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Article: COVID-19 Virus Infection in Three Patients With Hypogammaglobulinemia.

Gesiotto, Quinto / Cheema, Asima / Avaiya, Kishan / Shah, Bijal / Greene, John

Cureus

2021  Volume 13, Issue 5, Page(s) e15256

Abstract: ... itself and chemotherapy. We present three cases of cancer patients with hypogammaglobulinemia with varying ... strategies available for immunocompromised patients. COVID-19 is a novel beta coronavirus known ... as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients with cancer are more susceptible to infection ...

Abstract The world is experiencing the COVID-19 outbreak and there are no evidence-based treatment strategies available for immunocompromised patients. COVID-19 is a novel beta coronavirus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients with cancer are more susceptible to infection than individuals without cancer due to their impaired humoral and cellular immune function caused by the malignancy itself and chemotherapy. We present three cases of cancer patients with hypogammaglobulinemia with varying clinical outcomes associated with infection. These include one mantle cell lymphoma patient with recurrent respiratory infection requiring intravenous immunoglobulin (IVIG) support and two multiple myeloma patients with continued viral shedding.
Language English
Publishing date 2021-05-26
Publishing country United States
Document type Case Reports
ZDB-ID 2747273-5
ISSN 2168-8184
ISSN 2168-8184
DOI 10.7759/cureus.15256
Database MEDical Literature Analysis and Retrieval System OnLINE

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