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Artikel ; Online: Fatal parvovirus B19 infections: a report of two autopsy cases.

Hu, Hsuan-Yun / Wei, Shyh-Yuh / Huang, Wei-Hsiang / Pan, Chih-Hsin

International journal of legal medicine

2018  Band 133, Heft 2, Seite(n) 553–560

Abstract: ... of PVB19 infection are unusual; nevertheless, the two cases reported here are rare examples of PVB19 ... molecular biology. The cases also highlight the importance of forensic autopsy in vaccine-related death. As vaccine ... Parvovirus B19 (PVB19) commonly infects children and is usually asymptomatic. Lethal outcomes ...

Abstract Parvovirus B19 (PVB19) commonly infects children and is usually asymptomatic. Lethal outcomes of PVB19 infection are unusual; nevertheless, the two cases reported here are rare examples of PVB19-induced hemophagocytic syndrome and myocarditis in infants and children. The two cases show the indisputable usefulness of immunohistochemistry and in situ hybridization in the detection of PVB19. In the death investigations, histopathological examinations provided stronger evidence than did serology or molecular biology. The cases also highlight the importance of forensic autopsy in vaccine-related death. As vaccine-related deaths are what people fear and may cause declines in vaccination rates, it is important to clarify deaths temporally or causally associated with vaccine administration.
Mesh-Begriff(e) Bone Marrow/pathology ; Bone Marrow/virology ; Child ; Disseminated Intravascular Coagulation/virology ; Erythema Infectiosum/diagnosis ; Fatal Outcome ; Female ; Humans ; Infant ; Influenza Vaccines ; Male ; Myocarditis/pathology ; Myocarditis/virology ; Parvovirus B19, Human/isolation & purification ; Phagocytosis
Chemische Substanzen Influenza Vaccines
Schlagwörter covid19
Sprache Englisch
Erscheinungsdatum 2018-09-01
Erscheinungsland Germany
Dokumenttyp Case Reports ; Journal Article
ZDB-ID 1055109-8
ISSN 1437-1596 ; 0937-9827
ISSN (online) 1437-1596
ISSN 0937-9827
DOI 10.1007/s00414-018-1921-6
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