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  1. Article ; Online: Necrotizing pancreatitis with portal vein thrombosis in young patient with COVID-19.

    Alwaheed, Abrar J / Alalwan, Mohannad A / Aldakhlan, Hasan M / Albeladi, Feda H

    Journal of infection and public health

    2022  Volume 15, Issue 4, Page(s) 433–436

    Abstract: ... few cases reported with pancreatic injury were caused by COVID-19. In this paper, we report a young patient ... gastrointestinal symptoms were also reported in patients with COVID-19 infection. It has been found that the ACE2 ... presenting with acute necrotizing pancreatitis that is complicated with portal vein thrombosis and found ...

    Abstract The current pandemic of the novel coronavirus disease 2019 (COVID-19) originated in Wuhan, China in December 2019. The most common clinical manifestations are fever, fatigue, and cough. Other common symptoms include anorexia, chest tightness and shortness of breath. Extrapulmonary manifestations including gastrointestinal symptoms were also reported in patients with COVID-19 infection. It has been found that the ACE2 receptor of SARS-CoV-2 is expressed more in the pancreas than in the lungs. However, only few cases reported with pancreatic injury were caused by COVID-19. In this paper, we report a young patient presenting with acute necrotizing pancreatitis that is complicated with portal vein thrombosis and found to have COVID-19 infection.
    MeSH term(s) COVID-19/complications ; Humans ; Liver Diseases ; Pancreatitis, Acute Necrotizing/complications ; Pancreatitis, Acute Necrotizing/diagnosis ; Portal Vein ; SARS-CoV-2 ; Thrombosis
    Language English
    Publishing date 2022-03-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2467587-8
    ISSN 1876-035X ; 1876-0341
    ISSN (online) 1876-035X
    ISSN 1876-0341
    DOI 10.1016/j.jiph.2022.03.009
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  2. Article ; Online: COVID-19 in Cirrhotic Patients: Is Portal Vein Thrombosis a Potential Complication?

    Hassnine, Alshymaa A / Elsayed, Amr M

    Canadian journal of gastroenterology & hepatology

    2022  Volume 2022, Page(s) 5900468

    Abstract: ... patient in group B had PVT (2.3%) (: Conclusion: In cirrhotic patients infected with COVID-19 ... such as diabetes and hypertension. Portal vein thrombosis (PVT) is a rare venous thromboembolic disease occurring ... patients of the liver cirrhosis: (group A) 28 patients with liver cirrhosis infected with COVID-19, and 42 ...

    Abstract Introduction: Several studies have demonstrated that thromboembolic events increased in patients with coronavirus infection, usually occurring in elderly patients with severe illness, associated with comorbid diseases such as diabetes and hypertension. Portal vein thrombosis (PVT) is a rare venous thromboembolic disease occurring typically in patients with an underlying disease such as decompensated cirrhosis with or without hepatocellular carcinoma (HCC).
    Aim: To evaluate incidence of occurrence of acute PVT in cirrhotic patients infected with 2019 coronavirus disease (COVID-19).
    Methods: This cross-sectional, observational study involved 70 patients of the liver cirrhosis: (group A) 28 patients with liver cirrhosis infected with COVID-19, and 42 patients with liver cirrhosis as the control group matched for age and sex (group B). All patients were subjected to thorough medical history, routine investigations (complete blood count, liver, and renal function tests), imaging in the form of abdominal and Doppler ultrasonography to assess the presence of acute PVT, serum ferritin, D-dimer, C-reactive protein, and PCR of COVID-19 for group A only.
    Results: There was a significant difference between the two groups regarding Doppler ultrasound findings as 3 of the patients in group A had PVT (10.7%), 2 of them had HCC diagnosed by triphasic CT abdomen, and only 1 patient in group B had PVT (2.3%) (
    Conclusion: In cirrhotic patients infected with COVID-19, portal vein thrombosis may be a potential complication even in the absence of hepatocellular carcinoma; further prospective studies with longer follow-up may be needed.
    MeSH term(s) Aged ; COVID-19/complications ; Carcinoma, Hepatocellular/complications ; Cross-Sectional Studies ; Humans ; Liver Cirrhosis/complications ; Liver Neoplasms ; Portal Vein ; Prospective Studies ; Venous Thrombosis/epidemiology ; Venous Thrombosis/etiology
    Language English
    Publishing date 2022-03-26
    Publishing country Egypt
    Document type Journal Article ; Observational Study
    ZDB-ID 2762182-0
    ISSN 2291-2797 ; 1916-7237 ; 0835-7900
    ISSN (online) 2291-2797 ; 1916-7237
    ISSN 0835-7900
    DOI 10.1155/2022/5900468
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2360: Show issues Location:
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  3. Article ; Online: Portal vein thrombosis in patients with COVID-19: A systematic review.

    El-Hady, Hany Abdelfatah / Mahmoud Abd-Elwahab, El-Sayed / Mostafa-Hedeab, Gomaa / Shawky Elfarargy, Mohamed

    Asian journal of surgery

    2022  Volume 46, Issue 8, Page(s) 3017–3026

    Abstract: ... events. Thrombosis of the portal vein can result in portal hypertension and can extend ... Several studies have proven that COVID-19 is linked to a higher incidence of different thrombotic ... studies revealed an association between PVT and COVID-19. This review is structured according to PRISMA ...

    Abstract Several studies have proven that COVID-19 is linked to a higher incidence of different thrombotic events. Thrombosis of the portal vein can result in portal hypertension and can extend to the mesenteric vein resulting in intestinal ischemia. A search of PubMed, Web of Science, and Scopus for relevant studies revealed an association between PVT and COVID-19. This review is structured according to PRISMA guidelines. Thirty-three studies met the inclusion criteria. Twenty-nine case studies/series and four cohort/cross-sectional studies were included. Age at diagnosis was lower when compared to PVT due to cirrhosis. In cohort/cross-sectional studies, males comprised 54.83% of subjects, whereas in case reports/series, males comprised 62.1%. Obesity, asthma, hypertension, and diabetes were the most common comorbidities identified. The majority of the thrombotic events occurred within two weeks. The treatment aimed to prevent thrombus progression and improve recanalization. According to the evidence, early intervention prevents the poor prognosis of intestinal ischemia and its propagation.
    MeSH term(s) Male ; Humans ; Female ; Portal Vein/pathology ; Cross-Sectional Studies ; Anticoagulants ; COVID-19/complications ; Venous Thrombosis/epidemiology ; Venous Thrombosis/etiology ; Venous Thrombosis/therapy ; Thrombosis/etiology ; Liver Cirrhosis/complications ; Ischemia/pathology
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2022-11-11
    Publishing country Netherlands
    Document type Systematic Review ; Journal Article ; Review
    ZDB-ID 1068461-x
    ISSN 0219-3108 ; 1015-9584
    ISSN (online) 0219-3108
    ISSN 1015-9584
    DOI 10.1016/j.asjsur.2022.11.002
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    Zs.B 2831: Show issues Location:
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  4. Article ; Online: Portal Vein Thrombosis in a Patient With COVID-19.

    Ofosu, Andrew / Ramai, Daryl / Novikov, Anastasia / Sushma, Venugopal

    The American journal of gastroenterology

    2020  Volume 115, Issue 9, Page(s) 1545–1546

    MeSH term(s) Betacoronavirus ; COVID-19 ; Computed Tomography Angiography ; Coronavirus Infections/complications ; Coronavirus Infections/epidemiology ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/epidemiology ; Portal Vein ; SARS-CoV-2 ; Thrombolytic Therapy/methods ; Venous Thrombosis/diagnosis ; Venous Thrombosis/drug therapy ; Venous Thrombosis/etiology
    Keywords covid19
    Language English
    Publishing date 2020-07-21
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 390122-1
    ISSN 1572-0241 ; 0002-9270
    ISSN (online) 1572-0241
    ISSN 0002-9270
    DOI 10.14309/ajg.0000000000000781
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  5. Article: Simultaneous acute portal vein thrombosis and ST elevation myocardial infarction in a Covid-19 patient - Case report.

    Nournia, Ensieh / Abbasi, Hamid / Bazrafshan, Maziar

    Heliyon

    2023  Volume 9, Issue 11, Page(s) e22301

    Abstract: ... years-old Covid-19 patient with mild symptoms who was admitted to the hospital with simultaneous ... The patient was diagnosed with Covid-19 two weeks before admission to the ICU. A 12-lead electrocardiogram ... Background: Covid-19 infected patients without any risk factors and family history of a thrombotic ...

    Abstract Background: Covid-19 infected patients without any risk factors and family history of a thrombotic event can be still at risks of developing thrombotic and/or other Covid-19-related complications, and therefore, there is a substantial need to study such cases.
    Case presentation: In this study, we present a 60-years-old Covid-19 patient with mild symptoms who was admitted to the hospital with simultaneous arterial and venous thrombotic event, with chief complaint of chest pain and vague abdominal pain. The patient was diagnosed with Covid-19 two weeks before admission to the ICU. A 12-lead electrocardiogram revealed pathologic Q-wave ST-segment elevation and T-wave inversion in II, III, aVF, and T inversion in V5 and V6. Quantitative troponin was elevated which confirmed inferior ST-elevation MI. Abdominal color Doppler sonography and CT scan with contrast demonstrated an absent flow in the portal vein and thrombosis. A chest CT scan illustrated a normal pattern. We started IV unfractionated heparin (UFH), dual antiplatelet, beta-blocker, statin, intravenous nitrate, and angiotensin-converting enzyme inhibitor. Coronary angiography showed the right coronary artery was totally cut off at the proximal part.Here we report three main un-common characteristics associated with our patient compared to other similar studies. First, the thrombotic event in our case occurred without pulmonary involvement and the patient only had a flu-like symptom two weeks before admission. The second main difference is that the patient's arterial and venous thrombotic events had simultaneously happened, which is not common in most cases. Patient presented simultaneous portal vein thrombosis and recent ST-segment elevation Myocardial Infarction (MI). Finally, both MI and portal vein thrombosis symptoms were subtle and confusing, which could cause misdiagnosis. A post two-weeks color Doppler sonography follow-up showed portal vein thrombosis recanalization and myocardial perfusion scan had no viability and reversible ischemia in RCA territory.
    Conclusions: This report addresses that a cautious diagnosis of Covid-19 at the time of admission can play a vital role in preventing cardiovascular events; where even asymptomatic to mildly infected patients could be still at higher risks of developing clinical complications (e.g., thrombotic events).
    Language English
    Publishing date 2023-11-17
    Publishing country England
    Document type Case Reports
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e22301
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  6. Article ; Online: Portal vein thrombosis in a patient with COVID-19.

    Franco-Moreno, A / Piniella-Ruiz, E / Montoya-Adarraga, J / Ballano-Franco, C / Alvarez-Miguel, F / Peinado-Martinez, C / Landete-Hernandez, E / Saez-Vaquero, T / Ulla-Anes, M / Torres-Macho, J

    Thrombosis research

    2020  Volume 194, Page(s) 150–152

    Keywords covid19
    Language English
    Publishing date 2020-06-13
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 121852-9
    ISSN 1879-2472 ; 0049-3848
    ISSN (online) 1879-2472
    ISSN 0049-3848
    DOI 10.1016/j.thromres.2020.06.019
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 863: Show issues Location:
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  7. Article: Portal Vein Thrombosis and Splenic Infarction in a COVID-19 Patient.

    Rehman, Abdul / Thoppil, Anoop Jose / Wallach, Sara L

    Cureus

    2021  Volume 13, Issue 8, Page(s) e16843

    Abstract: ... when it leads to thrombosis in unusual sites such as the portal vein. Another important question that remains ... COVID-19 is a novel viral infection that primarily affects the lungs and runs the gamut from a mild ... addresses both these questions with an intriguing patient who presented with abdominal pain as the chief ...

    Abstract COVID-19 is a novel viral infection that primarily affects the lungs and runs the gamut from a mild, self-limiting, febrile illness to respiratory failure and death. It manifested as a global pandemic in 2020 and has since claimed millions of lives. Only a few months into this pandemic, it became evident that the viral infection leads to a hypercoagulable state. Anticoagulants became a standard and important part of therapy while d-dimer became a useful test to guide the choice of the anticoagulant (therapeutic vs prophylactic Lovenox). What remains unclear is how viral pneumonia can cause hypercoagulability, especially when it leads to thrombosis in unusual sites such as the portal vein. Another important question that remains unanswered is the duration of anticoagulation after discharge in the outpatient setting. Our case report addresses both these questions with an intriguing patient who presented with abdominal pain as the chief complaint in the absence of any respiratory symptoms whatsoever.
    Language English
    Publishing date 2021-08-02
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.16843
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  8. Article: Coexisting portal vein thrombosis and aortic thrombosis in a patient with COVID-19: A case report and literature review.

    Akella, Ramya / Raj, Rishi / Kannan, Lakshmi / Jacob, Aasems

    IDCases

    2022  Volume 28, Page(s) e01509

    Abstract: ... following mild COVID-19. Incidentally, the patient was also noted to have aortic thrombosis. The patient was ... onset abdominal pain and was diagnosed with portal vein thrombosis and splenic infarct two weeks ... The Coronavirus Disease 2019 (COVID-19) pandemic has rapidly progressed, resulting in significant ...

    Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has rapidly progressed, resulting in significant global morbidity and mortality. Predominantly affecting the respiratory tract, it has been found to be associated with extrapulmonary manifestations such as coagulopathies. We hereby report a case of an elderly man with no predisposing risk factors or history of hypercoagulable disorder who presented with acute onset abdominal pain and was diagnosed with portal vein thrombosis and splenic infarct two weeks following mild COVID-19. Incidentally, the patient was also noted to have aortic thrombosis. The patient was treated with therapeutic anticoagulation with complete resolution in his symptoms. Our case highlights a high risk of coagulopathy following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
    Language English
    Publishing date 2022-05-18
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2745454-X
    ISSN 2214-2509
    ISSN 2214-2509
    DOI 10.1016/j.idcr.2022.e01509
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  9. Article ; Online: Necrotizing pancreatitis with portal vein thrombosis in young patient with COVID-19

    Abrar J. Alwaheed / Mohannad A. Alalwan / Hasan M. Aldakhlan / Feda H. Albeladi

    Journal of Infection and Public Health, Vol 15, Iss 4, Pp 433-

    2022  Volume 436

    Abstract: ... few cases reported with pancreatic injury were caused by COVID-19. In this paper, we report a young patient ... gastrointestinal symptoms were also reported in patients with COVID-19 infection. It has been found that the ACE2 ... presenting with acute necrotizing pancreatitis that is complicated with portal vein thrombosis and found ...

    Abstract The current pandemic of the novel coronavirus disease 2019 (COVID-19) originated in Wuhan, China in December 2019. The most common clinical manifestations are fever, fatigue, and cough. Other common symptoms include anorexia, chest tightness and shortness of breath. Extrapulmonary manifestations including gastrointestinal symptoms were also reported in patients with COVID-19 infection. It has been found that the ACE2 receptor of SARS-CoV-2 is expressed more in the pancreas than in the lungs. However, only few cases reported with pancreatic injury were caused by COVID-19. In this paper, we report a young patient presenting with acute necrotizing pancreatitis that is complicated with portal vein thrombosis and found to have COVID-19 infection.
    Keywords Thrombosis ; COVID-19 ; Acute pancreatitis ; Portal vein thrombosis ; Infectious and parasitic diseases ; RC109-216 ; Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Gastric ischemia and portal vein thrombosis in a COVID-19-infected patient.

    Low, See-Wei / Swanson, Karen L / McCain, Josiah D / Sen, Ayan / Kawashima, Akira / Pasha, Shabana F

    Endoscopy

    2020  Volume 52, Issue 12, Page(s) E465–E466

    MeSH term(s) COVID-19/complications ; Endoscopy, Gastrointestinal ; Gastric Mucosa/blood supply ; Humans ; Ischemia/diagnostic imaging ; Ischemia/virology ; Male ; Middle Aged ; Portal Vein ; SARS-CoV-2 ; Tomography, X-Ray Computed ; Venous Thrombosis/diagnostic imaging ; Venous Thrombosis/virology
    Keywords covid19
    Language English
    Publishing date 2020-09-02
    Publishing country Germany
    Document type Case Reports ; Journal Article ; Video-Audio Media
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/a-1230-3357
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    Zs.MO 162: Show issues

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