Article ; Online: COVID-19 prevalence and outcomes in patients receiving biologic therapies at an infusion center in New York City.
Clinical immunology (Orlando, Fla.)
2021 Volume 230, Page(s) 108803
Abstract: ... infusion center in New York City during the height of the pandemic. 2074 patients received treatment ... To better understand COVID-19 infection in patients receiving biologic and ... immunomodulatory therapies, we evaluated prevalence and outcomes for symptomatic cases of COVID-19 at a large therapeutic ...
| Abstract | To better understand COVID-19 infection in patients receiving biologic and immunomodulatory therapies, we evaluated prevalence and outcomes for symptomatic cases of COVID-19 at a large therapeutic infusion center in New York City during the height of the pandemic. 2074 patients received treatment with biologic infusions at our center between March and May 2020, and 34 patients developed symptomatic COVID-19 infection, for an overall low rate of 1.64%. The majority of infections and deaths were in a small subset of patients with a primary immunodeficiency. Patients with inflammatory or autoimmune conditions requiring biologic therapies tended to have mild cases. Higher inflammatory responses were observed in patients who died. |
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| MeSH term(s) | Ambulatory Care Facilities ; Autoimmune Diseases/therapy ; Biological Factors/administration & dosage ; Biomarkers ; COVID-19/complications ; COVID-19/epidemiology ; COVID-19/mortality ; Comorbidity ; Female ; Humans ; Incidence ; Inflammation/metabolism ; Male ; Middle Aged ; New York City/epidemiology ; Prevalence ; SARS-CoV-2 | |||||
| Chemical Substances | Biological Factors ; Biomarkers | |||||
| Language | English | |||||
| Publishing date | 2021-07-21 | |||||
| Publishing country | United States | |||||
| Document type | Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't | |||||
| ZDB-ID | 1459903-x | |||||
| ISSN | 1521-7035 ; 1521-6616 | |||||
| ISSN (online) | 1521-7035 | |||||
| ISSN | 1521-6616 | |||||
| DOI | 10.1016/j.clim.2021.108803 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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