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  1. Article ; Online: Symptoms in patients with asthma infected by SARS-CoV-2.

    Garcia-Pachon, Eduardo / Ruiz-Alcaraz, Sandra / Baeza-Martinez, Carlos / Zamora-Molina, Lucia / Soler-Sempere, Maria J / Padilla-Navas, Isabel / Grau-Delgado, Justo

    Respiratory medicine

    2021  Volume 185, Page(s) 106495

    Abstract: ... with SARS-CoV-2 is unknown. We aimed to investigate the symptoms presented in patients with asthma ... who became infected with SARS-CoV-2.: Methods and results: All patients over 14 years of age who tested ... positive for SARS-CoV-2 (by RT-PCR) were included (n = 2995). In patients with asthma (n = 77, 2.6%; 44 ...

    Abstract Introduction: Organ tropism of SARS-CoV-2 to the respiratory tract could potentially aggravate asthma. The susceptibility of patients with asthma to develop an exacerbation when they are infected with SARS-CoV-2 is unknown. We aimed to investigate the symptoms presented in patients with asthma who became infected with SARS-CoV-2.
    Methods and results: All patients over 14 years of age who tested positive for SARS-CoV-2 (by RT-PCR) were included (n = 2995). In patients with asthma (n = 77, 2.6%; 44 females), symptoms, therapy and phenotype were recorded. Seventeen (22%) patients had mild asthma, 55 (71%) moderate and five severe (6%). Twenty-six patients with asthma (34%) were asymptomatic, 34 (44%) developed symptoms but did not require hospital admission, and 17 (22%) were hospitalised. One patient was admitted because of asthma exacerbation without pneumonia or other symptoms. Ten patients (13%) had wheezes (six with pneumonia). Comparison of wheezing between patients with non-T2 asthma and the rest of the patients was statistically significant, (p < 0.001).
    Conclusions: SARS-CoV-2 infection is not a significant cause of asthma exacerbation, although some patients may present wheezing, especially in cases of pneumonia. The severity of asthma does not seem to be associated with symptoms of the disease.
    MeSH term(s) Adult ; Asthma/diagnosis ; Asthma/epidemiology ; COVID-19/epidemiology ; Comorbidity ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; SARS-CoV-2 ; Severity of Illness Index
    Language English
    Publishing date 2021-06-08
    Publishing country England
    Document type Journal Article ; Observational Study
    ZDB-ID 1003348-8
    ISSN 1532-3064 ; 0954-6111
    ISSN (online) 1532-3064
    ISSN 0954-6111
    DOI 10.1016/j.rmed.2021.106495
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: COVID-19 in patients presenting with malaria-like symptoms at a primary healthcare facility in Accra, Ghana.

    Asamoah, Issabella / Adusei-Poku, Mildred / Vandyck-Sey, Priscilla / Steele-Dadzie, Allen / Kuffour, Atta Senior / Turkson, Albert / Asante, Ivy Asantewaa / Addo-Osafo, Kantanka / Mohktar, Quaneeta / Adu, Bright / Afrane, Yaw A / Sagoe, Kwamena W C

    PloS one

    2024  Volume 19, Issue 2, Page(s) e0298088

    Abstract: ... in 23 of 25 SARS-CoV-2 positives with CT values below 30. Headache was the most common symptom presented ... CoV-2 using SARS-CoV-2 antigen test and Real-time PCR, respectively. The plasma and whole blood were ... also used for COVID-19 antibody testing and full blood counts using hematological analyser. SARS-CoV-2 ...

    Abstract Background: Malaria is a common and severe public health problem in Ghana and largely responsible for febrile symptoms presented at health facilities in the country. Other infectious diseases, including COVID-19, may mimic malaria due to their shared non-specific symptoms such as fever and headache thus leading to misdiagnosis. This study therefore investigated COVID-19 among patients presenting with malaria-like symptoms at Korle-Bu Polyclinic, Accra, Ghana.
    Methods: This study enrolled 300 patients presenting with malaria-like symptoms aged ≥18yrs. After consent was obtained from study patients, two to three millilitres of whole blood, nasopharyngeal and oropharyngeal swab samples, were collected for screening of Plasmodium falciparum using malaria rapid diagnostic test, microscopy and nested PCR, and SARS-CoV-2 using SARS-CoV-2 antigen test and Real-time PCR, respectively. The plasma and whole blood were also used for COVID-19 antibody testing and full blood counts using hematological analyser. SARS-CoV-2 whole genome sequencing was performed using MinIon sequencing.
    Results: The prevalence of malaria by microscopy, RDT and nested PCR were 2.3%, 2.3% and 2.7% respectively. The detection of SARS-CoV-2 by COVID-19 Rapid Antigen Test and Real-time PCR were 8.7% and 20% respectively. The Delta variant was reported in 23 of 25 SARS-CoV-2 positives with CT values below 30. Headache was the most common symptom presented by study participants (95%). Comorbidities reported were hypertension, asthma and diabetes. One hundred and thirteen (37.8%) of the study participants had prior exposure to SARS CoV-2 and (34/51) 66.7% of Astrazeneca vaccinated patients had no IgG antibody.
    Conclusion: It may be difficult to use clinical characteristics to distinguish between patients with COVID-19 having malaria-like symptoms. Detection of IgM using RDTs may be useful in predicting CT values for SARS-CoV-2 real-time PCR and therefore transmission.
    MeSH term(s) Humans ; COVID-19/diagnosis ; COVID-19/epidemiology ; SARS-CoV-2/genetics ; COVID-19 Testing ; Ghana/epidemiology ; Malaria/diagnosis ; Malaria/epidemiology ; Real-Time Polymerase Chain Reaction ; Headache ; Primary Health Care ; Sensitivity and Specificity
    Language English
    Publishing date 2024-02-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0298088
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: In COVID-19 Patients, the Identified Gastrointestinal Symptoms in Tertiary Care Center of India.

    Murugesan, Malarvizhi / Govindarajan, Ramkumar / Prakash, Lakshmi / Murugan, Chandra Kumar / Jasmine, J Janifer / Krishnasamy, Narayanasamy

    Euroasian journal of hepato-gastroenterology

    2022  Volume 12, Issue 1, Page(s) 24–30

    Abstract: ... of symptoms that are first expressed after being infected with the SARS-CoV-2 virus. Several studies showed ... of a tertiary care center were screened for 3 months. Patients were confirmed positive for SARS-CoV-2 virus ... Among 956 COVID-19 patients, GI symptoms were loss of smell (29.2%), loss of taste (26.4%) for 3 days ...

    Abstract Aim: This study aimed to assess the demographic details of coronavirus disease-2019 (COVID-19) patients, their comorbid conditions, preexisting illnesses such as tuberculosis (TB), the prevalence of gastrointestinal (GI) symptoms, duration of GI symptoms, gender-wise distribution of GI symptoms, age-wise distribution of GI symptoms, lab investigation, and computed tomography (CT) scanning was done to record the grading.
    Materials and methods: In total, 956 COVID-19 patients admitted to an isolation ward of a tertiary care center were screened for 3 months. Patients were confirmed positive for SARS-CoV-2 virus by real-time polymerase chain reaction (RT-PCR) test with a throat swab. Patient's age, demographic details, preexisting illness, and GI symptoms such as fever, impairment of appetite, loss of taste, loss of smell, hiccups, nausea, vomiting, diarrhea, abdominal pain, symptom's duration, history of chronic drug intake, biological markers, CT scanning, and comorbidities were recorded. Based on the provided protocol, standard care management was given to the admitted COVID-19 patients.Statistical analysis was performed using SPSS version 20.0. Frequencies with percentages, median (min, max), Chi-square test, and Mann-Whitney
    Results: In our prospective study of 956 COVID-19 hospitalized patients, details were analyzed and the results are: the median age was 45 years, 70% of male, 60% were above 35 years, comorbidities like diabetes present in 42%, hypertension in 36%, asthma in 8%, cardiovascular diseases (CVD) in 5%, and history of chronic drug intake in 21%.Among 956 COVID-19 patients, GI symptoms were loss of smell (29.2%), loss of taste (26.4%) for 3 days; nausea (10%), vomiting (7.1%), abdominal pain (12.7%), and fever (42.5%) were observed for 2 days among the 36-45 years of age-group; and the loss of appetite (19%) for 3 days among the age-group of 46-55 years.The loss of appetite (23.7 vs 16.9%) (
    Conclusion: In conclusion, GI symptoms are the onset of symptoms that are first expressed after being infected with the SARS-CoV-2 virus. Several studies showed the GI symptoms but did not analyze the age and gender that are risk factors for any disease, but our study showed all GI symptoms and their association with age and gender, which will shed light for our clinicians for early symptom identification, diagnosis, and appropriate treatment.
    How to cite this article: Murugesan M, Govindarajan R, Prakash L,
    Language English
    Publishing date 2022-08-14
    Publishing country India
    Document type Journal Article
    ZDB-ID 2651614-7
    ISSN 2231-5128 ; 2231-5047
    ISSN (online) 2231-5128
    ISSN 2231-5047
    DOI 10.5005/jp-journals-10018-1371
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Variation in global COVID-19 symptoms by geography and by chronic disease: A global survey using the COVID-19 Symptom Mapper.

    Kadirvelu, Balasundaram / Burcea, Gabriel / Quint, Jennifer K / Costelloe, Ceire E / Faisal, A Aldo

    EClinicalMedicine

    2022  Volume 45, Page(s) 101317

    Abstract: ... should focus on symptom profile variation in the emerging variants of the SARS-CoV-2 virus. This is crucial ... 19 spread and put patients with chronic diseases at a greater risk of infection. Future work ... COVID-19 positive responders with asthma (25.3% vs. 13.7%, p=7e-6) were more likely to report shortness ...

    Abstract Background: COVID-19 is typically characterised by a triad of symptoms: cough, fever and loss of taste and smell, however, this varies globally. This study examines variations in COVID-19 symptom profiles based on underlying chronic disease and geographical location.
    Methods: Using a global online symptom survey of 78,299 responders in 190 countries between 09/04/2020 and 22/09/2020, we conducted an exploratory study to examine symptom profiles associated with a positive COVID-19 test result by country and underlying chronic disease (single, co- or multi-morbidities) using statistical and machine learning methods.
    Findings: From the results of 7980 COVID-19 tested positive responders, we find that symptom patterns differ by country. For example, India reported a lower proportion of headache (22.8% vs 47.8%, p<1e-13) and itchy eyes (7.3% vs. 16.5%, p=2e-8) than other countries. As with geographic location, we find people differed in their reported symptoms if they suffered from specific chronic diseases. For example, COVID-19 positive responders with asthma (25.3% vs. 13.7%, p=7e-6) were more likely to report shortness of breath compared to those with no underlying chronic disease.
    Interpretation: We have identified variation in COVID-19 symptom profiles depending on geographic location and underlying chronic disease. Failure to reflect this symptom variation in public health messaging may contribute to asymptomatic COVID-19 spread and put patients with chronic diseases at a greater risk of infection. Future work should focus on symptom profile variation in the emerging variants of the SARS-CoV-2 virus. This is crucial to speed up clinical diagnosis, predict prognostic outcomes and target treatment.
    Funding: We acknowledge funding to AAF by a UKRI Turing AI Fellowship and to CEC by a personal NIHR Career Development Fellowship (grant number NIHR-2016-090-015). JKQ has received grants from The Health Foundation, MRC, GSK, Bayer, BI, Asthma UK-British Lung Foundation, IQVIA, Chiesi AZ, and Insmed. This work is supported by BREATHE - The Health Data Research Hub for Respiratory Health [MC_PC_19004]. BREATHE is funded through the UK Research and Innovation Industrial Strategy Challenge Fund and delivered through Health Data Research UK. Imperial College London is grateful for the support from the Northwest London NIHR Applied Research Collaboration. The views expressed in this publication are those of the authors and not necessarily those of the NIHR or the Department of Health and Social Care.
    Language English
    Publishing date 2022-03-06
    Publishing country England
    Document type Journal Article
    ISSN 2589-5370
    ISSN (online) 2589-5370
    DOI 10.1016/j.eclinm.2022.101317
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Asthma phenotypes, associated comorbidities, and long-term symptoms in COVID-19.

    Eggert, Lauren E / He, Ziyuan / Collins, William / Lee, Alexandra S / Dhondalay, Gopal / Jiang, Shirley Y / Fitzpatrick, Jessica / Snow, Theo T / Pinsky, Benjamin A / Artandi, Maja / Barman, Linda / Puri, Rajan / Wittman, Richard / Ahuja, Neera / Blomkalns, Andra / O'Hara, Ruth / Cao, Shu / Desai, Manisha / Sindher, Sayantani B /
    Nadeau, Kari / Chinthrajah, R Sharon

    Allergy

    2021  Volume 77, Issue 1, Page(s) 173–185

    Abstract: ... symptoms.: Results: 168,190 patients underwent SARS-CoV-2 testing, and 6,976 (4.15%) tested positive ... for hospitalization or severe disease from SARS-CoV-2.: Methods: All patients over 28 days old testing positive ... 40). Among SARS-CoV-2-positive asthmatics, allergic asthma lowered the risk of hospitalization and ...

    Abstract Background: It is unclear whether asthma and its allergic phenotype are risk factors for hospitalization or severe disease from SARS-CoV-2.
    Methods: All patients over 28 days old testing positive for SARS-CoV-2 between March 1 and September 30, 2020, were retrospectively identified and characterized through electronic analysis at Stanford. A sub-cohort was followed prospectively to evaluate long-term COVID-19 symptoms.
    Results: 168,190 patients underwent SARS-CoV-2 testing, and 6,976 (4.15%) tested positive. In a multivariate analysis, asthma was not an independent risk factor for hospitalization (OR 1.12 [95% CI 0.86, 1.45], p = .40). Among SARS-CoV-2-positive asthmatics, allergic asthma lowered the risk of hospitalization and had a protective effect compared with non-allergic asthma (OR 0.52 [0.28, 0.91], p = .026); there was no association between baseline medication use as characterized by GINA and hospitalization risk. Patients with severe COVID-19 disease had lower eosinophil levels during hospitalization compared with patients with mild or asymptomatic disease, independent of asthma status (p = .0014). In a patient sub-cohort followed longitudinally, asthmatics and non-asthmatics had similar time to resolution of COVID-19 symptoms, particularly lower respiratory symptoms.
    Conclusions: Asthma is not a risk factor for more severe COVID-19 disease. Allergic asthmatics were half as likely to be hospitalized with COVID-19 compared with non-allergic asthmatics. Lower levels of eosinophil counts (allergic biomarkers) were associated with a more severe COVID-19 disease trajectory. Recovery was similar among asthmatics and non-asthmatics with over 50% of patients reporting ongoing lower respiratory symptoms 3 months post-infection.
    MeSH term(s) Asthma/diagnosis ; Asthma/epidemiology ; COVID-19 ; COVID-19 Testing ; Humans ; Phenotype ; Retrospective Studies ; SARS-CoV-2
    Language English
    Publishing date 2021-06-19
    Publishing country Denmark
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 391933-x
    ISSN 1398-9995 ; 0105-4538
    ISSN (online) 1398-9995
    ISSN 0105-4538
    DOI 10.1111/all.14972
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Variation in global COVID-19 symptoms by geography and by chronic disease

    Balasundaram Kadirvelu / Gabriel Burcea / Jennifer K. Quint / Ceire E. Costelloe / A. Aldo Faisal

    EClinicalMedicine, Vol 45, Iss , Pp 101317- (2022)

    A global survey using the COVID-19 Symptom Mapper

    2022  

    Abstract: ... should focus on symptom profile variation in the emerging variants of the SARS-CoV-2 virus. This is crucial ... to asymptomatic COVID-19 spread and put patients with chronic diseases at a greater risk of infection. Future work ... chronic diseases. For example, COVID-19 positive responders with asthma (25.3% vs. 13.7%, p=7e-6) were more likely ...

    Abstract Summary: Background: COVID-19 is typically characterised by a triad of symptoms: cough, fever and loss of taste and smell, however, this varies globally. This study examines variations in COVID-19 symptom profiles based on underlying chronic disease and geographical location. Methods: Using a global online symptom survey of 78,299 responders in 190 countries between 09/04/2020 and 22/09/2020, we conducted an exploratory study to examine symptom profiles associated with a positive COVID-19 test result by country and underlying chronic disease (single, co- or multi-morbidities) using statistical and machine learning methods. Findings: From the results of 7980 COVID-19 tested positive responders, we find that symptom patterns differ by country. For example, India reported a lower proportion of headache (22.8% vs 47.8%, p<1e-13) and itchy eyes (7.3% vs. 16.5%, p=2e-8) than other countries. As with geographic location, we find people differed in their reported symptoms if they suffered from specific chronic diseases. For example, COVID-19 positive responders with asthma (25.3% vs. 13.7%, p=7e-6) were more likely to report shortness of breath compared to those with no underlying chronic disease. Interpretation: We have identified variation in COVID-19 symptom profiles depending on geographic location and underlying chronic disease. Failure to reflect this symptom variation in public health messaging may contribute to asymptomatic COVID-19 spread and put patients with chronic diseases at a greater risk of infection. Future work should focus on symptom profile variation in the emerging variants of the SARS-CoV-2 virus. This is crucial to speed up clinical diagnosis, predict prognostic outcomes and target treatment. Funding: We acknowledge funding to AAF by a UKRI Turing AI Fellowship and to CEC by a personal NIHR Career Development Fellowship (grant number NIHR-2016-090-015). JKQ has received grants from The Health Foundation, MRC, GSK, Bayer, BI, Asthma UK-British Lung Foundation, IQVIA, Chiesi AZ, and Insmed. This ...
    Keywords COVID-19 ; COVID-19 symptoms ; COVID symptoms mapper ; COVID symptoms survey ; COVID symptom profile ; Comorbidities ; Medicine (General) ; R5-920
    Subject code 360
    Language English
    Publishing date 2022-03-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Persistent cough and asthma-like symptoms post COVID-19 hospitalization in children.

    Esmaeilzadeh, Hossein / Sanaei Dashti, Anahita / Mortazavi, Negar / Fatemian, Hossein / Vali, Mohebat

    BMC infectious diseases

    2022  Volume 22, Issue 1, Page(s) 244

    Abstract: ... 42) (58.5%) were not affected by asthma-like symptoms. 60.9% of the COVID-19 patients were male ... were followed and visited for cough and asthma evaluation one, 2 and 6 months later. Patients ... of asthma (33.3%), and Allergic rhinitis (85.2%). Rates of signs and symptoms during hospitalization were ...

    Abstract Backgrounds: Respiratory viruses are the main triggers of asthma. Coronavirus is shown to contribute to respiratory tract infections that can lead to prolonged cough and asthma.
    Objectives: Present study aimed to determine the risk of developing Persistent cough and asthma-like symptoms in hospitalized children due to COVID-19.
    Methods: This prospective study was carried out in a tertiary referral center. During the COVID-19 pandemic, 69 hospitalized pediatric patients admitted with COVID-19 were observed from February 2020 to January 2021. Clinical and laboratory data were recorded, and after discharge, patients were followed and visited for cough and asthma evaluation one, 2 and 6 months later. Patients with asthma-like diagnoses in follow up defined as asthma-like groups, and patients without any sign of asthma were categorized as the non-asthma group. Asthma-like co-morbids and risk factors were evaluated and compared between the two groups.
    Results: In follow-up, most of the COVID-19 hospitalized patients (N = 42) (58.5%) were not affected by asthma-like symptoms. 60.9% of the COVID-19 patients were male. The asthma-like group cases had a significantly familial history of asthma (63.0%), past medical history of asthma (33.3%), and Allergic rhinitis (85.2%). Rates of signs and symptoms during hospitalization were significantly higher in patients with COVID-19 and past medical history of asthma.
    Conclusions: We found an asthma-like prevalence of 41.5% in the cohort of COVID-19 hospitalized children. Family history of asthma and previous history of asthma and allergic rhinitis are risk factors for asthma-like after COVID-19 hospitalization. COVID-19 presentations are more severe in the asthma-like group.
    MeSH term(s) Asthma/complications ; Asthma/diagnosis ; Asthma/epidemiology ; COVID-19/epidemiology ; Child ; Cough/epidemiology ; Cough/etiology ; Hospitalization ; Humans ; Male ; Pandemics ; Prospective Studies ; SARS-CoV-2
    Language English
    Publishing date 2022-03-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041550-3
    ISSN 1471-2334 ; 1471-2334
    ISSN (online) 1471-2334
    ISSN 1471-2334
    DOI 10.1186/s12879-022-07252-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Predictors of post-COVID symptoms in Egyptian patients: Drugs used in COVID-19 treatment are incriminated.

    Abdelhafiz, Ahmed Samir / Ali, Asmaa / Maaly, Ayman Mohamed / Mahgoub, Mohamed Anwar / Ziady, Hany Hassan / Sultan, Eman Anwar

    PloS one

    2022  Volume 17, Issue 3, Page(s) e0266175

    Abstract: ... The goal of this study is evaluating the prevalence of post-COVID-19 symptoms among Egyptian patients and ... psychological symptoms for weeks or even months after infection, which is described as post-COVID syndrome ... Objectives: COVID-19 is a multisystem disease, and some patients suffer from physical or ...

    Abstract Objectives: COVID-19 is a multisystem disease, and some patients suffer from physical or psychological symptoms for weeks or even months after infection, which is described as post-COVID syndrome. The goal of this study is evaluating the prevalence of post-COVID-19 symptoms among Egyptian patients and detecting the factors associated with the presence of these symptoms.
    Methods: An on-line cross-sectional survey using Google Forms was used to conduct the present study, which took place between June and August 2021.
    Results: Three hundred and ninety-six participants filled in the survey. The mean age of participants was 41.4 years. Most participants had mild to moderate COVID-19 (81.31%). The prevalence of post-COVID-19 symptoms was 87.63%, where the most frequent symptom was fatigue (60.86%). Female sex, the presence of comorbidities, lower degree of education, longer disease duration, as well as severe and critical forms of the disease were significantly associated with the presence of post-COVID symptoms. Using regression analysis, the predictors of post-COVID symptoms were severe and critical forms of the disease and intake of antibiotics and corticosteroids for treatment of COVID-19.
    Conclusions: COVID-19 is followed by high prevalence of post-COVID symptoms. To the best of our knowledge, this is the first study to report the relationship between the use of antibiotics and the development of post-COVID symptoms. We recommend further studies to understand this relationship. We also recommend restricting the use of these drugs to indicated cases according to the international guidelines. More studies are needed to gain better understanding of post-COVID symptoms especially in females.
    MeSH term(s) Adult ; Anti-Bacterial Agents ; COVID-19/drug therapy ; COVID-19/epidemiology ; Cross-Sectional Studies ; Egypt/epidemiology ; Female ; Humans ; SARS-CoV-2
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2022-03-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0266175
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Evaluation of Short-Term Symptoms Associated With COVID-19 Vaccines Used Among Adolescents in Saudi Arabia.

    Alrowdhan, Fares K / Alwably, Abdulnasser / Altala, Abdulaziz S / Alfaraj, Hassan / Farawaty, Mhd Noor / Shaheen, Rakan S / Alenazi, Suliman A / Yousef, Einas M

    Cureus

    2022  Volume 14, Issue 9, Page(s) e29306

    Abstract: ... individuals who had a history of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, and ... side effects of COVID-19 vaccines. However, patient-reported data on COVID-19 vaccine-associated adverse ... Importantly, asthmatic participants have a higher incidence of COVID-19 vaccine side effects when compared ...

    Abstract Objectives: Several government-sponsored reporting systems have stated mild to moderate side effects of COVID-19 vaccines. However, patient-reported data on COVID-19 vaccine-associated adverse effects in adolescents are lacking. Our objective was to assess the short-term side effects of Pfizer-BioNTech BNT162b2 or Moderna mRNA-1273 vaccinations among teenagers in Saudi Arabia.
    Methods: A retrospective, cross-sectional study was conducted among individuals aged 12-18 years old who received one of the two mentioned vaccines between July 2021 and March 2022 in Riyadh, Saudi Arabia.
    Results: The most common short-term side effects reported for COVID-19 vaccines among teenagers in our study were fatigue, pain at the site of injection, fever, chills, headache, nausea, and vomiting. Female participants, individuals who had a history of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, and those who received two doses of the vaccine are at higher risk to develop side effects after getting the vaccine. Importantly, asthmatic participants have a higher incidence of COVID-19 vaccine side effects when compared to those with no history of chronic diseases.
    Conclusion: Our findings might enhance public trust in the COVID-19 vaccine, which could speed up the immunization procedure.
    Language English
    Publishing date 2022-09-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.29306
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Similar prevalence of long-term post-COVID symptoms in patients with asthma: A case-control study.

    Fernández-de-Las-Peñas, César / Torres-Macho, Juan / Velasco-Arribas, Maria / Arias-Navalón, Jose A / Guijarro, Carlos / Hernández-Barrera, Valentín / Canto-Diez, MGabriela

    The Journal of infection

    2021  Volume 83, Issue 2, Page(s) 237–279

    MeSH term(s) Asthma/complications ; Asthma/epidemiology ; COVID-19 ; Case-Control Studies ; Humans ; Prevalence ; SARS-CoV-2
    Language English
    Publishing date 2021-05-03
    Publishing country England
    Document type Letter
    ZDB-ID 424417-5
    ISSN 1532-2742 ; 0163-4453
    ISSN (online) 1532-2742
    ISSN 0163-4453
    DOI 10.1016/j.jinf.2021.04.034
    Database MEDical Literature Analysis and Retrieval System OnLINE

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