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  1. Article: Disposable microfluidic devices: fabrication, function, and application.

    Fiorini, Gina S / Chiu, Daniel T

    BioTechniques

    2005  Volume 38, Issue 3, Page(s) 429–446

    Abstract: ... microfluidic systems, including replica and injection molding, embossing, and laser ablation. Also described ... on disposable plastic devices. Included is an overview of the common methods used in the fabrication of polymer ... implemented in a microfluidic format. Finally, a few select biotechnological applications of microfluidics are ...

    Abstract This review article describes recent developments in microfluidics, with special emphasis on disposable plastic devices. Included is an overview of the common methods used in the fabrication of polymer microfluidic systems, including replica and injection molding, embossing, and laser ablation. Also described are the different methods by which on-chip operations--such as the pumping and valving of fluid flow, the mixing of different reagents, and the separation and detection of different chemical species--have been implemented in a microfluidic format. Finally, a few select biotechnological applications of microfluidics are presented to illustrate both the utility of this technology and its potential for development in the future.
    MeSH term(s) Biosensing Techniques/instrumentation ; Biosensing Techniques/methods ; Biosensing Techniques/trends ; Chemistry Techniques, Analytical/instrumentation ; Chemistry Techniques, Analytical/methods ; Chemistry Techniques, Analytical/trends ; Disposable Equipment ; Equipment Design ; Equipment Failure Analysis ; Microarray Analysis/instrumentation ; Microarray Analysis/methods ; Microarray Analysis/trends ; Microfluidic Analytical Techniques/instrumentation ; Microfluidic Analytical Techniques/methods ; Microfluidic Analytical Techniques/trends ; Technology Assessment, Biomedical
    Language English
    Publishing date 2005-03
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, U.S. Gov't, P.H.S. ; Review
    ZDB-ID 48453-2
    ISSN 1940-9818 ; 0736-6205
    ISSN (online) 1940-9818
    ISSN 0736-6205
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Disposable paper-based microfluidics for fertility testing

    Misagh Rezapour Sarabi / Defne Yigci / M. Munzer Alseed / Begum Aydogan Mathyk / Baris Ata / Cihan Halicigil / Savas Tasoglu

    iScience, Vol 25, Iss 9, Pp 104986- (2022)

    2022  

    Abstract: ... we review advancements in fabrication methods for paper-based microfluidic devices and their emerging ... sorting remains crucial in advancing reproductive medicine. Microfluidic technologies have emerged ... microfluidic systems. ...

    Abstract Summary: Fifteen percent of couples of reproductive age suffer from infertility globally and the burden of infertility disproportionately impacts residents of developing countries. Assisted reproductive technologies (ARTs), including in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI), have been successful in overcoming various reasons for infertility including borderline and severe male factor infertility which consists of 20%–30% of all infertile cases. Approximately half of male infertility cases stem from suboptimal sperm parameters. Therefore, healthy/normal sperm enrichment and sorting remains crucial in advancing reproductive medicine. Microfluidic technologies have emerged as promising tools to develop in-home rapid fertility tests and point-of-care (POC) diagnostic tools. Here, we review advancements in fabrication methods for paper-based microfluidic devices and their emerging fertility testing applications assessing sperm concentration, sperm motility, sperm DNA analysis, and other sperm functionalities, and provide a glimpse into future directions for paper-based fertility microfluidic systems.
    Keywords Medical device in health technology ; Biotechnology ; Biodevices ; Science ; Q
    Language English
    Publishing date 2022-09-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Disposable microfluidic devices

    Gina S. Fiorini / Daniel T. Chiu

    BioTechniques, Vol 38, Iss 3, Pp 429-

    fabrication, function, and application

    2005  Volume 446

    Abstract: ... microfluidic systems, including replica and injection molding, embossing, and laser ablation. Also described ... on disposable plastic devices. Included is an overview of the common methods used in the fabrication of polymer ... implemented in a microfluidic format. Finally, a few select biotechnological applications of microfluidics are ...

    Abstract This review article describes recent developments in microfluidics, with special emphasis on disposable plastic devices. Included is an overview of the common methods used in the fabrication of polymer microfluidic systems, including replica and injection molding, embossing, and laser ablation. Also described are the different methods by which on-chip operations—such as the pumping and valving of fluid flow, the mixing of different reagents, and the separation and detection of different chemical species—have been implemented in a microfluidic format. Finally, a few select biotechnological applications of microfluidics are presented to illustrate both the utility of this technology and its potential for development in the future.
    Keywords Biology (General) ; QH301-705.5
    Language English
    Publishing date 2005-03-01T00:00:00Z
    Publisher Future Science Ltd
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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