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  1. TI=Release phenomena and toxicity in polymer based dental restorative materials
  2. AU=Kim Do Kyun David

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  1. Artikel: Release phenomena and toxicity in polymer-based dental restorative materials.

    Fano, Vincenzo / Shatel, Mohamed / Tanzi, Maria Luisa

    Acta bio-medica : Atenei Parmensis

    2007  Band 78, Heft 3, Seite(n) 190–197

    Abstract: In this work, the origin of the release phenomena occuring in resin-based dental restorative ... materials is demonstrated using confocal fluorescence microscopy and tapping mode atomic force microscopy ... have been measured by gravimetric analysis. The different toxicity effects induced by the component ...

    Abstract In this work, the origin of the release phenomena occuring in resin-based dental restorative materials is demonstrated using confocal fluorescence microscopy and tapping mode atomic force microscopy techniques. The surface structure (microcavities, protruded filler particles, grain boundaries, and cracks) produced by water environment on the surface of composite resins and resin-modified glass-ionomeric cements (RMGICs) are shown. The water absorption and the subsequent weight decrease, induced by leaching process, have been measured by gravimetric analysis. The different toxicity effects induced by the component release are described.
    Mesh-Begriff(e) Biocompatible Materials ; Composite Resins/chemistry ; Composite Resins/toxicity ; Dental Cements/chemistry ; Dental Cements/toxicity ; Dental Materials/chemistry ; Dental Materials/toxicity ; Diffusion ; Humans ; Hydrolysis ; Methacrylates ; Microscopy, Atomic Force ; Microscopy, Confocal ; Polymers ; Resins, Synthetic/chemistry ; Resins, Synthetic/toxicity ; Surface Properties
    Chemische Substanzen Biocompatible Materials ; Composite Resins ; Dental Cements ; Dental Materials ; Methacrylates ; Polymers ; Resins, Synthetic ; hydroxyethyl methacrylate (6E1I4IV47V)
    Sprache Englisch
    Erscheinungsdatum 2007-12
    Erscheinungsland Italy
    Dokumenttyp Comparative Study ; Journal Article ; Review
    ZDB-ID 2114240-3
    ISSN 0392-4203
    ISSN 0392-4203
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: How much do resin-based dental materials release? A meta-analytical approach.

    Van Landuyt, K L / Nawrot, Tim / Geebelen, B / De Munck, J / Snauwaert, J / Yoshihara, K / Scheers, Hans / Godderis, Lode / Hoet, P / Van Meerbeek, B

    Dental materials : official publication of the Academy of Dental Materials

    2011  Band 27, Heft 8, Seite(n) 723–747

    Abstract: Objectives: Resin-based dental materials are not inert in the oral environment, and may release ... of components from resin-based dental materials, and to determine how much (order of magnitude ... to be released in organic than in water-based media. Resin-based dental materials might account ...

    Abstract Objectives: Resin-based dental materials are not inert in the oral environment, and may release components, initially due to incomplete polymerization, and later due to degradation. Since there are concerns regarding potential toxicity, more precise knowledge of the actual quantity of released eluates is necessary. However, due to a great variety in analytical methodology employed in different studies and in the presentation of the results, it is still unclear to which quantities of components a patient may be exposed. The objective of this meta-analytical study was to review the literature on the short- and long-term release of components from resin-based dental materials, and to determine how much (order of magnitude) of those components may leach out in the oral cavity.
    Methods: Out of an initial set of 71 studies, 22 were included. In spite of the large statistical incertitude due to the great variety in methodology and lack of complete information (detection limits were seldom mentioned), a meta-analytical mean for the evaluated eluates was calculated. To relate the amount of potentially released material components with the size of restorations, the mean size of standard composite restorations was estimated using a 3D graphical program.
    Results: While the release of monomers was analyzed in many studies, that of additives, such as initiators, inhibitors and stabilizers, was seldom investigated. Significantly more components were found to be released in organic than in water-based media. Resin-based dental materials might account for the total burden of orally ingested bisphenol A, but they may release even higher amounts of monomers, such as HEMA, TEGDMA, BisGMA and UDMA. Compared to these monomers, similar or even higher amounts of additives may elute, even though composites generally only contain very small amounts of additives. A positive correlation was found between the total quantity of released eluates and the volume of extraction solution.
    Significance: There is a clear need for more accurate and standardized analytical research to determine the long-term release from resin-based materials. Several guidelines for standardization are proposed.
    Mesh-Begriff(e) Benzhydryl Compounds ; Bisphenol A-Glycidyl Methacrylate/chemistry ; Chemical Phenomena ; Composite Resins/chemistry ; Dental Materials/chemistry ; Dental Restoration, Permanent ; Humans ; Methacrylates/chemistry ; Phenols/chemistry ; Polyethylene Glycols/chemistry ; Polymerization ; Polymethacrylic Acids/chemistry ; Polyurethanes/chemistry ; Surface Properties ; Time Factors
    Chemische Substanzen Benzhydryl Compounds ; Composite Resins ; Dental Materials ; Methacrylates ; Phenols ; Polymethacrylic Acids ; Polyurethanes ; urethane dimethacrylate luting resin (125523-74-2) ; triethylene glycol dimethacrylate (14I47YJ5EY) ; Polyethylene Glycols (30IQX730WE) ; Bisphenol A-Glycidyl Methacrylate (454I75YXY0) ; hydroxyethyl methacrylate (6E1I4IV47V) ; bisphenol A (MLT3645I99)
    Sprache Englisch
    Erscheinungsdatum 2011-08
    Erscheinungsland England
    Dokumenttyp Journal Article ; Meta-Analysis ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 605995-8
    ISSN 1879-0097 ; 0109-5641
    ISSN (online) 1879-0097
    ISSN 0109-5641
    DOI 10.1016/j.dental.2011.05.001
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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