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  1. Article ; Online: Longitudinally extensive transverse myelitis following acute COVID-19 infection.

    Fumery, Thibault / Baudar, Coline / Ossemann, Michel / London, Frédéric

    Multiple sclerosis and related disorders

    2020  Volume 48, Page(s) 102723

    Abstract: ... of a 38-year-old woman presenting with longitudinally extensive transverse myelitis, revealed by bilateral ... Corona Virus Disease 2019 (COVID-19) is a new illness caused by a novel coronavirus ... after she had been diagnosed with COVID-19. ...

    Abstract Corona Virus Disease 2019 (COVID-19) is a new illness caused by a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). With the increasing number of confirmed cases and the accumulating clinical data, a broad spectrum of neurological complications has been reported in the literature, including encephalopathy, stroke, Guillain-Barré syndrome, meningo-encephalitis, acute necrotizing hemorrhagic encephalopathy, and inflammatory central nervous system syndromes. Here, we describe the case of a 38-year-old woman presenting with longitudinally extensive transverse myelitis, revealed by bilateral lower limb weakness, decreased sensation below the Th4 level and urinary retention, and occuring 15 days after she had been diagnosed with COVID-19.
    MeSH term(s) Adult ; COVID-19/complications ; Female ; Humans ; Myelitis, Transverse/etiology ; Myelitis, Transverse/physiopathology
    Language English
    Publishing date 2020-12-25
    Publishing country Netherlands
    Document type Case Reports ; Letter
    ZDB-ID 2645330-7
    ISSN 2211-0356 ; 2211-0348
    ISSN (online) 2211-0356
    ISSN 2211-0348
    DOI 10.1016/j.msard.2020.102723
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: A Case of Longitudinally Extensive Transverse Myelitis Following COVID-19 Infection.

    Gummadi, Jyotsna / Bhattachan, Meika / Nanjundappa, Athmananda

    Cureus

    2023  Volume 15, Issue 10, Page(s) e47604

    Abstract: One of the rare complications following acute COVID-19 infection is acute transverse myelitis (ATM ... cerebrospinal fluid (CSF) and laboratory findings pointed toward LETM as a complication of COVID-19 infection over ... With only a few cases of ATM reported in the literature, an addition of longitudinally extensive transverse ...

    Abstract One of the rare complications following acute COVID-19 infection is acute transverse myelitis (ATM). With only a few cases of ATM reported in the literature, an addition of longitudinally extensive transverse myelitis (LETM) diagnosed in our patient would underscore the complexity and diversity of neurological manifestations associated with this viral illness. A 54-year-old patient presented to the emergency department with fever, shortness of breath, nausea and vomiting. The patient's nasopharyngeal swab for COVID-19 polymerase chain reaction (PCR) resulted positive. Few days later, the patient developed bilateral upper, lower extremities weakness, back pain, urinary retention and dysphagia. Subsequently, the clinical presentation, MRI, cerebrospinal fluid (CSF) and laboratory findings pointed toward LETM as a complication of COVID-19 infection over other differentials. The aggressiveness of this disease necessitated high-dose steroids and plasmapheresis, pain control medication and rehabilitation which led to a slight improvement in the neurological symptoms at the time of discharge to the rehabilitation facility.
    Language English
    Publishing date 2023-10-24
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.47604
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Longitudinally extensive transverse myelitis with anti-myelin oligodendrocyte glycoprotein antibodies following SARS-CoV-2 infection.

    Dias da Costa, Mariana / Leal Rato, Miguel / Cruz, Diana / Valadas, Anabela / Antunes, Ana Patrícia / Albuquerque, Luísa

    Journal of neuroimmunology

    2021  Volume 361, Page(s) 577739

    Abstract: ... MRI documented a longitudinally extensive transverse myelitis and further investigation was ... We report the case of a patient with symptoms of myelopathy following acute SARS-CoV-2 infection ... COVID-19 neurological syndromes, and documents a very significant improvement to long-term oral ...

    Abstract We report the case of a patient with symptoms of myelopathy following acute SARS-CoV-2 infection. MRI documented a longitudinally extensive transverse myelitis and further investigation was unremarkable with the exception of positivity for MOG-IgG in serum. This report extends the spectrum of post-COVID-19 neurological syndromes, and documents a very significant improvement to long-term oral corticosteroid therapy in this setting. Further prospective studies are needed to establish the risk of recurrence in this subset of patients.
    MeSH term(s) Adult ; Autoantibodies/immunology ; Autoantigens/immunology ; COVID-19/complications ; COVID-19/immunology ; Humans ; Male ; Myelin-Oligodendrocyte Glycoprotein/immunology ; Myelitis, Transverse/immunology ; Myelitis, Transverse/pathology ; Myelitis, Transverse/virology ; SARS-CoV-2
    Chemical Substances Autoantibodies ; Autoantigens ; MOG protein, human ; Myelin-Oligodendrocyte Glycoprotein
    Language English
    Publishing date 2021-10-05
    Publishing country Netherlands
    Document type Case Reports ; Journal Article
    ZDB-ID 8335-5
    ISSN 1872-8421 ; 0165-5728
    ISSN (online) 1872-8421
    ISSN 0165-5728
    DOI 10.1016/j.jneuroim.2021.577739
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Concurrent Longitudinally Extensive Transverse Myelitis and Guillain-Barré Syndrome in a Child Secondary to COVID-19 Infection: A Severe Neuroimmunologic Complication of COVID-19.

    Khera, Daisy / Didel, Siyaram / Panda, Samhita / Tiwari, Sarbesh / Singh, Kuldeep

    The Pediatric infectious disease journal

    2021  Volume 40, Issue 6, Page(s) e236–e239

    Abstract: ... of longitudinally extensive transverse myelitis (LETM) with enhancing cauda equina nerve roots, suggesting ... and we need to suspect these diagnoses in the cases with COVID-19 infection in compatible cases ... This is probably the first pediatric case with concurrent GBS and LETM secondary to COVID-19 infection. ...

    Abstract Neurologic manifestation of coronavirus disease 2019 (COVID-19) in children is evolving with time. We are reporting a young girl who presented to us with acute febrile illness followed by acute onset severe flaccid paralysis requiring prolonged intensive care unit stay and ventilator support. She was evaluated extensively and found to be positive for COVID serology, and neuroimaging revealed features of longitudinally extensive transverse myelitis (LETM) with enhancing cauda equina nerve roots, suggesting Guillain-Barré Syndrome (GBS). She failed to respond to immune suppressive therapy and needed plasma exchange for recovery. Like other common viral illnesses, COVID-19 can also act as a trigger for GBS-like illness and LETM, and we need to suspect these diagnoses in the cases with COVID-19 infection in compatible cases. This is probably the first pediatric case with concurrent GBS and LETM secondary to COVID-19 infection.
    MeSH term(s) COVID-19/complications ; COVID-19/diagnosis ; COVID-19/immunology ; COVID-19 Serological Testing ; Child ; Female ; Guillain-Barre Syndrome/immunology ; Guillain-Barre Syndrome/virology ; Humans ; Myelitis, Transverse/immunology ; SARS-CoV-2/isolation & purification
    Language English
    Publishing date 2021-04-23
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 392481-6
    ISSN 1532-0987 ; 0891-3668
    ISSN (online) 1532-0987
    ISSN 0891-3668
    DOI 10.1097/INF.0000000000003124
    Database MEDical Literature Analysis and Retrieval System OnLINE

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