Article ; Online: Morbidity and Mortality in Patients with Perioperative COVID-19 Infection: Prospective Cohort in General, Gastroesophagic, Hepatobiliary, and Colorectal Surgery.
2021 Volume 45, Issue 6, Page(s) 1652–1662
Abstract: ... Conclusions: 30-day mortality and surgical complications are higher in patients with perioperative COVID-19 ... of consecutive patients who required a general, gastroesophageal, hepatobiliary, colorectal, or emergency surgery ... day mortality was 12.8% and 1.4% in patients with and without COVID-19 infection, respectively (p < 0 ...
| Abstract | Background: Severe acute respiratory syndrome due to coronavirus 2 has rapidly spread worldwide in an unprecedented pandemic. Patients with an ongoing COVID-19 infection requiring surgery have higher risk of mortality and complications. This study describes the mortality and morbidity in patients with perioperative COVID-19 infection undergoing elective and emergency surgeries. Methods: Prospective cohort of consecutive patients who required a general, gastroesophageal, hepatobiliary, colorectal, or emergency surgery during COVID-19 pandemic at an academic teaching hospital. The primary outcome was 30-day mortality and major complications. Secondary outcomes were specific respiratory mortality and complications. Results: A total of 701 patients underwent surgery, 39 (5.6%) with a perioperative COVID-19 infection. 30-day mortality was 12.8% and 1.4% in patients with and without COVID-19 infection, respectively (p < 0.001). Major surgical complications occurred in 25.6% and 6.8% in patients with and without COVID-19 infection, respectively (p < 0.001). Respiratory complications occurred in 30.8% and 1.4% in patients with and without COVID-19 infection, respectively (p < 0.001). Mortality due to a respiratory complication was 100% and 11.1% in patients with and without COVID-19 infection, respectively (p < 0.006). Conclusions: 30-day mortality and surgical complications are higher in patients with perioperative COVID-19 infection. Indications for elective surgery need to be reserved for non-deferrable procedures in order to avoid unnecessary risks of non-urgent procedures. |
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| MeSH term(s) | Biliary Tract Surgical Procedures/adverse effects ; Biliary Tract Surgical Procedures/mortality ; COVID-19/complications ; Colorectal Surgery/adverse effects ; Colorectal Surgery/mortality ; Female ; Hospital Mortality ; Humans ; Male ; Morbidity ; Pandemics ; Preoperative Period ; Prospective Studies ; SARS-CoV-2 ; Splenectomy/adverse effects ; Splenectomy/mortality | |||||
| Language | English | |||||
| Publishing date | 2021-03-21 | |||||
| Publishing country | United States | |||||
| Document type | Journal Article | |||||
| ZDB-ID | 224043-9 | |||||
| ISSN | 1432-2323 ; 0364-2313 | |||||
| ISSN (online) | 1432-2323 | |||||
| ISSN | 0364-2313 | |||||
| DOI | 10.1007/s00268-021-06068-6 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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