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  1. Article ; Online: Pulmonary Tuberculosis in a Patient with COVID-19 Pneumonia.

    Fonseca, Cyro Antonio / Zanetti, Gláucia / Marchiori, Edson

    Revista da Sociedade Brasileira de Medicina Tropical

    2021  Volume 54, Page(s) e03142021

    MeSH term(s) COVID-19 ; Humans ; SARS-CoV-2 ; Tuberculosis, Pulmonary/complications
    Language English
    Publishing date 2021-07-02
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 1038126-0
    ISSN 1678-9849 ; 0037-8682
    ISSN (online) 1678-9849
    ISSN 0037-8682
    DOI 10.1590/0037-8682-0314-2021
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  2. Article ; Online: Pulmonary Tuberculosis in a Patient with COVID-19 Pneumonia

    Cyro Antonio Fonseca Jr / Gláucia Zanetti / Edson Marchiori

    Revista da Sociedade Brasileira de Medicina Tropical, Vol

    2021  Volume 54

    Keywords Arctic medicine. Tropical medicine ; RC955-962
    Language English
    Publishing date 2021-07-01T00:00:00Z
    Publisher Sociedade Brasileira de Medicina Tropical (SBMT)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: COVID-19 pneumonia in active pulmonary tuberculosis patients: a series of cases.

    Shi, Ruiqi / Duan, Qiuxia / Dong, Weihao / Guo, Yong / Xu, Shengwei

    Minerva medica

    2021  Volume 114, Issue 4, Page(s) 550–551

    MeSH term(s) Humans ; COVID-19/complications ; Tuberculosis, Pulmonary/complications
    Language English
    Publishing date 2021-11-11
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 123586-2
    ISSN 1827-1669 ; 0026-4806
    ISSN (online) 1827-1669
    ISSN 0026-4806
    DOI 10.23736/S0026-4806.21.07882-4
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  4. Article: COVID-19 Pneumonia with Delayed Viral Clearance in a Patient with Active Drug-resistant Pulmonary Tuberculosis.

    Sarma, Utpal / Mishra, Vipul / Goel, Jyoti / Yadav, Sanjeev / Sharma, Shreya / Sherawat, Rohit K

    Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine

    2020  Volume 24, Issue 11, Page(s) 1132–1134

    Abstract: ... Sharma S, Sherawat RK. COVID-19 Pneumonia with Delayed Viral Clearance in a Patient with Active Drug ... COVID pneumonia patient presents with fever, cough, and breathing difficulty. Many respiratory ... pathogens have such clinical presentations and pulmonary tuberculosis (PTB) is one of them, which is ...

    Abstract COVID pneumonia patient presents with fever, cough, and breathing difficulty. Many respiratory pathogens have such clinical presentations and pulmonary tuberculosis (PTB) is one of them, which is prevalent in the Indian subcontinent. Herein, we are presenting a case of dual infection with severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) and drug-resistant PTB [likely multidrug resistance (MDR)] in a patient with chronic kidney disease (CKD) and type 2 diabetes mellitus, a clinical course further complicated by a prolonged viral clearance.
    How to cite this article: Sarma U, Mishra V, Goel J, Yadav S, Sharma S, Sherawat RK. COVID-19 Pneumonia with Delayed Viral Clearance in a Patient with Active Drug-resistant Pulmonary Tuberculosis. Indian J Crit Care Med 2020;24(11):1132-1134.
    Language English
    Publishing date 2020-11-05
    Publishing country India
    Document type Case Reports
    ZDB-ID 2121263-6
    ISSN 1998-359X ; 0972-5229
    ISSN (online) 1998-359X
    ISSN 0972-5229
    DOI 10.5005/jp-journals-10071-23662
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  5. Article: Infectious Complications of Pulmonary Sarcoidosis.

    Valeyre, Dominique / Bernaudin, Jean-François / Brauner, Michel / Nunes, Hilario / Jeny, Florence

    Journal of clinical medicine

    2024  Volume 13, Issue 2

    Abstract: ... crucial to prevent severe tuberculosis. Severity in COVID-19 appears to be increased by comorbidities ... countries. Additionally, parallel emphasis should be placed on vaccinations, especially against COVID-19. ... patients. Pulmonary destructive lesions of advanced sarcoidosis increase the incidence of chronic ...

    Abstract In this review, the infectious complications observed in sarcoidosis are considered from a practical point of view to help the clinician not to overlook them in a difficult context, as pulmonary sarcoidosis makes the recognition of superinfections more difficult. An increased incidence of community-acquired pneumonia and of opportunistic pneumonia has been reported, especially in immunosuppressed patients. Pulmonary destructive lesions of advanced sarcoidosis increase the incidence of chronic pulmonary aspergillosis and infection by other agents. Screening and treatment of latent tuberculosis infection are crucial to prevent severe tuberculosis. Severity in COVID-19 appears to be increased by comorbidities rather than by sarcoidosis per se. The diagnosis of infectious complications can be challenging and should be considered as a potential differential diagnosis when the exacerbation of sarcoidosis is suspected. These complications not only increase the need for hospitalizations, but also increase the risk of death. This aspect must be carefully considered when assessing the overall health burden associated with sarcoidosis. The impact of immune dysregulation on infectious risk is unclear except in exceptional cases. In the absence of evidence-based studies on immunosuppressants in the specific context of pulmonary sarcoidosis, it is recommended to apply guidelines used in areas outside sarcoidosis. Preventive measures are essential, beginning with an appropriate use of immunosuppressants and the avoidance of unjustified treatments and doses. This approach should take into account the risk of tuberculosis, especially in highly endemic countries. Additionally, parallel emphasis should be placed on vaccinations, especially against COVID-19.
    Language English
    Publishing date 2024-01-07
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13020342
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  6. Article: The effectiveness of glucocorticoid treatment in post-COVID-19 pulmonary involvement.

    Mizera, Jan / Genzor, Samuel / Sova, Milan / Stanke, Ladislav / Burget, Radim / Jakubec, Petr / Vykopal, Martin / Pobeha, Pavol / Zapletalová, Jana

    Pneumonia (Nathan Qld.)

    2024  Volume 16, Issue 1, Page(s) 2

    Abstract: Rationale: Persistent respiratory symptoms following Coronavirus Disease 2019 (COVID-19) are ... was in line with Czech national guidelines.: Results: The study involved 2729 COVID-19 survivors ... patients.: Patients and methods: Post-COVID patients were recruited into a prospective single-center ...

    Abstract Rationale: Persistent respiratory symptoms following Coronavirus Disease 2019 (COVID-19) are associated with residual radiological changes in lung parenchyma, with a risk of development into lung fibrosis, and with impaired pulmonary function. Previous studies hinted at the possible efficacy of corticosteroids (CS) in facilitating the resolution of post-COVID residual changes in the lungs, but the available data is limited.
    Aim: To evaluate the effects of CS treatment in post-COVID respiratory syndrome patients.
    Patients and methods: Post-COVID patients were recruited into a prospective single-center observational study and scheduled for an initial (V1) and follow-up visit (V2) at the Department of Respiratory Medicine and Tuberculosis, University Hospital Olomouc, comprising of pulmonary function testing, chest x-ray, and complex clinical examination. The decision to administer CS or maintain watchful waiting (WW) was in line with Czech national guidelines.
    Results: The study involved 2729 COVID-19 survivors (45.7% male; mean age: 54.6). From 2026 patients with complete V1 data, 131 patients were indicated for CS therapy. These patients showed significantly worse radiological and functional impairment at V1. Mean initial dose was 27.6 mg (SD ± 10,64), and the mean duration of CS therapy was 13.3 weeks (SD ± 10,06). Following therapy, significantly better improvement of static lung volumes and transfer factor for carbon monoxide (DLCO), and significantly better rates of good or complete radiological and subjective improvement were observed in the CS group compared to controls with available follow-up data (n = 894).
    Conclusion: Better improvement of pulmonary function, radiological findings and subjective symptoms were observed in patients CS compared to watchful waiting. Our findings suggest that glucocorticoid therapy could benefit selected patients with persistent dyspnea, significant radiological changes, and decreased DLCO.
    Language English
    Publishing date 2024-02-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2803296-2
    ISSN 2200-6133
    ISSN 2200-6133
    DOI 10.1186/s41479-023-00123-7
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  7. Article ; Online: Ribociclib-induced pulmonary infiltrates in a patient with breast cancer.

    Ünsal, Oktay / Özet, Ahmet

    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

    2023  Volume 29, Issue 6, Page(s) 1537–1540

    Abstract: ... Pneumonitis, interstitial lung disease, tuberculosis, COVID-19 and other viral agents were excluded ... in the patient. A minimal increase in pulmonary infiltrates was observed in the follow-up. However, the patient ... The pulmonary infiltrates that developed in the patient increased with continued use of ribociclib, suggesting ...

    Abstract Introduction: Breast cancer is the most common cancer in women worldwide. One of the treatment choices used in hormone receptor positive and HER2 expression negative metastatic breast cancer is cyclin dependent kinase 4/6 (CDK) inhibitors. There are differences between the effects and adverse events of all CDK4/6 inhibitors. In this report, we describe a 48-year-old female patient with breast cancer who developed pulmonary infiltrates secondary to drug in the second year of follow-up with Ribociclib therapy.
    Case report: The patient who used ribociclib for metastatic breast cancer was admitted to hospital for routine controls. The patient, in the eighth month of ribociclib treatment, had no active complaints. In the patient's imaging, pulmonary infiltrates were detected in the lower lobe of the right lung.
    Management and outcome: The drug was continued in the patient who was asymptomatic and had no infectious signs. Pneumonitis, interstitial lung disease, tuberculosis, COVID-19 and other viral agents were excluded in the patient. A minimal increase in pulmonary infiltrates was observed in the follow-up. However, the patient who does not have any complaints is currently continuing ribociclib at 600 mg/day.
    Discussion: The pulmonary infiltrates that developed in the patient increased with continued use of ribociclib, suggesting that this was due to ribociclib. The Naranjo Adverse Drug Reaction Probability Scale also indicates probable relationship.
    Language English
    Publishing date 2023-07-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 1330764-2
    ISSN 1477-092X ; 1078-1552
    ISSN (online) 1477-092X
    ISSN 1078-1552
    DOI 10.1177/10781552231192005
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    Zs.A 4488: Show issues Location:
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  8. Article: Isolated pulmonary embolism - a specific clinical entity?

    Hirmerová, Jana / Bílková, Simona / Woznica, Vlastimil

    Vnitrni lekarstvi

    2023  Volume 69, Issue 1, Page(s) 8–13

    Abstract: ... with Behçet´s disease, sickle cell anemia, chronic obstructive pulmonary disease, tuberculosis or covid ... pneumonia. Pulmonary artery thrombosis in situ may differ from classical pulmonary embolism in prognosis ... arteries. However, in half of the patients with pulmonary embolism, deep vein thrombosis is not found. One potential ...

    Title translation Izolovaná plicní embolie – specifická klinická jednotka?
    Abstract Pulmonary embolism in classical meaning is a complication of deep vein thrombosis (usually in the leg veins), developing after a part of the thrombus dislodged and got wedged in pulmonary arteries. However, in half of the patients with pulmonary embolism, deep vein thrombosis is not found. One potential explanation is a different, less common location of the thrombus or previous complete embolization of the whole thrombotic mass. Another possibility is pulmonary artery thrombosis in situ, which is a specific clinical entity associated with some typical risk factors. It develops in the place of vascular injury, as a consequence of hypoxia, inflammatory changes, endothelial dysfunction and injury. Pulmonary artery thrombosis in situ can be a complication after lung resection, radiation therapy, chest trauma, in the patients with Behçet´s disease, sickle cell anemia, chronic obstructive pulmonary disease, tuberculosis or covid pneumonia. Pulmonary artery thrombosis in situ may differ from classical pulmonary embolism in prognosis as well as in therapeutic approach.
    MeSH term(s) Humans ; COVID-19 ; Pulmonary Embolism/diagnosis ; Pulmonary Embolism/etiology ; Pulmonary Embolism/therapy ; Venous Thrombosis/drug therapy ; Thrombosis ; Pulmonary Artery
    Language English
    Publishing date 2023-02-20
    Publishing country Czech Republic
    Document type Journal Article
    ZDB-ID 138213-5
    ISSN 1801-7592 ; 0042-773X
    ISSN (online) 1801-7592
    ISSN 0042-773X
    DOI 10.36290/vnl.2023.001
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  9. Article: COVID-19 and Pulmonary Tuberculosis Coinfection in a Moroccan Patient with Pulmonary Embolism: A Case Report and Literature Review.

    Zouaki, Imane / Chahbi, Zakaria / Raiteb, Mohamed / Zyani, Mohamed

    Case reports in infectious diseases

    2022  Volume 2022, Page(s) 1522876

    Abstract: ... diagnosis of an active pulmonary TB infection and a COVID-19 pneumonia. We present a case of a sixty-seven ... year-old male patient who was admitted to our COVID-19 emergency department with a diagnosis of COVID ... Emerging cases of coinfection of coronavirus disease 2019 (COVID-19) and tuberculosis (TB ...

    Abstract Emerging cases of coinfection of coronavirus disease 2019 (COVID-19) and tuberculosis (TB), although rare, have attracted the attention of health systems around the world and have arisen many concerns about the diagnosis, treatment, and prognosis of this coinfection especially in high TB burden countries. Here, we report a rare case and, to the best of our knowledge, the first reported case in Morocco of simultaneous diagnosis of an active pulmonary TB infection and a COVID-19 pneumonia. We present a case of a sixty-seven-year-old male patient who was admitted to our COVID-19 emergency department with a diagnosis of COVID-19 pneumonia, confirmed by nasopharyngeal swab's polymerase chain reaction (PCR) for detection of SARS-CoV-2. The atypical radiological findings suggested a TB coinfection which was later confirmed by sputum cultures and Xpert MTB/Rif assay. The patient also presented some complications including thrombosis of the left leg, pulmonary embolism and inaugural ketosis. Treatment was administered as per local protocols: broad spectrum antibiotics, corticosteroids, fixed dose-combination of antituberculosis treatment along with hydration and insulin therapy for ketosis treatment and anticoagulation. The patient was discharged after twenty-three days of hospitalization. Due to the currently limited data, further studies are necessary to establish any possible correlation between COVID-19 infection and the progression of a latent and/or the severity of an active TB infection.
    Language English
    Publishing date 2022-07-30
    Publishing country Egypt
    Document type Case Reports
    ZDB-ID 2627642-2
    ISSN 2090-6633 ; 2090-6625
    ISSN (online) 2090-6633
    ISSN 2090-6625
    DOI 10.1155/2022/1522876
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  10. Article ; Online: Pulmonary tuberculosis presenting as acute respiratory distress syndrome.

    Chopra, Neha / Halkur Shankar, Sujay / Biswas, Sagnik / Ray, Animesh

    BMJ case reports

    2021  Volume 14, Issue 1

    Abstract: ... presenting with ARDS. They were initially worked up for viral aetiologies in view of the ongoing COVID-19 ... of our patients succumbed to nosocomial pneumonia, while the other was discharged to follow-up. ... Pulmonary tuberculosis (TB) may present in the form of parenchymal disease or extraparenchymal ...

    Abstract Pulmonary tuberculosis (TB) may present in the form of parenchymal disease or extraparenchymal disease. Patients with TB as a primary cause of respiratory failure requiring mechanical ventilation have been reported to have mortality rates ranging between 47% and 80%. However, acute respiratory distress syndrome (ARDS) as a presentation of TB is rarely reported. We describe two cases of immunocompetent women presenting with ARDS. They were initially worked up for viral aetiologies in view of the ongoing COVID-19 pandemic but were later diagnosed to have microbiologically proven parenchymal pulmonary TB. One of our patients succumbed to nosocomial pneumonia, while the other was discharged to follow-up.
    MeSH term(s) Adult ; COVID-19/diagnosis ; Diagnosis, Differential ; Female ; Humans ; Respiratory Distress Syndrome/etiology ; Tuberculosis, Pulmonary/complications ; Tuberculosis, Pulmonary/diagnosis ; Young Adult
    Language English
    Publishing date 2021-01-25
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2020-237664
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