2019 (COVID-19) Crisis: Part 1: Tele-Case Management, Surge Capacity, Discharge Planning, and Transitions of Care

    Tahan, Hussein M

    Prof. case manag

    Abstract: ... acute care. FINDINGS CONCLUSIONS: The COVID-19 global pandemic crisis has brought an unprecedented ... of interprofessional health care teams. Their roles are even more necessary during a global pandemic such as COVID-19 ... the potential professional case managers have in support of managing during a crisis such as this global ...

    Abstract OBJECTIVES: This is the first of a 2-part article that discusses essential case management practices and strategies amidst the novel coronavirus disease 2019 (COVID-19). The series showcases the potential professional case managers have in support of managing during a crisis such as this global pandemic. Part I discusses reenvisioned roles and responsibilities of case managers and leaders known to address patients' needs during a crisis, with a special focus on telehealth, tele-case management, surge capacity, redeployment, discharge planning, and transitions of care. PRIMARY PRACTICE SETTINGS: Applicable to the various case management practice settings across the continuum of health and human services, especially acute care. FINDINGS CONCLUSIONS: The COVID-19 global pandemic crisis has brought an unprecedented challenge to professional case managers and health care professionals. It also has provided opportunities for innovation and partnerships within and across health care organizations and the various care settings where patients/support systems access necessary services. Most importantly, it created a renewed interest in telehealth and facilitated a wider adoption of such approach to care delivery than ever before. This pandemic has also increased the use of nontraditional sites of care, most importantly those that operate virtually on electronic networks and health information system technologies such as remote visits, e-visits, virtual care, and tele-monitoring. Undoubtedly, these have provided new opportunities for tele-case management services and roles for professional case managers in the virtual world of health and human service delivery. IMPLICATIONS FOR CASE MANAGEMENT PRACTICE: Professional case managers are integral members of interprofessional health care teams. Their roles are even more necessary during a global pandemic such as COVID-19. The practice of case management will forever change-for the better. The experience of this crisis in health care has brought about ever-lasting implications for case management professionals. It has raised awareness to sites of care never were as popular before, resulting in an increased need and recognition for tele-case management practice and virtual case managers. It has also forced partnerships and collaborations among the diverse contexts of health care organizations (public, private, or both) and other industries, regardless of whether directly involved in the delivery of care or having a support service role. These new and innovative approaches in the provision of care and case management services will without a doubt become routine expectations beyond the current pandemic period. Of special note are the enhanced roles of case managers in discharge planning and transitions of care.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #32452941
    Database COVID19

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