Article ; Online: Transmission dynamics of SARS-CoV-2 on the Diamond Princess uncovered using viral genome sequence analysis.
2021 Volume 779, Page(s) 145496
Abstract: ... coronavirus 2 (SARS-CoV-2) occurred aboard the Diamond Princess cruise ship between her January 20 departure ... substitution rate of 240 SARS-CoV-2 whole-genome sequences was approximately 7.13 × 10 ... of SARS-CoV-2 during the outbreak. Using a Bayesian coalescent-based method, the estimated mean nucleotide ...
| Abstract | An outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) occurred aboard the Diamond Princess cruise ship between her January 20 departure and late February 2020. Here, we used phylodynamic analyses to investigate the transmission dynamics of SARS-CoV-2 during the outbreak. Using a Bayesian coalescent-based method, the estimated mean nucleotide substitution rate of 240 SARS-CoV-2 whole-genome sequences was approximately 7.13 × 10 |
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| MeSH term(s) | Bayes Theorem ; COVID-19/transmission ; Disease Outbreaks/prevention & control ; Humans ; Phylogeny ; Polymorphism, Single Nucleotide ; Quarantine ; RNA, Viral/genetics ; SARS-CoV-2/classification ; SARS-CoV-2/genetics ; SARS-CoV-2/isolation & purification ; Sequence Analysis, RNA ; Ships ; Whole Genome Sequencing/methods |
| Chemical Substances | RNA, Viral |
| Language | English |
| Publishing date | 2021-02-13 |
| Publishing country | Netherlands |
| Document type | Journal Article |
| ZDB-ID | 391792-7 |
| ISSN | 1879-0038 ; 0378-1119 |
| ISSN (online) | 1879-0038 |
| ISSN | 0378-1119 |
| DOI | 10.1016/j.gene.2021.145496 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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