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  1. Article ; Online: Pulmonary Embolism Response Team utilization during the COVID-19 pandemic.

    Finn, Matthew T / Gogia, Shawn / Ingrassia, Joseph J / Cohen, Matthew / Madhavan, Mahesh V / Nabavi Nouri, Shayan / Brailovsky, Yevgeniy / Masoumi, Amir / Fried, Justin A / Uriel, Nir / Agerstrand, Cara I / Eisenberger, Andrew / Einstein, Andrew J / Brodie, Daniel / B Rosenzweig, Erika / Leon, Martin B / Takeda, Koji / Pucillo, Anthony / Green, Philip /
    Kirtane, Ajay J / Parikh, Sahil A / Sethi, Sanjum S

    Vascular medicine (London, England)

    2021  Volume 26, Issue 4, Page(s) 426–433

    Abstract: ... Limited data are available on the utilization of the Pulmonary Embolism Response Team (PERT ... bleeding. The frequency of PERT utilization was nearly threefold higher during March and April 2020 ( ... in the setting of the COVID-19 global pandemic. We performed a single-center study to evaluate treatment ...

    Abstract Coronavirus disease 2019 (COVID-19) may predispose patients to venous thromboembolism (VTE). Limited data are available on the utilization of the Pulmonary Embolism Response Team (PERT) in the setting of the COVID-19 global pandemic. We performed a single-center study to evaluate treatment, mortality, and bleeding outcomes in patients who received PERT consultations in March and April 2020, compared to historical controls from the same period in 2019. Clinical data were abstracted from the electronic medical record. The primary study endpoints were inpatient mortality and GUSTO moderate-to-severe bleeding. The frequency of PERT utilization was nearly threefold higher during March and April 2020 (
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; COVID-19/complications ; COVID-19/diagnosis ; COVID-19/mortality ; COVID-19/therapy ; Female ; Health Resources/trends ; Health Services Needs and Demand/trends ; Hemorrhage/etiology ; Hemorrhage/mortality ; Hospital Mortality ; Humans ; Male ; Middle Aged ; Patient Care Team/trends ; Practice Patterns, Physicians'/trends ; Pulmonary Embolism/diagnosis ; Pulmonary Embolism/etiology ; Pulmonary Embolism/mortality ; Pulmonary Embolism/therapy ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Thrombolytic Therapy/trends ; Time Factors ; Treatment Outcome ; Venous Thromboembolism/diagnosis ; Venous Thromboembolism/etiology ; Venous Thromboembolism/mortality ; Venous Thromboembolism/therapy
    Language English
    Publishing date 2021-04-04
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 1311628-9
    ISSN 1477-0377 ; 1358-863X
    ISSN (online) 1477-0377
    ISSN 1358-863X
    DOI 10.1177/1358863X21995896
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Pulmonary Embolism Response Team activation during the COVID-19 pandemic in a New York City Academic Hospital: a retrospective cohort analysis.

    Kwok, Benjamin / Brosnahan, Shari B / Amoroso, Nancy E / Goldenberg, Ronald M / Heyman, Brooke / Horowitz, James M / Jamin, Catherine / Sista, Akhilesh K / Smith, Deane E / Yuriditsky, Eugene / Maldonado, Thomas S

    Journal of thrombosis and thrombolysis

    2020  Volume 51, Issue 2, Page(s) 330–338

    Abstract: ... 7 vs. 13.2 ± 12.7 days, p = 0.02). PERT utilization decreased during the COVID-19 pandemic and ... for patients diagnosed with acute PE changed during the COVID-19 pandemic. This is a retrospective cohort study ... and pulmonary embolism (PE). Pulmonary Embolism Response Teams (PERT) have previously been associated ...

    Abstract Coronavirus disease 2019 (COVID-19) is associated with increased rates of deep vein thrombosis (DVT) and pulmonary embolism (PE). Pulmonary Embolism Response Teams (PERT) have previously been associated with improved outcomes. We aimed to investigate whether PERT utilization, recommendations, and outcomes for patients diagnosed with acute PE changed during the COVID-19 pandemic. This is a retrospective cohort study of all adult patients with acute PE who received care at an academic hospital system in New York City between March 1st and April 30th, 2020. These patients were compared against historic controls between March 1st and April 30th, 2019. PE severity, PERT utilization, initial management, PERT recommendations, and outcomes were compared. There were more cases of PE during the pandemic (82 vs. 59), but less PERT activations (26.8% vs. 64.4%, p < 0.001) despite similar markers of PE severity. PERT recommendations were similar before and during the pandemic; anticoagulation was most recommended (89.5% vs. 86.4%, p = 0.70). During the pandemic, those with PERT activations were more likely to be female (63.6% vs. 31.7%, p = 0.01), have a history of DVT/PE (22.7% vs. 1.7%, p = 0.01), and to be SARS-CoV-2 PCR negative (68.2% vs. 38.3% p = 0.02). PERT activation during the pandemic is associated with decreased length of stay (7.7 ± 7.7 vs. 13.2 ± 12.7 days, p = 0.02). PERT utilization decreased during the COVID-19 pandemic and its activation was associated with different biases. PERT recommendations and outcomes were similar before and during the pandemic, and led to decreased length of stay during the pandemic.
    MeSH term(s) Aged ; Aged, 80 and over ; Anticoagulants/administration & dosage ; COVID-19/blood ; COVID-19/epidemiology ; Female ; Hospitals, University ; Humans ; Male ; Middle Aged ; New York City/epidemiology ; Pandemics ; Practice Guidelines as Topic ; Pulmonary Embolism/blood ; Pulmonary Embolism/drug therapy ; Pulmonary Embolism/epidemiology ; Retrospective Studies ; SARS-CoV-2/metabolism ; Severity of Illness Index ; COVID-19 Drug Treatment
    Chemical Substances Anticoagulants
    Keywords covid19
    Language English
    Publishing date 2020-08-26
    Publishing country Netherlands
    Document type Clinical Trial ; Journal Article
    ZDB-ID 1230645-9
    ISSN 1573-742X ; 0929-5305
    ISSN (online) 1573-742X
    ISSN 0929-5305
    DOI 10.1007/s11239-020-02264-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Pulmonary Embolism Response Team activation during the COVID-19 pandemic in a New York City Academic Hospital: a retrospective cohort analysis

    Kwok, Benjamin / Brosnahan, Shari B / Amoroso, Nancy E / Goldenberg, Ronald M / Heyman, Brooke / Horowitz, James M / Jamin, Catherine / Sista, Akhilesh K / Smith, Deane E / Yuriditsky, Eugene / Maldonado, Thomas S

    J. thromb. thrombolysis

    Abstract: ... 7 vs. 13.2 ± 12.7 days, p = 0.02). PERT utilization decreased during the COVID-19 pandemic and ... for patients diagnosed with acute PE changed during the COVID-19 pandemic. This is a retrospective cohort study ... and pulmonary embolism (PE). Pulmonary Embolism Response Teams (PERT) have previously been associated ...

    Abstract Coronavirus disease 2019 (COVID-19) is associated with increased rates of deep vein thrombosis (DVT) and pulmonary embolism (PE). Pulmonary Embolism Response Teams (PERT) have previously been associated with improved outcomes. We aimed to investigate whether PERT utilization, recommendations, and outcomes for patients diagnosed with acute PE changed during the COVID-19 pandemic. This is a retrospective cohort study of all adult patients with acute PE who received care at an academic hospital system in New York City between March 1st and April 30th, 2020. These patients were compared against historic controls between March 1st and April 30th, 2019. PE severity, PERT utilization, initial management, PERT recommendations, and outcomes were compared. There were more cases of PE during the pandemic (82 vs. 59), but less PERT activations (26.8% vs. 64.4%, p < 0.001) despite similar markers of PE severity. PERT recommendations were similar before and during the pandemic; anticoagulation was most recommended (89.5% vs. 86.4%, p = 0.70). During the pandemic, those with PERT activations were more likely to be female (63.6% vs. 31.7%, p = 0.01), have a history of DVT/PE (22.7% vs. 1.7%, p = 0.01), and to be SARS-CoV-2 PCR negative (68.2% vs. 38.3% p = 0.02). PERT activation during the pandemic is associated with decreased length of stay (7.7 ± 7.7 vs. 13.2 ± 12.7 days, p = 0.02). PERT utilization decreased during the COVID-19 pandemic and its activation was associated with different biases. PERT recommendations and outcomes were similar before and during the pandemic, and led to decreased length of stay during the pandemic.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #754365
    Database COVID19

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