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  1. Article ; Online: Uterine artery embolization for leiomyomas: pre- and postprocedural evaluation with US.

    Ghai, Sangeet / Rajan, Dheeraj K / Benjamin, Matthew S / Asch, Murray R / Ghai, Sandeep

    Radiographics : a review publication of the Radiological Society of North America, Inc

    2005  Volume 25, Issue 5, Page(s) 1159–72; discussion 1173–6

    Abstract: ... pelvis prior to and following uterine artery embolization (UAE) for symptomatic leiomyomas (fibroids ... for both pre- and postprocedural evaluation of patients who undergo UAE. A proper understanding ... Transabdominal and transvaginal ultrasonography (US) are commonly used to assess the uterus and ...

    Abstract Transabdominal and transvaginal ultrasonography (US) are commonly used to assess the uterus and pelvis prior to and following uterine artery embolization (UAE) for symptomatic leiomyomas (fibroids). Preprocedural US may help identify relative contraindications for UAE, whereas postprocedural US can help determine the quality and quantity of fibroid involution and help identify any complications associated with the procedure. The consulting radiologist should be familiar with certain typical postprocedural US findings, which might otherwise be improperly interpreted, leading to unnecessary intervention. Magnetic resonance (MR) imaging or computed tomography will frequently provide the most accurate information in UAE patients with certain pathologic conditions, and early study results suggest that MR imaging may be helpful in predicting treatment response. Nevertheless, US is a readily available first-line imaging modality and a well-accepted method for both pre- and postprocedural evaluation of patients who undergo UAE. A proper understanding of the US findings in this patient population allows objective determination of treatment response and detection of most of the commonly recognized complications that are associated with UAE.
    MeSH term(s) Adult ; Embolization, Therapeutic ; Female ; Humans ; Leiomyoma/blood supply ; Leiomyoma/diagnostic imaging ; Leiomyoma/therapy ; Middle Aged ; Ultrasonography ; Uterine Neoplasms/blood supply ; Uterine Neoplasms/diagnostic imaging ; Uterine Neoplasms/therapy ; Uterus/blood supply
    Language English
    Publishing date 2005-09
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 603172-9
    ISSN 1527-1323 ; 0271-5333
    ISSN (online) 1527-1323
    ISSN 0271-5333
    DOI 10.1148/rg.255045019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Provision of a mobile uterine artery embolization service to medically underserved areas in Brazil.

    Kisilevzky, Nestor / Elkis, Henrique

    Journal of vascular and interventional radiology : JVIR

    2011  Volume 22, Issue 4, Page(s) 490–496

    Abstract: ... Materials and methods: One hundred women with symptomatic uterine leiomyomas were treated with UAE. A small ... period. Four public hospitals were visited in rotation. Pre- and postprocedural magnetic resonance (MR ... uterine artery embolization (UAE) program for patients in medically underserved, socioeconomically deprived areas ...

    Abstract Purpose: To determine the feasibility, efficacy, and safety of a mobile uterine artery embolization (UAE) program for patients in medically underserved, socioeconomically deprived areas.
    Materials and methods: One hundred women with symptomatic uterine leiomyomas were treated with UAE. A small truck containing a mobile c-arm and all needed supplies visited one hospital per week during a 6-month period. Four public hospitals were visited in rotation. Pre- and postprocedural magnetic resonance (MR) imaging and validated quality of life (QOL) questionnaires were obtained, and procedural details and complications were recorded.
    Results: Technical success was achieved in 97 of 100 women. Mean procedure time was 41 minutes (range, 15-140 min) and mean fluoroscopy time was 17 minutes (range, 6-45 min). Mean hospital stay was 1.03 days (range, 1-3 d) and mean time to resumption of normal activities was 8.2 days (range, 2-20 d). At 12 weeks, 88% of patients noted symptomatic improvement and 98% stated they would recommend the procedure to other women. Complete tumor ischemia was seen on postprocedural MR imaging in 92% of women, with a mean uterine volume reduction of 36.3% (range, -4.3% to 65%) and a mean tumor volume reduction of 57.1% (range, -23.4% to 95.8%). Health-related QOL scores increased from 41.4 points before UAE to 81.2 points at 12 weeks and 85.3 points at 1 year after UAE. Complications were recorded in seven women (7%): three puncture site hematomas, three readmissions for pain control, and one case of leiomyoma passage.
    Conclusions: A mobile interventional radiology unit is a feasible, efficient, and safe method to provide UAE to an underserved patient community. Outcomes and complications are similar to published results from centers with conventional angiographic facilities.
    MeSH term(s) Adult ; Brazil ; Feasibility Studies ; Female ; Health Services Accessibility ; Hospitals, Public ; Humans ; Leiomyoma/diagnosis ; Leiomyoma/therapy ; Length of Stay ; Longitudinal Studies ; Magnetic Resonance Imaging ; Medically Underserved Area ; Middle Aged ; Mobile Health Units ; Outcome and Process Assessment (Health Care) ; Program Evaluation ; Prospective Studies ; Quality of Life ; Radiography, Interventional ; Surveys and Questionnaires ; Time Factors ; Treatment Outcome ; Tumor Burden ; Uterine Artery Embolization/adverse effects ; Uterine Neoplasms/diagnosis ; Uterine Neoplasms/therapy
    Language English
    Publishing date 2011-04
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1137756-2
    ISSN 1535-7732 ; 1051-0443
    ISSN (online) 1535-7732
    ISSN 1051-0443
    DOI 10.1016/j.jvir.2010.12.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Clinical failure after uterine artery embolization: evaluation of patient and MR imaging characteristics.

    Toor, Sundeep S / Tan, Kongteng T / Simons, Martin E / Rajan, Dheeraj K / Beecroft, J Robert / Hayeems, Eran / Sniderman, Kenneth W

    Journal of vascular and interventional radiology : JVIR

    2008  Volume 19, Issue 5, Page(s) 662–667

    Abstract: ... with clinical failure after uterine artery embolization (UAE).: Materials and methods: Seventy-eight ... evaluation of fibroid symptoms and the need for further treatment after UAE. Findings at pre- and ... postprocedural MR imaging were compared, and data collected included changes in uterine and fibroid volumes ...

    Abstract Purpose: To investigate the patient and magnetic resonance (MR) imaging characteristics associated with clinical failure after uterine artery embolization (UAE).
    Materials and methods: Seventy-eight consecutive patients who underwent UAE were examined. Contrast-enhanced MR imaging was performed before and 4 months after the procedure, and clinical follow-up was performed at 15 months. Patients were divided into success and failure groups strictly on the basis of their clinical outcomes. Clinical follow-up included evaluation of fibroid symptoms and the need for further treatment after UAE. Findings at pre- and postprocedural MR imaging were compared, and data collected included changes in uterine and fibroid volumes, fibroid location, and fibroid perfusion.
    Results: Fifty-eight patients were placed into the success group and 20 into the failure group. There were no differences between the baseline characteristics of the two groups. The reduction in uterine and dominant fibroid volumes was greater in the success group compared with the failure group; however, the difference was not statistically significant (success group: [295/845] 34.9% vs [80/282.5] 28.3%, respectively, P=.18; failure group: [317/733] 43.2% vs [114/337.6] 33.9%, P=.32). The reduction in total fibroid volume was greater in the success group than the failure group ([189.6/393.5] 48.2% vs [148.7/439.9] 33.8%, respectively; P=.02) despite the fact that the percentage of fibroids completely infarcted was similar between the two groups ([136/172] 79% vs [41/50] 82%, P=.77). Pedunculated subserosal fibroids were more common in the failure group than in the success group (P<.03) and did not reduce in volume as significantly (53.8% vs 14.7%, respectively; P=.02).
    Conclusions: In general, the reduction in total fibroid volume after embolization is smaller in patients with poor clinical improvement. In addition, these patients have a higher number of pedunculated subserosal fibroids, and these fibroids tend to reduce in volume to a lesser extent.
    MeSH term(s) Adult ; Arteries ; Chi-Square Distribution ; Contrast Media ; Embolization, Therapeutic/methods ; Female ; Humans ; Leiomyoma/pathology ; Leiomyoma/therapy ; Magnetic Resonance Imaging ; Retrospective Studies ; Treatment Failure ; Uterine Neoplasms/pathology ; Uterine Neoplasms/therapy ; Uterus/blood supply
    Chemical Substances Contrast Media
    Language English
    Publishing date 2008-05
    Publishing country United States
    Document type Evaluation Studies ; Journal Article
    ZDB-ID 1137756-2
    ISSN 1535-7732 ; 1051-0443
    ISSN (online) 1535-7732
    ISSN 1051-0443
    DOI 10.1016/j.jvir.2007.12.454
    Database MEDical Literature Analysis and Retrieval System OnLINE

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