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Article ; Online: Male predominance in disease severity and mortality in a low Covid-19 epidemic and low case-fatality area - a population-based registry study.

Forsblom, Erik / Silén, Suvi / Kortela, Elisa / Ahava, Maarit / Kreivi, Hanna-Riikka / Holmberg, Ville / Järvinen, Asko / Hästbacka, Johanna / Kivivuori, Sanna-Maria / Meretoja, Atte

Infectious diseases (London, England)

2021  Volume 53, Issue 10, Page(s) 789–799

Abstract: ... described demographics, severity and case-fatality by sex of the first Covid-19 wave February-June 2020 ... healthcare (: Conclusions: Male sex associated with higher disease severity and case-fatality. Late ... overall mortality in Covid-19 in a population based setting with patients treated in specialized ...

Abstract Background: Men reportedly suffer from a more severe disease and higher mortality during the global SARS-CoV-2 (Covid-19) pandemic. We analysed sex differences in a low epidemic area with low overall mortality in Covid-19 in a population based setting with patients treated in specialized healthcare.
Methods: We entered all hospitalized laboratory-confirmed Covid-19 cases of all specialized healthcare hospitals of the Capital Province of Finland, into a population-based quality registry and described demographics, severity and case-fatality by sex of the first Covid-19 wave February-June 2020.
Results: Altogether 5471 patients (49% male) were identified. Patients hospitalized in the specialist healthcare (
Conclusions: Male sex associated with higher disease severity and case-fatality. Late presentation of male fatal cases could represent different treatment-seeking behaviour or disease progression by sex.
MeSH term(s) COVID-19 ; COVID-19 Testing ; Epidemics ; Female ; Hospitalization ; Humans ; Male ; Registries ; SARS-CoV-2 ; Severity of Illness Index
Language English
Publishing date 2021-06-08
Publishing country England
Document type Journal Article
ZDB-ID 2839775-7
ISSN 2374-4243 ; 2374-4235
ISSN (online) 2374-4243
ISSN 2374-4235
DOI 10.1080/23744235.2021.1936157
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