Article: Discovery of TAK-272: A Novel, Potent, and Orally Active Renin Inhibitor.
ACS medicinal chemistry letters
2016 Volume 7, Issue 10, Page(s) 933–938
Abstract: The aspartic proteinase renin is an attractive target for the treatment of hypertension and ... cardiovascular/renal disease such as chronic kidney disease and heart failure. We introduced an S1' site binder ...
| Abstract | The aspartic proteinase renin is an attractive target for the treatment of hypertension and cardiovascular/renal disease such as chronic kidney disease and heart failure. We introduced an S1' site binder into the lead compound |
|---|---|
| Language | English |
| Publishing date | 2016-09-12 |
| Publishing country | United States |
| Document type | Journal Article |
| ISSN | 1948-5875 |
| ISSN | 1948-5875 |
| DOI | 10.1021/acsmedchemlett.6b00251 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
More links
Kategorien
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.
Inter-library loan at ZB MED
Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.