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Article ; Online: COVID-19 and Adolescent Mental Health in the United Kingdom.

Hu, Yang / Qian, Yue

The Journal of adolescent health : official publication of the Society for Adolescent Medicine

2021 Volume 69, Issue 1, Page(s) 26–32

Abstract: Purpose: This study examines the mental health impact of the COVID-19 pandemic on adolescents ... in the United Kingdom as well as social, demographic, and economic variations in the impact.: Methods: Nationally ... The Strengths and Difficulties Questionnaire was used to measure adolescents' mental health.: Results ...

Abstract	Purpose: This study examines the mental health impact of the COVID-19 pandemic on adolescents in the United Kingdom as well as social, demographic, and economic variations in the impact. Methods: Nationally representative longitudinal panel data from the Understanding Society COVID-19 survey were analyzed. The analytical sample comprises 886 adolescents aged 10-16 years surveyed both before and during the pandemic. The Strengths and Difficulties Questionnaire was used to measure adolescents' mental health. Results: The results from person fixed-effects regression models show that adolescents with better-than-median mental health before the pandemic have experienced an increase in their emotional problems, conduct problems, hyperactivity, and peer relationship problems, but a decrease in their prosocial tendency during the pandemic. In contrast, adolescents with worse-than-median mental health before the pandemic have experienced opposite changes in each Strengths and Difficulties Questionnaire domain. Further results from lagged dependent variable regression models show that compared with girls, boys have experienced a smaller increase in emotional problems but a greater decrease in prosocial tendency. The negative mental health impact is particularly prominent among adolescents in one-parent, one-child, and low-income households. Adult household members' COVID-19 symptoms and illness have undermined adolescents' peer relationships. Conclusions: The results reveal the pandemic's diverse impacts on adolescent mental health, which vary with adolescents' prepandemic mental health and sociodemographic backgrounds. The findings underline the need for tailored mental health support for adolescents and targeted measures to mitigate inequalities in the mental health impact of the pandemic.
MeSH term(s)	Adolescent ; Adult ; COVID-19 ; Child ; Female ; Humans ; Male ; Mental Disorders/epidemiology ; Mental Health ; Pandemics ; SARS-CoV-2 ; United Kingdom/epidemiology
Language	English
Publishing date	2021-06-25
Publishing country	United States
Document type	Journal Article
ZDB-ID	1063374-1
ISSN	1879-1972 ; 1054-139X
ISSN (online)	1879-1972
ISSN	1054-139X
DOI	10.1016/j.jadohealth.2021.04.005
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Article ; Online: Mindfulness meditation use in Britain during the COVID-19 pandemic.

Simonsson, Otto / Fisher, Stephen D

PloS one

2024 Volume 19, Issue 5, Page(s) e0303349

Abstract: ... of mindfulness meditation use and also its perceived mental health effects during the COVID-19 pandemic ... and also its perceived mental health effects during the COVID-19 pandemic.: Results: The findings ... models, negative mental health effects from mindfulness practice during the COVID-19 pandemic were not ...

Abstract	Objectives: The objectives of this study were to examine the prevalence and associations of mindfulness meditation use and also its perceived mental health effects during the COVID-19 pandemic. Methods: Using repeated cross-sectional data from broad online samples weighted to be representative of the adult population in Britain, we estimated the prevalence of mindfulness meditation use and employed logistic regression models to investigate sociodemographic and political associations of mindfulness meditation use and also its perceived mental health effects during the COVID-19 pandemic. Results: The findings suggest that 16 percent of adults in Britain had learnt to practice mindfulness in 2021. In covariate-adjusted regression models, having learnt to practice mindfulness was more common among young and middle-aged adults, residents in London, and respondents who voted for the Liberal Democrats. Among mindfulness meditation users who reported having practiced mindfulness during the COVID-19 pandemic, 60 percent reported that it positively affected their mental health and 24 percent reported that it negatively affected their mental health. Notably, 41 percent of respondents with children under 18 (versus 13 percent of those without minors) reported negative mental health effects. In covariate-adjusted regression models, negative mental health effects from mindfulness practice during the COVID-19 pandemic were not concentrated in any particular groups, except for respondents with children under 18. Conclusions: Mindfulness meditation has become widespread in Britain, but the results in this study suggest that mindfulness meditation use may be concentrated in certain sociodemographic and political groups. The results also suggest that practicing mindfulness during the COVID-19 pandemic had positive mental health effects for a majority of users, but approximately one-quarter of users reported negative mental health effects. It is therefore important for future research to continue monitoring the prevalence of mindfulness meditation use in society and to investigate under what circumstances, for whom, and in what ways mindfulness-based practices may have negative effects on mental health.
MeSH term(s)	Humans ; COVID-19/epidemiology ; COVID-19/psychology ; COVID-19/prevention & control ; Mindfulness/methods ; Meditation/psychology ; United Kingdom/epidemiology ; Male ; Female ; Adult ; Middle Aged ; Cross-Sectional Studies ; Mental Health ; Young Adult ; Adolescent ; Pandemics ; Aged ; SARS-CoV-2
Language	English
Publishing date	2024-05-13
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0303349
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Article: The experiences and impact of the COVID-19 pandemic on young carers: practice implications and planning for future health emergencies.

Hayes, D / Fancourt, D / Burton, A

Child and adolescent psychiatry and mental health

2024 Volume 18, Issue 1, Page(s) 2

Abstract: ... on by the COVID-19 pandemic. We explored the impact of the pandemic and associated restrictions on mental health ... wellbeing and access to support in young carers in the United Kingdom (UK) to understand how to improve ... overarching themes pertaining to the impact of the pandemic and associated restrictions on mental health ...

Abstract	Background: Young carers are children or young people aged up to 25 years old who undertake unpaid caring responsibilities for a friend or family member. Young carers faced significant challenges brought on by the COVID-19 pandemic. We explored the impact of the pandemic and associated restrictions on mental health, wellbeing and access to support in young carers in the United Kingdom (UK) to understand how to improve services, as well as support this population in future health emergencies. Method: We conducted 22 qualitative semi-structured interviews from May to November 2021 with 14 young carers and eight staff working in organisations that supported them. Interviews took place remotely over video or telephone call and explored participant experiences of the pandemic and its impact on their health, wellbeing and caring responsibilities. We used reflexive thematic analysis to analyse interview transcripts. Results: We identified four overarching themes pertaining to the impact of the pandemic and associated restrictions on mental health, wellbeing and access to support in young carers in the UK: (1) challenges in protecting loved ones from the virus, (2) changes to and loss of routine, (3) reduced access to pre-pandemic informal and formal support structures and (4) better understanding of inner resilience and goals. Many participants struggled with their mental health and wellbeing as a result of pandemic related restrictions which impacted on support structures for themselves and the individual they cared for. However, positive impacts pertained to additional support provided by local authority and third sector organisations. Conclusions: Our findings highlight some of the changes that affected young carers during the COVID-19 pandemic. The impact of changes to routine and a reduction in pre-pandemic support were the greatest concerns reported by participants in this study. The additional support provided by local authority and third sector organisations during social restrictions suggests such organisations could play a greater role in supporting this population going forward and that schools and Governments may wish to put in additional strategies and provisions to protect young carers in the future.
Language	English
Publishing date	2024-01-03
Publishing country	England
Document type	Journal Article
ZDB-ID	2379599-2
ISSN	1753-2000
ISSN	1753-2000
DOI	10.1186/s13034-023-00697-6
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Article ; Online: Severe COVID anxiety among adults in the United Kingdom: cohort study and nested feasibility trial.

Crawford, Mike J / King, Jacob D / McQuaid, Aisling / Bassett, Paul / Leeson, Verity C / Tella, Oluwaseun / Di Simplicio, Martina / Tyrer, Peter / Tyrer, Helen / Watt, Richard G / Barnicot, Kirsten

BMC psychiatry

2024 Volume 24, Issue 1, Page(s) 27

Abstract: Background: People with severe COVID anxiety have poor mental health and impaired functioning ... of the trial received four or more sessions of CBT-HA. We found improved mental health and social ... Cognitive Behavioural Therapy for Health Anxiety (CBT-HA). Exclusion criteria were recent COVID-19, current self-isolation, or ...

Abstract	Background: People with severe COVID anxiety have poor mental health and impaired functioning, but the course of severe COVID anxiety is unknown and the quality of evidence on the acceptability and impact of psychological interventions is low. Methods: A quantitative cohort study with a nested feasibility trial. Potential participants aged 18 and over, living in the UK with severe COVID anxiety, were recruited online and from primary care services. We examined levels of COVID anxiety in the six months after recruitment, and factors that influenced this, using linear regression. Those scoring above 20 on the short Health Anxiety Inventory were invited to participate in a feasibility trial of remotely delivered Cognitive Behavioural Therapy for Health Anxiety (CBT-HA). Exclusion criteria were recent COVID-19, current self-isolation, or current receipt of psychological treatment. Key outcomes for the feasibility trial were the level of uptake of CBT-HA and the rate of follow-up. Results: 204 (70.2%) of 285 people who took part in the cohort study completed the six month follow-up, for whom levels of COVID anxiety fell from 12.4 at baseline to 6.8 at six months (difference = -5.5, 95% CI = -6.0 to -4.9). Reductions in COVID anxiety were lower among older people, those living with a vulnerable person, those with lower baseline COVID anxiety, and those with higher levels of generalised anxiety and health anxiety at baseline. 36 (90%) of 40 participants enrolled in the nested feasibility trial were followed up at six months. 17 (80.9%) of 21 people in the active arm of the trial received four or more sessions of CBT-HA. We found improved mental health and social functioning among those in the active, but not the control arm of the trial (Mean difference in total score on the Work and Social Adjustment Scale between baseline and follow up, was 9.7 (95% CI = 5.8-13.6) among those in the active, and 1.0 (95% C.I. = -4.6 to 6.6) among those in the control arm of the trial. Conclusions: While the mental health of people with severe COVID anxiety appears to improve over time, many continue to experience high levels of anxiety and poor social functioning. Health anxiety is highly prevalent among people with severe COVID anxiety and may provide a target for psychological treatment. Trial registration: Retrospectively registered at ISRCTN14973494 on 09/09/2021.
MeSH term(s)	Adolescent ; Adult ; Aged ; Humans ; Anxiety/therapy ; Cohort Studies ; COVID-19 ; Feasibility Studies ; United Kingdom/epidemiology
Language	English
Publishing date	2024-01-06
Publishing country	England
Document type	Clinical Trial ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2050438-X
ISSN	1471-244X ; 1471-244X
ISSN (online)	1471-244X
ISSN	1471-244X
DOI	10.1186/s12888-023-05446-9
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Article ; Online: Ambulance Services Attendance for Mental Health and Overdose Before and During COVID-19 in Canada and the United Kingdom: Interrupted Time Series Study.

Law, Graham / Cooper, Rhiannon / Pirrie, Melissa / Ferron, Richard / McLeod, Brent / Spaight, Robert / Siriwardena, A Niroshan / Agarwal, Gina

JMIR public health and surveillance

2024 Volume 10, Page(s) e46029

Abstract: ... for mental health and overdose in the United Kingdom (East Midlands region) and Canada (Hamilton and Niagara regions ... Background: The COVID-19 pandemic impacted mental health and health care systems worldwide ... United Kingdom: incidence rate ratio [IRR] 1.002, 95% CI 1.002-1.003 for mental health). However, substantial ...

Abstract	Background: The COVID-19 pandemic impacted mental health and health care systems worldwide. Objective: This study examined the COVID-19 pandemic's impact on ambulance attendances for mental health and overdose, comparing similar regions in the United Kingdom and Canada that implemented different public health measures. Methods: An interrupted time series study of ambulance attendances was conducted for mental health and overdose in the United Kingdom (East Midlands region) and Canada (Hamilton and Niagara regions). Data were obtained from 182,497 ambulance attendance records for the study period of December 29, 2019, to August 1, 2020. Negative binomial regressions modeled the count of attendances per week per 100,000 population in the weeks leading up to the lockdown, the week the lockdown was initiated, and the weeks following the lockdown. Stratified analyses were conducted by sex and age. Results: Ambulance attendances for mental health and overdose had very small week-over-week increases prior to lockdown (United Kingdom: incidence rate ratio [IRR] 1.002, 95% CI 1.002-1.003 for mental health). However, substantial changes were observed at the time of lockdown; while there was a statistically significant drop in the rate of overdose attendances in the study regions of both countries (United Kingdom: IRR 0.573, 95% CI 0.518-0.635 and Canada: IRR 0.743, 95% CI 0.602-0.917), the rate of mental health attendances increased in the UK region only (United Kingdom: IRR 1.125, 95% CI 1.031-1.227 and Canada: IRR 0.922, 95% CI 0.794-1.071). Different trends were observed based on sex and age categories within and between study regions. Conclusions: The observed changes in ambulance attendances for mental health and overdose at the time of lockdown differed between the UK and Canada study regions. These results may inform future pandemic planning and further research on the public health measures that may explain observed regional differences.
MeSH term(s)	Humans ; COVID-19/epidemiology ; Ambulances/statistics & numerical data ; United Kingdom/epidemiology ; Canada/epidemiology ; Interrupted Time Series Analysis ; Drug Overdose/epidemiology ; Male ; Adult ; Female ; Middle Aged ; Young Adult ; Adolescent ; Aged ; Mental Disorders/epidemiology
Language	English
Publishing date	2024-05-10
Publishing country	Canada
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	2369-2960
ISSN (online)	2369-2960
DOI	10.2196/46029
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Article ; Online: The Impact of COVID-19 on Mental Health Services in Scotland, UK.

Cooke, Elizabeth A / Lemanska, Agnieszka / Livings, Jennifer / Thomas, Spencer A

Studies in health technology and informatics

2022 Volume 295, Page(s) 59–62

Abstract: There is a global emergency in relation to mental health (MH) and healthcare. In the UK each year ... however, that child and adolescent services were comparatively less impacted by the pandemic than adult services ... COVID-19 has deepened the healthcare gap. We investigated the effect of COVID-19 on waiting times for MH ...

Abstract	There is a global emergency in relation to mental health (MH) and healthcare. In the UK each year, 1 in 4 people will experience MH problems. Healthcare services are increasingly oversubscribed, and COVID-19 has deepened the healthcare gap. We investigated the effect of COVID-19 on waiting times for MH services in Scotland. We used national registers of MH services provided by Public Health Scotland. The results show that waiting times for adults and children increased drastically during the pandemic. This was seen nationally and across most of the administrative regions of Scotland. We find, however, that child and adolescent services were comparatively less impacted by the pandemic than adult services. This is potentially due to prioritisation of paediatric patients, or due to an increasing demand on adult services triggered by the pandemic itself.
MeSH term(s)	Adolescent ; Adult ; COVID-19/epidemiology ; Child ; Humans ; Mental Health ; Mental Health Services ; Scotland/epidemiology ; United Kingdom/epidemiology
Language	English
Publishing date	2022-06-30
Publishing country	Netherlands
Document type	Journal Article
ISSN	1879-8365
ISSN (online)	1879-8365
DOI	10.3233/SHTI220660
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Article ; Online: Mental health inequalities, challenges and support needs during COVID-19: a qualitative study of 14-to-25-year-olds in London.

Lee, Jasmine / Wong, Keri Ka-Yee

BMJ open

2024 Volume 14, Issue 4, Page(s) e080161

Abstract: Objectives: The impact of the COVID-19 pandemic on adolescent's mental health and relationships ... mental health and life-skill workshops with young people, documents adolescents' lived experience and support ... needs 4 years on from the COVID-19 pandemic.: Design: 20 semi-structured interviews and 6 ...

Abstract	Objectives: The impact of the COVID-19 pandemic on adolescent's mental health and relationships has received growing attention, yet the challenges and support needs of adolescents living in existing deprivation are not well understood. The current qualitative study, part of a broader project cocreating mental health and life-skill workshops with young people, documents adolescents' lived experience and support needs 4 years on from the COVID-19 pandemic. Design: 20 semi-structured interviews and 6 focus groups were transcribed and thematically analysed in NVivo V.12 to inform codesigned workshops to support adolescents' needs. Setting: Islington borough in North London, United Kingdom. Participants: 20 adolescents aged 14-25 years (mean=18.3; 60% female, 60% white) from Islington with a history of difficulties (eg, mental health, deprivation, court order) were referred by Islington local authority teams to our study. Results: Thematic analyses revealed eight themes on adolescents' COVID-19 experiences and five associated suggestions on 'support needs': health challenges and support; relationships and support; routines and support; educational challenges and learning support; inequality and support; distrust; loss of opportunities and grief. Conclusions: In our qualitative study, adolescents spoke of positive reflections, challenges, and need for support 4 years on from the COVID-19 pandemic. Many adolescents shared their lived experiences for the first time with someone else and wished they would have the space and time to acknowledge this period of loss. Adolescents living with existing inequality and deprivation before the pandemic have reported sustained and exacerbated impacts during the pandemic, hence coproduced support for adolescents should be a priority.
MeSH term(s)	Adolescent ; Female ; Humans ; Male ; Mental Health ; London/epidemiology ; Pandemics ; COVID-19/epidemiology ; Health Inequities
Language	English
Publishing date	2024-04-02
Publishing country	England
Document type	Journal Article
ZDB-ID	2599832-8
ISSN	2044-6055 ; 2044-6055
ISSN (online)	2044-6055
ISSN	2044-6055
DOI	10.1136/bmjopen-2023-080161
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Article ; Online: Effects of the COVID-19 lockdown on mental health in a UK student sample.

Catling, J C / Bayley, A / Begum, Z / Wardzinski, C / Wood, A

BMC psychology

2022 Volume 10, Issue 1, Page(s) 118

Abstract: ... study assesses the impact of COVID-19 on student mental health.: Method: Four hundred and thirty four ... This research suggests that COVID-19 has had a major impact upon student mental health, and smartphone addiction ... a profound impact on both physical and mental health, particularly for young people.: Aims: The current ...

Abstract	Background: The COVID-19 pandemic and the resulting restrictions placed upon society have had a profound impact on both physical and mental health, particularly for young people. Aims: The current study assesses the impact of COVID-19 on student mental health. Method: Four hundred and thirty four first year Undergraduate students completed a battery of self-report questionnaires (PHQ-P, GAD-7 and SAS-SV) to assess for depression, anxiety and mobile phone addiction respectively with data being collected over a 2 year period. The data from each year was compared (216 and 218 students respectively). Results: A MANOVA revealed that COVID-19 had a significant impact on self-reported levels of depression, anxiety and smartphone addiction-which all significantly increased from the 2020 to the 2021 group. The percentage of students who had a score which warranted a classification of clinical depression increased from 30 to 44%, and for anxiety increased from 22 to 27%-those students who showed a comorbidity across the two rose from 12 to 21%. Smartphone addiction levels rose from 39 to 50%. Correlational analysis showed a significant relationship between Smartphone usage and depression and anxiety. Conclusions: This research suggests that COVID-19 has had a major impact upon student mental health, and smartphone addiction. The importance of identifying predictive factors of depression and anxiety is emphasised, and suggestions for intervention are discussed.
MeSH term(s)	Adolescent ; Anxiety/epidemiology ; COVID-19/epidemiology ; Communicable Disease Control ; Depression/epidemiology ; Humans ; Mental Health ; Pandemics ; Students/psychology ; United Kingdom/epidemiology
Language	English
Publishing date	2022-05-07
Publishing country	England
Document type	Journal Article
ZDB-ID	2705921-2
ISSN	2050-7283 ; 2050-7283
ISSN (online)	2050-7283
ISSN	2050-7283
DOI	10.1186/s40359-022-00732-9
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Article ; Online: The prevalence of common mental disorders across 18 ethnic groups in Britain during the COVID-19 pandemic: Evidence for Equality National Survey (EVENS).

Irizar, Patricia / Taylor, Harry / Kapadia, Dharmi / Pierce, Matthias / Bécares, Laia / Goodwin, Laura / Katikireddi, Srinivasa Vittal / Nazroo, James

Journal of affective disorders

2024 Volume 358, Page(s) 42–51

Abstract: Background: The COVID-19 pandemic negatively impacted mental health in the general population ... which may contribute to poorer mental health. We compare the prevalence of depression and anxiety across 18 ... in Britain. Ethnic minority people suffered disproportionately, in terms of health and economic outcomes ...

Abstract	Background: The COVID-19 pandemic negatively impacted mental health in the general population in Britain. Ethnic minority people suffered disproportionately, in terms of health and economic outcomes, which may contribute to poorer mental health. We compare the prevalence of depression and anxiety across 18 ethnic groups in Britain during the COVID-19 pandemic. Methods: Secondary analysis of cross-sectional data (February-November 2021) from 12,161 participants aged 18-60 years old (N with data on outcomes = 11,540 for depression & 11,825 for anxiety), obtained from the Evidence for Equality National Survey (EVENS). Data were weighted to account for selection bias and coverage bias. Weighted regression models examined ethnic differences in depression (Centre for Epidemiologic Studies Depression Scale) and anxiety (Generalised Anxiety Disorder-7). Effect modification analyses explored whether ethnic differences in outcomes were consistent within age and sex sub-groups. Results: Compared to White British people, greater odds of anxiety caseness (and greater anxiety symptoms) were observed for Arab (OR = 2.57; 95 % CI = 1.35-4.91), Mixed White and Black Caribbean (1.57; 1.07-2.30), any other Black (2.22, 1.28-3.87) and any other Mixed (1.58; 1.08-2.31) ethnic groups. Lower odds of depression caseness (and lower depressive symptoms) were identified for Chinese (0.63; 0.46-0.85), Black African (0.60; 0.46-0.79), and any other Asian (0.55; 0.42-0.72) ethnic groups. Limitations: Cross-sectional data limits the opportunity to identify changes in ethnic inequalities in mental health over time. Conclusions: We have identified certain ethnic groups who may require more targeted mental health support to ensure equitable recovery post-pandemic. Despite finding lower levels of depression for some ethnic groups, approximately one third of people within each ethnic group met criteria for depression.
MeSH term(s)	Humans ; COVID-19/ethnology ; United Kingdom/epidemiology ; United Kingdom/ethnology ; Adult ; Female ; Male ; Cross-Sectional Studies ; Prevalence ; Middle Aged ; Adolescent ; Ethnicity/statistics & numerical data ; Ethnicity/psychology ; Young Adult ; Depression/ethnology ; Depression/epidemiology ; SARS-CoV-2 ; Anxiety/ethnology ; Anxiety/epidemiology ; Mental Health/ethnology ; Mental Health/statistics & numerical data ; Anxiety Disorders/ethnology ; Anxiety Disorders/epidemiology
Language	English
Publishing date	2024-05-03
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	135449-8
ISSN	1573-2517 ; 0165-0327
ISSN (online)	1573-2517
ISSN	0165-0327
DOI	10.1016/j.jad.2024.05.026
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Article ; Online: Antidepressant drug prescription and incidence of COVID-19 in mental health outpatients: a retrospective cohort study.

Glebov, Oleg O / Mueller, Christoph / Stewart, Robert / Aarsland, Dag / Perera, Gayan

BMC medicine

2023 Volume 21, Issue 1, Page(s) 209

Abstract: ... in a cohort of community-dwelling adult mental health outpatients during the 1st wave of COVID-19 pandemic ... 19 test results when adjusted for socioeconomic parameters and physical health. This association was ... nature and the focus on a mental health patient cohort. A more definitive assessment of AD and SSRI ...

Abstract	Background: Currently, the main pharmaceutical intervention for COVID-19 is vaccination. While antidepressant (AD) drugs have shown some efficacy in treatment of symptomatic COVID-19, their preventative potential remains largely unexplored. Analysis of association between prescription of ADs and COVID-19 incidence in the population would be beneficial for assessing the utility of ADs in COVID-19 prevention. Methods: Retrospective study of association between AD prescription and COVID-19 diagnosis was performed in a cohort of community-dwelling adult mental health outpatients during the 1st wave of COVID-19 pandemic in the UK. Clinical record interactive search (CRIS) was performed for mentions of ADs within 3 months preceding admission to inpatient care of the South London and Maudsley (SLaM) NHS Foundation Trust. Incidence of positive COVID-19 tests upon admission and during inpatient treatment was the primary outcome measure. Results: AD mention was associated with approximately 40% lower incidence of positive COVID-19 test results when adjusted for socioeconomic parameters and physical health. This association was also observed for prescription of ADs of the selective serotonin reuptake inhibitor (SSRI) class. Conclusions: This preliminary study suggests that ADs, and SSRIs in particular, may be of benefit for preventing COVID-19 infection spread in the community. The key limitations of the study are its retrospective nature and the focus on a mental health patient cohort. A more definitive assessment of AD and SSRI preventative potential warrants prospective studies in the wider demographic.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Female ; Humans ; Male ; Middle Aged ; Young Adult ; Antidepressive Agents/therapeutic use ; COVID-19/diagnosis ; COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19 Testing ; Incidence ; Mental Disorders/drug therapy ; Outpatients/psychology ; Outpatients/statistics & numerical data ; Prescription Drugs/therapeutic use ; Retrospective Studies ; Selective Serotonin Reuptake Inhibitors/therapeutic use ; United Kingdom/epidemiology
Chemical Substances	Antidepressive Agents ; Prescription Drugs ; Selective Serotonin Reuptake Inhibitors
Language	English
Publishing date	2023-06-21
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2131669-7
ISSN	1741-7015 ; 1741-7015
ISSN (online)	1741-7015
ISSN	1741-7015
DOI	10.1186/s12916-023-02877-9
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