Article ; Online: COVID-19 Encephalitis with SARS-CoV-2 Detected in Cerebrospinal Fluid Presenting as a Stroke Mimic.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
2021 Volume 30, Issue 9, Page(s) 105915
Abstract: We report the case of a 35-year-old male with COVID-19 encephalitis presenting as a stroke mimic ... detected in cerebrospinal fluid. Electroencephalography demonstrated excess in slow waves, but neuroimaging ... received thrombolysis for a suspected ischaemic stroke, but later became febrile and SARS-CoV-2 was ...
| Abstract | We report the case of a 35-year-old male with COVID-19 encephalitis presenting as a stroke mimic with sudden-onset expressive and receptive dysphasia, mild confusion and right arm incoordination. The patient received thrombolysis for a suspected ischaemic stroke, but later became febrile and SARS-CoV-2 was detected in cerebrospinal fluid. Electroencephalography demonstrated excess in slow waves, but neuroimaging was reported as normal. Respiratory symptoms were absent throughout and nasopharyngeal swab was negative for SARS-CoV-2. At the most recent follow-up, the patient had made a full neurological recovery. Clinicians should therefore consider testing for SARS-CoV-2 in CSF in patients who present with acute focal neurology, confusion and fever during the pandemic, even when there is no evidence of respiratory infection. |
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| MeSH term(s) | Adult ; COVID-19/cerebrospinal fluid ; COVID-19/diagnosis ; COVID-19/virology ; COVID-19 Nucleic Acid Testing ; Diagnosis, Differential ; Electroencephalography ; Encephalitis, Viral/cerebrospinal fluid ; Encephalitis, Viral/diagnosis ; Encephalitis, Viral/virology ; Humans ; Ischemic Stroke/diagnosis ; Magnetic Resonance Imaging ; Male ; Predictive Value of Tests ; RNA, Viral/cerebrospinal fluid ; SARS-CoV-2/genetics ; Tomography, X-Ray Computed | |||||
| Chemical Substances | RNA, Viral | |||||
| Language | English | |||||
| Publishing date | 2021-05-31 | |||||
| Publishing country | United States | |||||
| Document type | Case Reports | |||||
| ZDB-ID | 1131675-5 | |||||
| ISSN | 1532-8511 ; 1052-3057 | |||||
| ISSN (online) | 1532-8511 | |||||
| ISSN | 1052-3057 | |||||
| DOI | 10.1016/j.jstrokecerebrovasdis.2021.105915 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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