Article: PAX genes in development and disease: the role of PAX2 in urogenital tract development.
The International journal of developmental biology
2002 Volume 46, Issue 4, Page(s) 535–544
Abstract: ... in several PAX genes cause human disease. Here we review the role of PAX2 in kidney development, focusing ... PAX genes play an important role in fetal development. Moreover, heterozygous mutations ... on the morphological effects of PAX2 mutations. We discuss the role of PAX2 in the context of an inhibitory field model ...
| Abstract | PAX genes play an important role in fetal development. Moreover, heterozygous mutations in several PAX genes cause human disease. Here we review the role of PAX2 in kidney development, focusing on the morphological effects of PAX2 mutations. We discuss the role of PAX2 in the context of an inhibitory field model of kidney branching morphogenesis and summarize recent progress in this area. |
|||||
|---|---|---|---|---|---|---|
| MeSH term(s) | Animals ; Apoptosis ; Coloboma/complications ; DNA-Binding Proteins/biosynthesis ; DNA-Binding Proteins/physiology ; Female ; Gene Expression Regulation, Developmental ; Heterozygote ; Homozygote ; Humans ; Immunohistochemistry ; Kidney/abnormalities ; Kidney/embryology ; Kidney/metabolism ; Male ; Mice ; Microscopy, Fluorescence ; Models, Biological ; Models, Genetic ; Mutation ; Oligonucleotide Array Sequence Analysis ; Oviducts/metabolism ; PAX2 Transcription Factor ; Syndrome ; Transcription Factors/biosynthesis ; Transcription Factors/physiology ; Urogenital System/embryology | |||||
| Chemical Substances | DNA-Binding Proteins ; PAX2 Transcription Factor ; PAX2 protein, human ; Pax2 protein, mouse ; Transcription Factors | |||||
| Language | English | |||||
| Publishing date | 2002 | |||||
| Publishing country | Spain | |||||
| Document type | Journal Article ; Research Support, Non-U.S. Gov't ; Review | |||||
| ZDB-ID | 1036070-0 | |||||
| ISSN | 1696-3547 ; 0214-6282 | |||||
| ISSN (online) | 1696-3547 | |||||
| ISSN | 0214-6282 | |||||
| Shelf mark |
|
|||||
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
More links
Kategorien
In stock of ZB MED Cologne/Königswinter
| Zs.A 3202: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG) |
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.