Article ; Online: Characteristics and Clinical Course of Adult in Patients with SARS-CoV-2 Pneumonia at High Altitude.
2021 Volume 2021, Page(s) 5590879
Abstract: ... of adult patients with laboratory-confirmed SARS-CoV-2 pneumonia. Demographic, clinical, and treatment data ... In this study of in-hospital patients with SARS-CoV-2 pneumonia living at high altitude, frequency of death was ... use of invasive mechanical ventilation in hospitalized patients with SARS-CoV-2 pneumonia in a high ...
| Abstract | Background: SARS-CoV-2 has spread worldwide with different dynamics in each region. We aimed to describe the clinical characteristics and to explore risk factors of death, critical care admission, and use of invasive mechanical ventilation in hospitalized patients with SARS-CoV-2 pneumonia in a high-altitude population living in Bogotá, Colombia. Methods: We conducted a concurrent cohort study of adult patients with laboratory-confirmed SARS-CoV-2 pneumonia. Demographic, clinical, and treatment data were extracted from electronic records. Univariate and multivariable methods were performed to investigate the relationship between each variable and outcomes at 28 days of follow-up. Results: 377 adults (56.8% male) were included in the study, of whom 85 (22.6%) died. Nonsurvivors were older on average than survivors (mean age, 56.7 years [SD 15.8] vs. 70.1 years [SD 13.9]; Conclusions: In this study of in-hospital patients with SARS-CoV-2 pneumonia living at high altitude, frequency of death was similar to what has been reported. ICU admission and use of invasive mechanical ventilation were high. Risk factors as older age, ICU admission, and arterial pH were associated with mortality. |
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| MeSH term(s) | Adult ; Aged ; Altitude ; COVID-19/complications ; COVID-19/mortality ; COVID-19/therapy ; Cohort Studies ; Colombia ; Critical Care ; Female ; Hospital Mortality ; Hospitalization ; Humans ; Male ; Middle Aged ; Respiration, Artificial ; Risk Factors | |||||
| Language | English | |||||
| Publishing date | 2021-06-08 | |||||
| Publishing country | Egypt | |||||
| Document type | Journal Article | |||||
| ZDB-ID | 1213103-9 | |||||
| ISSN | 1916-7245 ; 1198-2241 | |||||
| ISSN (online) | 1916-7245 | |||||
| ISSN | 1198-2241 | |||||
| DOI | 10.1155/2021/5590879 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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