Article ; Online: Patients with COVID-19 and neurological manifestations show undetectable SARS-CoV-2 RNA levels in the cerebrospinal fluid.
2020 Volume 96, Page(s) 567–569
Abstract: ... or extremely low levels of SARS-CoV-2 RNA in the cerebrospinal fluid, indicating that viral clearance ... We report that patients with COVID-19 displaying distinct neurological disorders have undetectable ... sensitive molecular tests and the investigation of other neurotropic pathogens to exclude concurrent ...
| Abstract | We report that patients with COVID-19 displaying distinct neurological disorders have undetectable or extremely low levels of SARS-CoV-2 RNA in the cerebrospinal fluid, indicating that viral clearance precede the neurological involvement. This finding points to the need for the development of more sensitive molecular tests and the investigation of other neurotropic pathogens to exclude concurrent neuroinfection. |
|---|---|
| MeSH term(s) | Betacoronavirus ; COVID-19 ; Coronavirus Infections/cerebrospinal fluid ; Coronavirus Infections/diagnosis ; Coronavirus Infections/physiopathology ; Humans ; Nervous System Diseases/virology ; Pandemics ; Pneumonia, Viral/cerebrospinal fluid ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/physiopathology ; RNA, Viral/cerebrospinal fluid ; SARS-CoV-2 |
| Chemical Substances | RNA, Viral |
| Keywords | covid19 |
| Language | English |
| Publishing date | 2020-06-04 |
| Publishing country | Canada |
| Document type | Journal Article |
| ZDB-ID | 1331197-9 |
| ISSN | 1878-3511 ; 1201-9712 |
| ISSN (online) | 1878-3511 |
| ISSN | 1201-9712 |
| DOI | 10.1016/j.ijid.2020.05.123 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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