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Article ; Online: Evaluation of epidemiology, clinical features, prognosis, diagnosis and treatment outcomes of patients with COVID-19 in West Azerbaijan Province.

Gharebaghi, Naser / Farshid, Saman / Boroofeh, Behdad / Nejadrahim, Rahim / Mousavi, Jalil / Dindarian, Sina / Mohammadi, Sedra

International journal of clinical practice

2021  Volume 75, Issue 6, Page(s) e14108

Abstract: ... clinical and demographic characteristics of patients with COVID-19 were studied in Taleghani Hospital ... patients with COVID-19 during March and April 2020. Approved COVID-19 case was considered as a person ... of breath and cough were found in 62.8% and 49.3% of patients. Diabetes mellitus and hypertension were ...

Abstract Background: COVID-19 is considered a widespread concern in global public health. Diagnoses of COVID-19 in some cases are necessary because of severe prognosis. In this study, epidemiologies, clinical and demographic characteristics of patients with COVID-19 were studied in Taleghani Hospital, Urmia, Iran.
Methods: This descriptive-analytical cross-sectional study was carried out on 215 patients with COVID-19 during March and April 2020. Approved COVID-19 case was considered as a person with a positive respiratory sample performed by at least one of two RT-PCR methods or genetic sequencing. ANOVA repeated measure, independent t-test and logistic regression were done. A P < .05 was considered significant.
Results: The mean age of patients was 50.93 ± 17.92 years. Regarding gender, there were 91 females (42.3%) and 124 males (57.7%). The mean hospital stay, the temperature at admission, and onset of symptoms were 4.91 ± 3.68 days, 37.40 ± 0.96°C and 5.88 ± 4.80 days, respectively. Close contact with suspected people was found in 10.2% of patients. Additionally, 44 patients (20.5%) were smokers. Shortness of breath and cough were found in 62.8% and 49.3% of patients. Diabetes mellitus and hypertension were the most common comorbidities of patients. Regarding lung involvement, 33 patients (33%) were normal, most of the patients (n = 71) had 5%-25% involvement in their lung and a minority of patients (n = 13) had a severe condition of 50%-75% lung involvement. The association between smoking and mortality was tested using chi-square showing no significant difference (X
Conclusion: COVID-19 involves different organs of the body with different severity. In the meantime, smoking was not a risk factor for the virus or associated with severe manifestations of the disease. Patients with high creatinine and CPK, pulmonary involvement above 25%, and hypoxemia had a higher mortality rate. Increase of Spo2 by 1% can improve the patients by 24%. The results indicated that Kaletra had the most highest effect on improvement following COVID-19.
MeSH term(s) Adult ; Aged ; Azerbaijan ; COVID-19 ; Cross-Sectional Studies ; Female ; Humans ; Iran ; Male ; Middle Aged ; Prognosis ; SARS-CoV-2 ; Treatment Outcome
Language English
Publishing date 2021-03-22
Publishing country India
Document type Journal Article
ZDB-ID 1386246-7
ISSN 1742-1241 ; 1368-5031
ISSN (online) 1742-1241
ISSN 1368-5031
DOI 10.1111/ijcp.14108
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