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  1. Article ; Online: Electroceutical fabric lowers zeta potential and eradicates coronavirus infectivity upon contact.

    Ghatak, Subhadip / Khona, Dolly K / Sen, Abhishek / Huang, Kaixiang / Jagdale, Gargi / Singh, Kanhaiya / Gopalakrishnan, Vinoj / Cornetta, Kenneth G / Roy, Sashwati / Khanna, Savita / Baker, Lane A / Sen, Chandan K

    Scientific reports

    2021  Volume 11, Issue 1, Page(s) 21723

    Abstract: ... of 0.5 V, disrupts the infectivity of coronavirus upon contact by destabilizing the electrokinetic ... Coronavirus with intact infectivity attached to PPE surfaces pose significant threat to the spread ... of COVID-19. We tested the hypothesis that an electroceutical fabric, generating weak potential difference ...

    Abstract Coronavirus with intact infectivity attached to PPE surfaces pose significant threat to the spread of COVID-19. We tested the hypothesis that an electroceutical fabric, generating weak potential difference of 0.5 V, disrupts the infectivity of coronavirus upon contact by destabilizing the electrokinetic properties of the virion. Porcine respiratory coronavirus AR310 particles (10
    MeSH term(s) Animals ; Anti-Infective Agents ; Body Fluids ; COVID-19/prevention & control ; COVID-19/transmission ; Cell Line ; Cell Survival ; Electrochemistry/methods ; Fluoresceins ; Humans ; Hydrogen Peroxide ; Kinetics ; Nanoparticles ; Propidium ; SARS-CoV-2 ; Swine ; Temperature ; Tetrazolium Salts ; Textiles ; Thiazoles ; Virion ; Wound Healing
    Chemical Substances Anti-Infective Agents ; Fluoresceins ; Tetrazolium Salts ; Thiazoles ; calcein AM (148504-34-1) ; Propidium (36015-30-2) ; Hydrogen Peroxide (BBX060AN9V) ; thiazolyl blue (EUY85H477I)
    Language English
    Publishing date 2021-11-05
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-021-00910-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Electroceutical fabric lowers zeta potential and eradicates coronavirus infectivity upon contact

    Subhadip Ghatak / Dolly K. Khona / Abhishek Sen / Kaixiang Huang / Gargi Jagdale / Kanhaiya Singh / Vinoj Gopalakrishnan / Kenneth G. Cornetta / Sashwati Roy / Savita Khanna / Lane A. Baker / Chandan K. Sen

    Scientific Reports, Vol 11, Iss 1, Pp 1-

    2021  Volume 11

    Abstract: ... with the fabric for 1 or 5 min. Following one minute of contact, zeta potential of the porcine coronavirus was ... difference of 0.5 V, disrupts the infectivity of coronavirus upon contact by destabilizing the electrokinetic ... Abstract Coronavirus with intact infectivity attached to PPE surfaces pose significant threat ...

    Abstract Abstract Coronavirus with intact infectivity attached to PPE surfaces pose significant threat to the spread of COVID-19. We tested the hypothesis that an electroceutical fabric, generating weak potential difference of 0.5 V, disrupts the infectivity of coronavirus upon contact by destabilizing the electrokinetic properties of the virion. Porcine respiratory coronavirus AR310 particles (105) were placed in direct contact with the fabric for 1 or 5 min. Following one minute of contact, zeta potential of the porcine coronavirus was significantly lowered indicating destabilization of its electrokinetic properties. Size-distribution plot showed appearance of aggregation of the virus. Testing of the cytopathic effects of the virus showed eradication of infectivity as quantitatively assessed by PI-calcein and MTT cell viability tests. This work provides the rationale to consider the studied electroceutical fabric, or other materials with comparable property, as material of choice for the development of PPE in the fight against COVID-19.
    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2021-11-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  3. Book ; Online: Electroceutical Fabric Lowers Zeta Potential and Eradicates Coronavirus Infectivity upon Contact

    Sen, Abhishek / Khona, Dolly / Ghatak, Subhadip / Gopalakrishnan, Vinoj / Cornetta, Kenneth / Roy, Sashwati / Khanna, Savita / Sen, Chandan

    Other

    2020  

    Abstract: ... minute of contact, zeta potential of the coronavirus was significantly lowered indicating destabilization ... of 0.5V, disrupts the infectivity of coronavirus upon contact by destabilizing the electrokinetic ... Coronavirus with intact infectivity attached to PPE surfaces pose significant threat to the spread ...

    Abstract Coronavirus with intact infectivity attached to PPE surfaces pose significant threat to the spread of COVID-19. We tested the hypothesis that an electroceutical fabric, generating weak potential difference of 0.5V, disrupts the infectivity of coronavirus upon contact by destabilizing the electrokinetic properties of the virion. Respiratory coronavirus particles (105) were placed in direct contact with the fabric for 1 or 5 minutes. Viral particles (2.5-4x104) were recovered from the fabric. Following one minute of contact, zeta potential of the coronavirus was significantly lowered indicating destabilization of its electrokinetic properties. Size-distribution plot showed appearance of aggregation of the virus. Testing of the cytopathic effects of the virus showed eradication of infectivity as quantitatively assessed by PI-calcein and MTT cell viability tests. This work provides the rationale to consider the studied electroceutical fabric, or other materials with comparable property, as material of choice for the development of PPE in the fight against COVID-19.
    Keywords COVID-19 ; Personal Protective Equipment ; Electroceutical Fabric ; Nanoparticle ; covid19
    Language English
    Publishing date 2020-05-15
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Book ; Online: Electroceutical Fabric Lowers Zeta Potential and Eradicates Coronavirus Infectivity upon Contact

    Abhishek Sen / Dolly Khona / Subhadip Ghatak / Vinoj Gopalakrishnan / Kenneth Cornetta / Sashwati Roy / Savita Khanna / Chandan Sen

    2020  

    Abstract: ... minute of contact, zeta potential of the coronavirus was significantly lowered indicating destabilization ... of 0.5V, disrupts the infectivity of coronavirus upon contact by destabilizing the electrokinetic ... Coronavirus with intact infectivity attached to PPE surfaces pose significant threat to the spread ...

    Abstract Coronavirus with intact infectivity attached to PPE surfaces pose significant threat to the spread of COVID-19. We tested the hypothesis that an electroceutical fabric, generating weak potential difference of 0.5V, disrupts the infectivity of coronavirus upon contact by destabilizing the electrokinetic properties of the virion. Respiratory coronavirus particles (10 5 ) were placed in direct contact with the fabric for 1 or 5 minutes. Viral particles (2.5-4x10 4 ) were recovered from the fabric. Following one minute of contact, zeta potential of the coronavirus was significantly lowered indicating destabilization of its electrokinetic properties. Size-distribution plot showed appearance of aggregation of the virus. Testing of the cytopathic effects of the virus showed eradication of infectivity as quantitatively assessed by PI-calcein and MTT cell viability tests. This work provides the rationale to consider the studied electroceutical fabric, or other materials with comparable property, as material of choice for the development of PPE in the fight against COVID-19.
    Keywords Microbiology ; personal protective equipment ; COVID-19 ; nanoparticle ; covid19
    Publishing date 2020-05-15T09:56:56Z
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Book ; Online: Electroceutical Fabric Lowers Zeta Potential and Eradicates Coronavirus Infectivity upon Contact

    Sen, Abhishek / Khona, Dolly / Ghatak, Subhadip / Gopalakrishnan, Vinoj / Cornetta, Kenneth / Roy, Sashwati / Khanna, Savita / Sen, Chandan

    2020  

    Abstract: ... Following one minute of contact, zeta potential of the coronavirus was significantly lowered indicating ... of 0.5V, disrupts the infectivity of coronavirus upon contact by destabilizing the electrokinetic ... Coronavirus with intact infectivity attached to PPE surfaces pose significant threat to the spread ...

    Abstract Coronavirus with intact infectivity attached to PPE surfaces pose significant threat to the spread of COVID-19. We tested the hypothesis that an electroceutical fabric, generating weak potential difference of 0.5V, disrupts the infectivity of coronavirus upon contact by destabilizing the electrokinetic properties of the virion. Respiratory coronavirus particles (10<sup>5</sup>) were placed in direct contact with the fabric for 1 or 5 minutes. Viral particles (2.5-4x10<sup>4</sup>) were recovered from the fabric. Following one minute of contact, zeta potential of the coronavirus was significantly lowered indicating destabilization of its electrokinetic properties. Size-distribution plot showed appearance of aggregation of the virus. Testing of the cytopathic effects of the virus showed eradication of infectivity as quantitatively assessed by PI-calcein and MTT cell viability tests. This work provides the rationale to consider the studied electroceutical fabric, or other materials with comparable property, as material of choice for the development of PPE in the fight against COVID-19.
    Keywords covid19
    Publisher American Chemical Society (ACS)
    Publishing country us
    Document type Book ; Online
    DOI 10.26434/chemrxiv.12307214
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Book ; Online: Electroceutical Fabric Lowers Zeta Potential and Eradicates Coronavirus Infectivity upon Contact

    Sen, Abhishek / Khona, Dolly / Ghatak, Subhadip / Gopalakrishnan, Vinoj / Cornetta, Kenneth / Roy, Sashwati / Khanna, Savita / Sen, Chandan

    2020  

    Abstract: ... Following one minute of contact, zeta potential of the coronavirus was significantly lowered indicating ... of 0.5V, disrupts the infectivity of coronavirus upon contact by destabilizing the electrokinetic ... Coronavirus with intact infectivity attached to PPE surfaces pose significant threat to the spread ...

    Abstract Coronavirus with intact infectivity attached to PPE surfaces pose significant threat to the spread of COVID-19. We tested the hypothesis that an electroceutical fabric, generating weak potential difference of 0.5V, disrupts the infectivity of coronavirus upon contact by destabilizing the electrokinetic properties of the virion. Respiratory coronavirus particles (10<sup>5</sup>) were placed in direct contact with the fabric for 1 or 5 minutes. Viral particles (2.5-4x10<sup>4</sup>) were recovered from the fabric. Following one minute of contact, zeta potential of the coronavirus was significantly lowered indicating destabilization of its electrokinetic properties. Size-distribution plot showed appearance of aggregation of the virus. Testing of the cytopathic effects of the virus showed eradication of infectivity as quantitatively assessed by PI-calcein and MTT cell viability tests. This work provides the rationale to consider the studied electroceutical fabric, or other materials with comparable property, as material of choice for the development of PPE in the fight against COVID-19.
    Keywords covid19
    Publisher American Chemical Society (ACS)
    Publishing country us
    Document type Book ; Online
    DOI 10.26434/chemrxiv.12307214.v1
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

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