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Article ; Online: Proteinuria in COVID-19: prevalence, characterization and prognostic role.

Huart, Justine / Bouquegneau, Antoine / Lutteri, Laurence / Erpicum, Pauline / Grosch, Stéphanie / Résimont, Guillaume / Wiesen, Patricia / Bovy, Christophe / Krzesinski, Jean-Marie / Thys, Marie / Lambermont, Bernard / Misset, Benoît / Pottel, Hans / Mariat, Christophe / Cavalier, Etienne / Burtey, Stéphane / Jouret, François / Delanaye, Pierre

Journal of nephrology

2021  Volume 34, Issue 2, Page(s) 355–364

Abstract: ... in patients with COVID-19. Its characterization suggests a tubular origin, with increased urinary α ... dipstick tests have been frequently used thus far. Here, the quantification and characterization ... Background: Proteinuria has been commonly reported in patients with COVID-19. However, only ...

Abstract Background: Proteinuria has been commonly reported in patients with COVID-19. However, only dipstick tests have been frequently used thus far. Here, the quantification and characterization of proteinuria were investigated and their association with mortality was assessed.
Methods: This retrospective, observational, single center study included 153 patients, hospitalized with COVID-19 between March 28th and April 30th, 2020, in whom total proteinuria and urinary α
Results: According to the Kidney Disease Improving Global Outcomes staging, 14% (n = 21) of the patients had category 1 proteinuria (< 150 mg/g of urine creatinine), 42% (n = 64) had category 2 (between 150 and 500 mg/g) and 44% (n = 68) had category 3 proteinuria (over 500 mg/g). Urine α
Conclusions: Proteinuria is frequent in patients with COVID-19. Its characterization suggests a tubular origin, with increased urinary α
MeSH term(s) Aged ; Aged, 80 and over ; Belgium/epidemiology ; Biomarkers/urine ; COVID-19/complications ; COVID-19/epidemiology ; COVID-19/urine ; Female ; Humans ; Male ; Middle Aged ; Prevalence ; Prognosis ; Proteinuria/epidemiology ; Proteinuria/etiology ; Proteinuria/urine ; Retrospective Studies ; Survival Rate/trends
Chemical Substances Biomarkers
Language English
Publishing date 2021-01-23
Publishing country Italy
Document type Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
ZDB-ID 1093991-x
ISSN 1724-6059 ; 1120-3625 ; 1121-8428
ISSN (online) 1724-6059
ISSN 1120-3625 ; 1121-8428
DOI 10.1007/s40620-020-00931-w
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