Article ; Online: Periodontal pocket and COVID-19: Could there be a possible link?
2020 Volume 146, Page(s) 110355
Abstract: ... presents with pathology very much similar to COVID-19 and a possibility of dual role can be thought ... COVID-19 is the emerging health emergency ruining the well being of individuals and devastating ... the equilibrium of the host is disrupted leading to manifestation of the disease. The Periodontal pocket also ...
| Abstract | COVID-19 is the emerging health emergency ruining the well being of individuals and devastating the global economies. Sustained research focusing on the virus has been on throughout the world. However, no definitive remedies have yet been derived in the containment of the virus. Steady knowledge on the pathogenesis of the virus has revealed certain consistent features specific to the disease which includes massive destruction of the lung due to the presence of excessive angiotensin-converting enzyme receptors (ACE2) which are essential for the viral entry inside the host. Once, access is gained multiplication occurs resulting in suppressing the immune response of the body against the virus. Henceforth, the equilibrium of the host is disrupted leading to manifestation of the disease. The Periodontal pocket also presents with pathology very much similar to COVID-19 and a possibility of dual role can be thought of pertaining to aspects of Periodontal Medicine. |
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| MeSH term(s) | Angiotensin-Converting Enzyme 2/immunology ; COVID-19/etiology ; COVID-19/immunology ; COVID-19/virology ; Cytokines/metabolism ; Dental Models ; Host Microbial Interactions/immunology ; Humans ; Models, Immunological ; Periodontal Pocket/complications ; Periodontal Pocket/immunology ; Periodontal Pocket/virology ; Receptors, Virus/immunology ; Risk Factors ; SARS-CoV-2/pathogenicity |
| Chemical Substances | Cytokines ; Receptors, Virus ; ACE2 protein, human (EC 3.4.17.23) ; Angiotensin-Converting Enzyme 2 (EC 3.4.17.23) |
| Keywords | covid19 |
| Language | English |
| Publishing date | 2020-11-01 |
| Publishing country | United States |
| Document type | Letter |
| ZDB-ID | 193145-3 |
| ISSN | 1532-2777 ; 0306-9877 |
| ISSN (online) | 1532-2777 |
| ISSN | 0306-9877 |
| DOI | 10.1016/j.mehy.2020.110355 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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