Article ; Online: Neurological manifestations in patients with symptomatic COVID-19 admitted to the Bafoussam Regional Hospital, Cameroon.
The Pan African medical journal
2021 Volume 38, Page(s) 326
Abstract: ... confirmed COVID-19 cases admitted to the Bafoussam Regional Hospital between March and September 2020 ... Conclusion: neurological manifestations are frequent and heterogeneous in patients with symptomatic COVID-19 ... of neurological symptoms. This study aimed to report neurological manifestations associated with symptomatic COVID-19 ...
| Abstract | Introduction: although the main manifestations of COVID-19 are respiratory, several neurological symptoms and complications have also been reported. The pandemic seems to have some epidemiological specificities in sub-Saharan Africa, and this may be reflected in the type and frequency of neurological symptoms. This study aimed to report neurological manifestations associated with symptomatic COVID-19 in a sub-Saharan African setting. Methods: we conducted a retrospective review of symptomatic PCR-confirmed COVID-19 cases admitted to the Bafoussam Regional Hospital between March and September 2020. Patients' files were reviewed at discharge by a consultant neurologist. Socio-demographic characteristics, co-morbidities, symptoms on admission, neurological symptoms during hospitalization, management, and in-hospital outcome were recorded. Comparisons between patients with and without neurological symptoms were performed using Fisher's exact and Mann-Whitney U test. Results: we enrolled 177 symptomatic patients (68% men). Mean age was 54.6 ± 17.8 years (range 2-99 years). Co-morbidities were present in 57.6% of patients, including hypertension (27.1%) and diabetes mellitus (25.4%). Neurological symptoms were found in 113 (63.8%) patients. The most frequent were headache (39.0%), myalgia (35.6%), anosmia (11.9%), impaired consciousness (10.7%) and delirium (5.6%). Regarding the presenting symptoms, fever was more frequent in patients with neurological symptoms than in those without (81.4% versus 50.0%, p< 0.001), while digestive symptoms were less frequent in patients with neurological symptoms (0.9% versus 9.4%, p= 0.004). Conclusion: neurological manifestations are frequent and heterogeneous in patients with symptomatic COVID-19. Further studies are needed to clarify the pathophysiology of neurological symptoms in COVID-19 and their impact on patients' long-term outcome. |
|---|---|
| MeSH term(s) | Adolescent ; Adult ; Aged ; Aged, 80 and over ; COVID-19/complications ; Cameroon ; Child ; Child, Preschool ; Comorbidity ; Female ; Fever/epidemiology ; Fever/virology ; Hospitalization ; Humans ; Male ; Middle Aged ; Nervous System Diseases/epidemiology ; Nervous System Diseases/physiopathology ; Nervous System Diseases/virology ; Retrospective Studies ; Young Adult |
| Language | English |
| Publishing date | 2021-04-05 |
| Publishing country | Uganda |
| Document type | Journal Article |
| ZDB-ID | 2514347-5 |
| ISSN | 1937-8688 ; 1937-8688 |
| ISSN (online) | 1937-8688 |
| ISSN | 1937-8688 |
| DOI | 10.11604/pamj.2021.38.326.28973 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
More links
Kategorien
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.