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Article ; Online: Sudden neck swelling with rash as late manifestation of COVID-19: a case report.

Giannitto, Caterina / Bonifacio, Cristiana / Esposito, Susanna / Ammirabile, Angela / Mercante, Giuseppe / De Virgilio, Armando / Spriano, Giuseppe / Heffler, Enrico / Lofino, Ludovica / Politi, Letterio Salvatore / Balzarini, Luca

BMC infectious diseases

2021  Volume 21, Issue 1, Page(s) 232

Abstract: ... in literature.: Case presentation: We report a case of a sudden neck swelling and rash likely due to late ... of CoronaVirus Disease 19 (COVID-19), there have been no documented cases of sudden neck swelling with rash ... clinical condition and with a negative swab.: Conclusion: Sudden neck swelling with rash may be ...

Abstract Background: Although there are reports of otolaryngological symptoms and manifestations of CoronaVirus Disease 19 (COVID-19), there have been no documented cases of sudden neck swelling with rash in patients with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection described in literature.
Case presentation: We report a case of a sudden neck swelling and rash likely due to late SARS-CoV-2 in a 64-year-old woman. The patient reported COVID-19 symptoms over the previous three weeks. Computed Tomography (CT) revealed a diffuse soft-tissue swelling and edema of subcutaneous tissue, hypodermis, and muscular and deep fascial planes. All the differential diagnoses were ruled out. Both the anamnestic history of the patient's husband who had died of COVID-19 with and the collateral findings of pneumonia and esophageal wall edema suggested the association with COVID-19. This was confirmed by nasopharyngeal swab polymerase chain reaction. The patient was treated with lopinavir/ritonavir, hydroxychloroquine and piperacillin/tazobactam for 7 days. The neck swelling resolved in less than 24 h, while the erythema was still present up to two days later. The patient was discharged after seven days in good clinical condition and with a negative swab.
Conclusion: Sudden neck swelling with rash may be a coincidental presentation, but, in the pandemic context, it is most likely a direct or indirect complication of COVID-19.
MeSH term(s) COVID-19/complications ; COVID-19/diagnostic imaging ; Edema/etiology ; Exanthema/etiology ; Female ; Humans ; Middle Aged ; Neck/pathology ; SARS-CoV-2 ; Tomography, X-Ray Computed ; COVID-19 Drug Treatment
Language English
Publishing date 2021-02-27
Publishing country England
Document type Case Reports ; Journal Article
ZDB-ID 2041550-3
ISSN 1471-2334 ; 1471-2334
ISSN (online) 1471-2334
ISSN 1471-2334
DOI 10.1186/s12879-021-05911-4
Database MEDical Literature Analysis and Retrieval System OnLINE

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