Article ; Online: Comparative study of antifibrotic activity of some magnesium-containing supplements on experimental liver toxicity. Molecular study.
2016 Volume 40, Issue 1, Page(s) 47–56
Abstract: ... compare the therapeutic efficacy of different magnesium (Mg)-containing supplements (formulations A, B ... including collagen that occurs in most types of chronic liver diseases. This study aimed to investigate and ... by intraperitoneal injection of rats with CCl: Results: CCl: Conclusion: Mg supplements were effective in the treatment ...
| Abstract | Introduction: Liver fibrosis is the excessive accumulation of extracellular matrix (ECM) proteins including collagen that occurs in most types of chronic liver diseases. This study aimed to investigate and compare the therapeutic efficacy of different magnesium (Mg)-containing supplements (formulations A, B, and C) on carbon tetrachloride (CCl Methods: Liver fibrosis was induced by intraperitoneal injection of rats with CCl Results: CCl Conclusion: Mg supplements were effective in the treatment of hepatic CCl |
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| MeSH term(s) | Animals ; Antioxidants/metabolism ; Biomarkers/blood ; Carbon Tetrachloride/toxicity ; Dietary Supplements ; Female ; Liver/drug effects ; Liver/metabolism ; Liver/pathology ; Liver Cirrhosis, Experimental/metabolism ; Liver Cirrhosis, Experimental/pathology ; Liver Cirrhosis, Experimental/prevention & control ; Liver Function Tests ; Magnesium/administration & dosage ; Magnesium/chemistry ; Magnesium/therapeutic use ; NF-kappa B/genetics ; Nitric Oxide/biosynthesis ; Organ Size/drug effects ; Rats, Wistar ; Transforming Growth Factor beta1/genetics | |||||
| Chemical Substances | Antioxidants ; Biomarkers ; NF-kappa B ; Transforming Growth Factor beta1 ; Nitric Oxide (31C4KY9ESH) ; Carbon Tetrachloride (CL2T97X0V0) ; Magnesium (I38ZP9992A) | |||||
| Language | English | |||||
| Publishing date | 2016-05-05 | |||||
| Publishing country | United States | |||||
| Document type | Comparative Study ; Journal Article | |||||
| ZDB-ID | 548368-2 | |||||
| ISSN | 1525-6014 ; 0148-0545 | |||||
| ISSN (online) | 1525-6014 | |||||
| ISSN | 0148-0545 | |||||
| DOI | 10.3109/01480545.2016.1172083 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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