Article ; Online: Prognostic Value of Immune-Inflammatory Index in PSI IV-V Patients with COVID-19.
2021 Volume 2021, Page(s) 9987931
Abstract: ... the relationship between immune-inflammatory index and mortality in PSI IV-V patients with COVID-19.: Methods ... for mortality in PSI IV-V patients with COVID-19. Increased procalcitonin and neutrophil-to-lymphocyte ratio ... Objective: Respiratory failure is the leading cause of mortality in COVID-19 patients ...
| Abstract | Objective: Respiratory failure is the leading cause of mortality in COVID-19 patients, characterized by a generalized disbalance of inflammation. The aim of this study was to investigate the relationship between immune-inflammatory index and mortality in PSI IV-V patients with COVID-19. Methods: We retrospectively reviewed the medical records of COVID-19 patients from Feb. to Apr. 2020 in the Zhongfa Xincheng Branch of Tongji Hospital, Wuhan, China. Patients who presented high severity of COVID-19-related pneumonia were enrolled for further analysis according to the Pneumonia Severity Index (PSI) tool. Results: A total of 101 patients diagnosed with COVID-19 were identified at initial research. The survival analysis revealed that mortality of the PSI IV-V cohort was significantly higher than the PSI I-III group ( Conclusion: Procalcitonin and neutrophil-to-lymphocyte ratio may potentially be effective predictors for mortality in PSI IV-V patients with COVID-19. Increased procalcitonin and neutrophil-to-lymphocyte ratio were associated with greater risk of mortality. |
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| MeSH term(s) | Aged ; Aged, 80 and over ; Biomarkers/blood ; COVID-19/immunology ; COVID-19/mortality ; COVID-19/physiopathology ; China/epidemiology ; Cohort Studies ; Female ; Humans ; Inflammation/immunology ; Inflammation/physiopathology ; Lymphocytes/immunology ; Male ; Middle Aged ; Neutrophils/immunology ; Pandemics ; Pneumonia, Viral/immunology ; Pneumonia, Viral/mortality ; Pneumonia, Viral/physiopathology ; Procalcitonin/blood ; Prognosis ; Retrospective Studies ; Risk Factors ; SARS-CoV-2 ; Severity of Illness Index ; Survival Analysis |
| Chemical Substances | Biomarkers ; Procalcitonin |
| Language | English |
| Publishing date | 2021-08-16 |
| Publishing country | United States |
| Document type | Journal Article ; Observational Study |
| ZDB-ID | 2698540-8 |
| ISSN | 2314-6141 ; 2314-6133 |
| ISSN (online) | 2314-6141 |
| ISSN | 2314-6133 |
| DOI | 10.1155/2021/9987931 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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