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Article ; Online: Structure of the mammalian TRPM7, a magnesium channel required during embryonic development.

Duan, Jingjing / Li, Zongli / Li, Jian / Hulse, Raymond E / Santa-Cruz, Ana / Valinsky, William C / Abiria, Sunday A / Krapivinsky, Grigory / Zhang, Jin / Clapham, David E

Proceedings of the National Academy of Sciences of the United States of America

2018  Volume 115, Issue 35, Page(s) E8201–E8210

Abstract: ... expressed protein that is required for mouse embryonic development. TRPM7 contains both an ion channel and ... The transient receptor potential ion channel subfamily M, member 7 (TRPM7), is a ubiquitously ... an α-kinase. The channel domain comprises a nonselective cation channel with notable permeability to Mg ...

Abstract The transient receptor potential ion channel subfamily M, member 7 (TRPM7), is a ubiquitously expressed protein that is required for mouse embryonic development. TRPM7 contains both an ion channel and an α-kinase. The channel domain comprises a nonselective cation channel with notable permeability to Mg
MeSH term(s) Animals ; Embryo, Mammalian ; Embryonic Development ; Evolution, Molecular ; Mice ; Protein Domains ; TRPM Cation Channels/chemistry ; TRPM Cation Channels/metabolism
Chemical Substances TRPM Cation Channels ; Trpm7 protein, mouse (EC 2.7.1.-)
Language English
Publishing date 2018-08-14
Publishing country United States
Document type Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID 209104-5
ISSN 1091-6490 ; 0027-8424
ISSN (online) 1091-6490
ISSN 0027-8424
DOI 10.1073/pnas.1810719115
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