Article ; Online: Diaphragm dysfunction in severe COVID-19 as determined by neuromuscular ultrasound.
Annals of clinical and translational neurology
2021 Volume 8, Issue 8, Page(s) 1745–1749
Abstract: Many survivors from severe coronavirus disease 2019 (COVID-19) suffer from persistent dyspnea and ... fatigue long after resolution of the active infection. In a cohort of 21 consecutive severe post-COVID-19 ... light on neuromuscular respiratory dysfunction as a contributor to prolonged functional impairments ...
| Abstract | Many survivors from severe coronavirus disease 2019 (COVID-19) suffer from persistent dyspnea and fatigue long after resolution of the active infection. In a cohort of 21 consecutive severe post-COVID-19 survivors admitted to an inpatient rehabilitation hospital, 16 (76%) of them had at least one sonographic abnormality of diaphragm muscle structure or function. This corresponded to a significant reduction in diaphragm muscle contractility as represented by thickening ratio (muscle thickness at maximal inspiration/end-expiration) for the post-COVID-19 compared to non-COVID-19 cohorts. These findings may shed new light on neuromuscular respiratory dysfunction as a contributor to prolonged functional impairments after hospitalization for post-COVID-19. |
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| MeSH term(s) | Adult ; Aged ; Aged, 80 and over ; COVID-19/complications ; COVID-19/diagnostic imaging ; COVID-19/pathology ; COVID-19/physiopathology ; Diaphragm/diagnostic imaging ; Diaphragm/pathology ; Diaphragm/physiopathology ; Female ; Hospitals, Rehabilitation ; Humans ; Inpatients ; Male ; Middle Aged ; Ultrasonography/methods |
| Language | English |
| Publishing date | 2021-07-11 |
| Publishing country | United States |
| Document type | Journal Article |
| ZDB-ID | 2740696-9 |
| ISSN | 2328-9503 ; 2328-9503 |
| ISSN (online) | 2328-9503 |
| ISSN | 2328-9503 |
| DOI | 10.1002/acn3.51416 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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