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Article: Transient immune hepatitis as post-coronavirus disease complication: A case report.

Drăgănescu, Anca Cristina / Săndulescu, Oana / Bilașco, Anuța / Kouris, Camelia / Streinu-Cercel, Anca / Luminos, Monica / Streinu-Cercel, Adrian

World journal of clinical cases

2021  Volume 9, Issue 16, Page(s) 4032–4039

Abstract: Background: We report a case of post-coronavirus disease (COVID) immune hepatitis occurring ... 2). The case was interpreted as post-COVID immune hepatitis, with extensive laboratory ... to young patients with mild forms of disease, and a high index of suspicion should be maintained for post ...

Abstract Background: We report a case of post-coronavirus disease (COVID) immune hepatitis occurring in a young male with no pre-existing comorbidities.
Case summary: A previously healthy 21-year-old male patient was admitted to our hospital with mild COVID-19. During the course of in-hospital isolation and monitoring, he developed an alanine aminotransferase (ALT) and aspartate aminotransferase (AST) increase, with the enzymes peaking at day 24 (ALT 15 times the upper normal limit), with preserved liver function. The liver enzyme increase occurred 20 d after the complete clinical remission of COVID-19, and ALT dynamics paralleled the increase in total antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The case was interpreted as post-COVID immune hepatitis, with extensive laboratory investigations excluding other potential causes. The hepatocytolysis remitted 20 d after the peak ALT, without further intervention, with complete recovery, but the total anti-SARS-CoV-2 antibodies continued to increase the next 5 mo following the acute infection.
Conclusion: Close attention should also be paid to young patients with mild forms of disease, and a high index of suspicion should be maintained for post-COVID complications.
Language English
Publishing date 2021-06-01
Publishing country United States
Document type Case Reports
ISSN 2307-8960
ISSN 2307-8960
DOI 10.12998/wjcc.v9.i16.4032
Database MEDical Literature Analysis and Retrieval System OnLINE

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