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  1. Article ; Online: Coronavirus disease 2019 (COVID-19) pneumonia in a hemodialysis patient: A case report.

    Huang, Luyan / Wang, Yiru / Wang, Lisheng / Lv, Yongman / Liu, Qingquan

    Medicine

    2020  Volume 99, Issue 27, Page(s) e20956

    Abstract: ... with end-stage renal disease who also suffer from COVID-19. In this report, we discuss the case of a hemodialysis patient ... Rationale: The 2019 novel coronavirus disease (COVID-19) causes a novel, atypical pneumonia ... The patient, who also had cardiovascular disease, had no history of contact with COVID-2019 patients ...

    Abstract Rationale: The 2019 novel coronavirus disease (COVID-19) causes a novel, atypical pneumonia that has brought huge public health challenges across the globe. There is limited data about patients with end-stage renal disease who also suffer from COVID-19. In this report, we discuss the case of a hemodialysis patient who developed COVID-19 pneumonia in the clinical course.
    Patient concerns: A 79-year-old man who had end-stage renal disease (ESRD) and was taking regular hemodialysis was admitted to hospital for a fever and dry cough. The patient, who also had cardiovascular disease, had no history of contact with COVID-2019 patients.
    Diagnosis: The patient was diagnosed with COVID-2019 by the reverse-transcriptase polymerase chain reaction (RT-PCR), and his pharyngeal swab for SARS-CoV-2 was positive.
    Intervention: The treatment was mainly supportive and the patient was intensively monitored. He was treated with oxygen, broad-spectrum antibiotics, antiviral drugs, and methylprednisolone. The patient took continuous renal replacement therapy (CRRT) every 2 days.
    Outcomes: After 19 days, an RT-PCR assay for SARS-CoV-2 was negative, and computed tomography (CT) of the patient's thorax indicated that the pulmonary inflammatory exudation was absorbed and pulmonary infection improved significantly. He was discharged on day 29 after recovering from COVID-2019 pneumonia.
    Lessons: The courses of disease and treatment options for this individual were significantly more complicated than those for ordinary patients. Therefore, it was necessary to monitor the condition of the patient closely and to protect the dialysis unit staff from being infected. Compared with other severe COVID-2019 cases, this patient recovered more quickly following treatment, which was likely due to the removal of inflammatory mediators by CRRT. This implies that blood purification might be an important option for hemodialysis patients with COVID-19.
    MeSH term(s) Aged ; Anti-Bacterial Agents/therapeutic use ; Anti-Inflammatory Agents/therapeutic use ; Antiviral Agents/therapeutic use ; Betacoronavirus ; COVID-19 ; Combined Modality Therapy ; Coronavirus Infections/complications ; Coronavirus Infections/drug therapy ; Coronavirus Infections/therapy ; Humans ; Kidney Failure, Chronic/complications ; Kidney Failure, Chronic/therapy ; Male ; Methylprednisolone/therapeutic use ; Oxygen Inhalation Therapy ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/therapy ; Renal Dialysis ; SARS-CoV-2
    Chemical Substances Anti-Bacterial Agents ; Anti-Inflammatory Agents ; Antiviral Agents ; Methylprednisolone (X4W7ZR7023)
    Keywords covid19
    Language English
    Publishing date 2020-07-06
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000020956
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Coronavirus disease 2019 (COVID-19) pneumonia in a hemodialysis patient ; A case report

    Huang, Luyan / Wang, Yiru / Wang, Lisheng / Lv, Yongman / Liu, Qingquan

    Medicine

    2020  Volume 99, Issue 27, Page(s) e20956

    Keywords General Medicine ; covid19
    Language English
    Publisher Ovid Technologies (Wolters Kluwer Health)
    Publishing country us
    Document type Article ; Online
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/md.0000000000020956
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Coronavirus disease 2019 (COVID-19) pneumonia in a hemodialysis patient: A case report

    Huang, Luyan / Wang, Yiru / Wang, Lisheng / Lv, Yongman / Liu, Qingquan

    Medicine (Baltimore)

    Abstract: ... with end-stage renal disease who also suffer from COVID-19. In this report, we discuss the case of a hemodialysis patient ... RATIONALE: The 2019 novel coronavirus disease (COVID-19) causes a novel, atypical pneumonia ... The patient, who also had cardiovascular disease, had no history of contact with COVID-2019 patients ...

    Abstract RATIONALE: The 2019 novel coronavirus disease (COVID-19) causes a novel, atypical pneumonia that has brought huge public health challenges across the globe. There is limited data about patients with end-stage renal disease who also suffer from COVID-19. In this report, we discuss the case of a hemodialysis patient who developed COVID-19 pneumonia in the clinical course. PATIENT CONCERNS: A 79-year-old man who had end-stage renal disease (ESRD) and was taking regular hemodialysis was admitted to hospital for a fever and dry cough. The patient, who also had cardiovascular disease, had no history of contact with COVID-2019 patients. DIAGNOSIS: The patient was diagnosed with COVID-2019 by the reverse-transcriptase polymerase chain reaction (RT-PCR), and his pharyngeal swab for SARS-CoV-2 was positive. INTERVENTION: The treatment was mainly supportive and the patient was intensively monitored. He was treated with oxygen, broad-spectrum antibiotics, antiviral drugs, and methylprednisolone. The patient took continuous renal replacement therapy (CRRT) every 2 days. OUTCOMES: After 19 days, an RT-PCR assay for SARS-CoV-2 was negative, and computed tomography (CT) of the patient's thorax indicated that the pulmonary inflammatory exudation was absorbed and pulmonary infection improved significantly. He was discharged on day 29 after recovering from COVID-2019 pneumonia. LESSONS: The courses of disease and treatment options for this individual were significantly more complicated than those for ordinary patients. Therefore, it was necessary to monitor the condition of the patient closely and to protect the dialysis unit staff from being infected. Compared with other severe COVID-2019 cases, this patient recovered more quickly following treatment, which was likely due to the removal of inflammatory mediators by CRRT. This implies that blood purification might be an important option for hemodialysis patients with COVID-19.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #619598
    Database COVID19

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  4. Article ; Online: A case of hemophagocytic lymphohistiocytosis in a hemodialysis patient with coronavirus disease 2019.

    Kaneko, Satoru / Inoue, Tsutomu / Tarumoto, Norihito / Haga, Yoshiyuki / Yokota, Kazuhiro / Yamaguchi, Hiroshi / Okada, Hirokazu

    CEN case reports

    2023  Volume 12, Issue 4, Page(s) 390–396

    Abstract: During the treatment of a patient on hemodialysis with severe coronavirus disease 2019 (COVID-19 ... pneumonia. However, the patient's condition worsened after the peak infection phase of COVID-19 ... the patient was weaned from extracorporeal membrane oxygenation, which was used to treat severe COVID-19 ...

    Abstract During the treatment of a patient on hemodialysis with severe coronavirus disease 2019 (COVID-19), the patient was weaned from extracorporeal membrane oxygenation, which was used to treat severe COVID-19 pneumonia. However, the patient's condition worsened after the peak infection phase of COVID-19 because of acute respiratory distress syndrome with suspected hemophagocytic lymphohistiocytosis (HLH). After a bone marrow biopsy confirmed the diagnosis, methylprednisolone pulse therapy, followed by combination therapy (including oral prednisolone and cyclosporine) was immediately administered, and the patient survived. Because HLH can occur a month or more after the onset of COVID-19, even if the viral load is reduced to the point of being undetectable by reverse transcriptase-polymerase chain reaction, it can be considered to correspond to the "post-acute COVID-19 syndrome," which has recently been proposed. Early intervention is necessary, because HLH can be fatal. Therefore, it is important to know that HLH can occur at any stage of COVID-19 and to pay attention to the patient's progress over time, including checking the HScore.
    MeSH term(s) Humans ; COVID-19/complications ; Lymphohistiocytosis, Hemophagocytic/complications ; Lymphohistiocytosis, Hemophagocytic/diagnosis ; Lymphohistiocytosis, Hemophagocytic/therapy ; Bone Marrow/pathology ; Spleen
    Language English
    Publishing date 2023-03-03
    Publishing country Japan
    Document type Case Reports ; Journal Article
    ZDB-ID 2660492-9
    ISSN 2192-4449 ; 2192-4449
    ISSN (online) 2192-4449
    ISSN 2192-4449
    DOI 10.1007/s13730-023-00776-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Coronavirus Disease 2019 in a Hemodialysis Patient.

    Yuan, Hai / Guo, E / Gao, Zhao / Hu, Fengqi / Lu, Li

    Blood purification

    2020  Volume 49, Issue 6, Page(s) 761–764

    Abstract: There has been a global outbreak of the coronavirus disease 2019 (COVID-19) since December 2019 ... of COVID-19 in maintenance HD patients are discussed in this report. ... the polymerase chain reaction of the pharyngeal swab for the -COVID-19 nucleic acid was positive. The patient developed ...

    Abstract There has been a global outbreak of the coronavirus disease 2019 (COVID-19) since December 2019. Here, we describe the case of a 49-year-old male undergoing maintenance hemodialysis (HD) who got infected with COVID-19 and our experience in performing HD for him. The patient's symptoms and lung imaging changes were atypical. However, his lymphocyte range decreased upon admission and the polymerase chain reaction of the pharyngeal swab for the -COVID-19 nucleic acid was positive. The patient developed respiratory failure and required mechanical ventilation 8 days after admission. In the end, he died from multiple organ dysfunction syndrome. The difficulties in diagnosis, infection control, and treatment of COVID-19 in maintenance HD patients are discussed in this report.
    MeSH term(s) Antiviral Agents/therapeutic use ; Betacoronavirus/isolation & purification ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques ; Combined Modality Therapy ; Coronavirus Infections/complications ; Coronavirus Infections/diagnosis ; Coronavirus Infections/drug therapy ; Coronavirus Infections/prevention & control ; Coronavirus Infections/therapy ; Cross Infection/prevention & control ; Diabetic Nephropathies/therapy ; Disease Progression ; Fatal Outcome ; Humans ; Infection Control/methods ; Infectious Disease Transmission, Patient-to-Professional/prevention & control ; Kidney Failure, Chronic/therapy ; Lung/diagnostic imaging ; Male ; Medical Waste Disposal/methods ; Middle Aged ; Multiple Organ Failure/etiology ; Pandemics/prevention & control ; Patient Isolation ; Pharynx/virology ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/therapy ; Renal Dialysis/methods ; Respiration, Artificial ; SARS-CoV-2 ; Symptom Assessment ; Tomography, X-Ray Computed
    Chemical Substances Antiviral Agents ; Medical Waste Disposal
    Keywords covid19
    Language English
    Publishing date 2020-04-27
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 605548-5
    ISSN 1421-9735 ; 0253-5068
    ISSN (online) 1421-9735
    ISSN 0253-5068
    DOI 10.1159/000507877
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Coronavirus Disease-2019 and the kidneys

    Eman Sobh / Ahmed Salama Al-Adl / Mohamed F Awadallah / Khloud Gamal Abdelsalam / Sohaila Sabry Awad / Amal M Surrati / Hani A Alhadrami

    Journal of Medical Sciences, Vol 42, Iss 4, Pp 153-

    A tragedy of reciprocal damage and management challenges

    2022  Volume 159

    Abstract: Coronavirus disease 2019 (COVID-19) has been reported to affect nearly all body systems. Kidney ... affection has been observed in several studies. The effect of COVID-19 on renal function is ... in COVID-19 are vital to avoid increased morbidity and mortality. Proper selection of drugs and fluid ...

    Abstract Coronavirus disease 2019 (COVID-19) has been reported to affect nearly all body systems. Kidney affection has been observed in several studies. The effect of COVID-19 on renal function is beyond that occurring in pneumonia or severe respiratory distress cases. Renal affection is attributed to several factors, including the mechanism of viral injury. Patients with preexisting kidney injury are at increased risk of infection. Early detection and management are crucial to avoid morbidity and mortality, prevent the spread and contamination of hemodialysis Units. Early detection and treatment of kidney involvement in COVID-19 are vital to avoid increased morbidity and mortality. Proper selection of drugs and fluid management is vital in cases with kidney involvement. This review aims to discuss the clinical and pathophysiological affection of the kidney in COVID-19.
    Keywords acute kidney injury ; chronic kidney disease ; coronavirus ; covid-19 ; kidney injury ; severe acute respiratory syndrome-coronavirus-2 ; Medicine ; R ; Medical emergencies. Critical care. Intensive care. First aid ; RC86-88.9
    Subject code 616
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Glucose-6-phosphate dehydrogenase deficiency presenting with rhabdomyolysis in a patient with coronavirus disease 2019 pneumonia: a case report.

    Yu, Regina / Chen, Chien-Rong / Evans, Darci / Qing, Xin / Gotesman, Moran / Chandramohan, Gangadarshni / Kallay, Thomas / Lin, Henry J / Pedigo, Tiffany P

    Journal of medical case reports

    2022  Volume 16, Issue 1, Page(s) 106

    Abstract: ... the pandemic. We report the uncommon occurrence of coronavirus disease 2019 pneumonia, severe rhabdomyolysis ... predisposing factor for rhabdomyolysis. Rhabdomyolysis with coronavirus disease 2019 has been increasingly seen during ... and acute renal failure in the setting of glucose-6-phosphate dehydrogenase deficiency.: Case ...

    Abstract Background: Glucose-6-phosphate dehydrogenase deficiency is a rarely recognized predisposing factor for rhabdomyolysis. Rhabdomyolysis with coronavirus disease 2019 has been increasingly seen during the pandemic. We report the uncommon occurrence of coronavirus disease 2019 pneumonia, severe rhabdomyolysis, and acute renal failure in the setting of glucose-6-phosphate dehydrogenase deficiency.
    Case presentation: A 19-year-old African American male presented with myalgias, diaphoresis, and dark urine. Testing for severe acute respiratory syndrome coronavirus 2 was positive. He had severe rhabdomyolysis with creatine kinase levels up to 346,695 U/L. He was oliguric and eventually required hemodialysis. Progressive hypoxemia, methemoglobinemia, and hemolytic anemia occurred following one dose of rasburicase for hyperuricemia. Glucose-6-phosphate dehydrogenase deficiency was diagnosed. Full recovery followed a single volume exchange transfusion and simple packed red blood cell transfusions.
    Conclusions: Glucose-6-phosphate dehydrogenase deficiency may predispose individuals to rhabdomyolysis due to severe acute respiratory syndrome coronavirus 2, presumably due to altered host responses to viral oxidative stress. Early screening for glucose-6-phosphate dehydrogenase deficiency can be useful for management of patients with rhabdomyolysis.
    MeSH term(s) Adult ; COVID-19/complications ; Glucosephosphate Dehydrogenase Deficiency/complications ; Glucosephosphate Dehydrogenase Deficiency/diagnosis ; Humans ; Male ; Methemoglobinemia/complications ; Methemoglobinemia/diagnosis ; Pneumonia/complications ; Rhabdomyolysis/etiology ; Young Adult
    Language English
    Publishing date 2022-03-14
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2269805-X
    ISSN 1752-1947 ; 1752-1947
    ISSN (online) 1752-1947
    ISSN 1752-1947
    DOI 10.1186/s13256-022-03322-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Hemoperfusion techniques using Jafron HA330 cartridge combined with BBraun Dialog+ dialysis machine in patient with coronavirus disease 2019 pneumonia and septic shock: a case report.

    Hartomuljono, Adrian / Sugiarto, Adhrie / Jennefer

    Journal of medical case reports

    2023  Volume 17, Issue 1, Page(s) 156

    Abstract: ... increasingly intense, especially in coronavirus disease 2019 patients who are already known to the general ... for the BBraun Dialog+ dialysis machine. This case report presents an 84-year-old Asian man with septic shock due ... to pneumonia, congestive heart failure, and acute chronic kidney disease accompanied by fluid overload. After ...

    Abstract Background: The use of hemoperfusion for cytokine removal and inflammatory mediators is increasingly intense, especially in coronavirus disease 2019 patients who are already known to the general public for having cytokine storms. However, we have known about these cytokine storms for a long time in the critical care world. One of the modalities to remove cytokines is to use filtration and adsorption techniques with continuous renal replacement therapy. The use of continuous renal replacement therapy is usually constrained by its very high cost compared with standard care, especially in Indonesia, where health costs are covered by national health insurance. In this case, we use hemodialysis and hemoperfusion, using a dialysis machine, which is more cost-effective and easy to use.
    Case presentation: We used the Jafron HA330 cartridge, modified for the BBraun Dialog+ dialysis machine. This case report presents an 84-year-old Asian man with septic shock due to pneumonia, congestive heart failure, and acute chronic kidney disease accompanied by fluid overload. After undergoing hemodialysis and hemoperfusion separately, there was a gradual and significant clinical improvement. Clinical indicators, including the vasopressor inotropic score and infection markers, should all be considered when deciding whether to begin hemodialysis and hemoperfusion.
    Conclusion: In general, using hemoperfusion to treat septic shock patients can reduce the length of stay in the intensive care unit, and morbidity and mortality.
    MeSH term(s) Male ; Humans ; Aged, 80 and over ; Shock, Septic/complications ; Shock, Septic/therapy ; Hemoperfusion/methods ; Cytokine Release Syndrome ; Renal Dialysis/methods ; COVID-19/therapy ; Pneumonia
    Language English
    Publishing date 2023-04-08
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2269805-X
    ISSN 1752-1947 ; 1752-1947
    ISSN (online) 1752-1947
    ISSN 1752-1947
    DOI 10.1186/s13256-023-03851-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Hemoperfusion techniques using Jafron HA330 cartridge combined with BBraun Dialog+ dialysis machine in patient with coronavirus disease 2019 pneumonia and septic shock

    Adrian Hartomuljono / Adhrie Sugiarto / Jennefer

    Journal of Medical Case Reports, Vol 17, Iss 1, Pp 1-

    a case report

    2023  Volume 6

    Abstract: ... increasingly intense, especially in coronavirus disease 2019 patients who are already known to the general ... Dialog+ dialysis machine. This case report presents an 84-year-old Asian man with septic shock due ... to pneumonia, congestive heart failure, and acute chronic kidney disease accompanied by fluid overload. After ...

    Abstract Abstract Background The use of hemoperfusion for cytokine removal and inflammatory mediators is increasingly intense, especially in coronavirus disease 2019 patients who are already known to the general public for having cytokine storms. However, we have known about these cytokine storms for a long time in the critical care world. One of the modalities to remove cytokines is to use filtration and adsorption techniques with continuous renal replacement therapy. The use of continuous renal replacement therapy is usually constrained by its very high cost compared with standard care, especially in Indonesia, where health costs are covered by national health insurance. In this case, we use hemodialysis and hemoperfusion, using a dialysis machine, which is more cost-effective and easy to use. Case presentation We used the Jafron HA330 cartridge, modified for the BBraun Dialog+ dialysis machine. This case report presents an 84-year-old Asian man with septic shock due to pneumonia, congestive heart failure, and acute chronic kidney disease accompanied by fluid overload. After undergoing hemodialysis and hemoperfusion separately, there was a gradual and significant clinical improvement. Clinical indicators, including the vasopressor inotropic score and infection markers, should all be considered when deciding whether to begin hemodialysis and hemoperfusion. Conclusion In general, using hemoperfusion to treat septic shock patients can reduce the length of stay in the intensive care unit, and morbidity and mortality.
    Keywords Hemodialysis ; Hemoperfusion ; Septic shock ; COVID-19 ; Chronic kidney disease ; Medicine ; R
    Subject code 610 ; 616
    Language English
    Publishing date 2023-04-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Glucose-6-phosphate dehydrogenase deficiency presenting with rhabdomyolysis in a patient with coronavirus disease 2019 pneumonia

    Regina Yu / Chien-Rong Chen / Darci Evans / Xin Qing / Moran Gotesman / Gangadarshni Chandramohan / Thomas Kallay / Henry J. Lin / Tiffany P. Pedigo

    Journal of Medical Case Reports, Vol 16, Iss 1, Pp 1-

    a case report

    2022  Volume 5

    Abstract: ... the pandemic. We report the uncommon occurrence of coronavirus disease 2019 pneumonia, severe rhabdomyolysis ... predisposing factor for rhabdomyolysis. Rhabdomyolysis with coronavirus disease 2019 has been increasingly seen during ... and acute renal failure in the setting of glucose-6-phosphate dehydrogenase deficiency. Case ...

    Abstract Abstract Background Glucose-6-phosphate dehydrogenase deficiency is a rarely recognized predisposing factor for rhabdomyolysis. Rhabdomyolysis with coronavirus disease 2019 has been increasingly seen during the pandemic. We report the uncommon occurrence of coronavirus disease 2019 pneumonia, severe rhabdomyolysis, and acute renal failure in the setting of glucose-6-phosphate dehydrogenase deficiency. Case presentation A 19-year-old African American male presented with myalgias, diaphoresis, and dark urine. Testing for severe acute respiratory syndrome coronavirus 2 was positive. He had severe rhabdomyolysis with creatine kinase levels up to 346,695 U/L. He was oliguric and eventually required hemodialysis. Progressive hypoxemia, methemoglobinemia, and hemolytic anemia occurred following one dose of rasburicase for hyperuricemia. Glucose-6-phosphate dehydrogenase deficiency was diagnosed. Full recovery followed a single volume exchange transfusion and simple packed red blood cell transfusions. Conclusions Glucose-6-phosphate dehydrogenase deficiency may predispose individuals to rhabdomyolysis due to severe acute respiratory syndrome coronavirus 2, presumably due to altered host responses to viral oxidative stress. Early screening for glucose-6-phosphate dehydrogenase deficiency can be useful for management of patients with rhabdomyolysis.
    Keywords Rhabdomyolysis ; G6PD deficiency ; Acute kidney injury ; COVID-19 ; SARS-CoV-2 ; Methemoglobinemia ; Medicine ; R
    Language English
    Publishing date 2022-03-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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