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Article ; Online: Clinical characteristics and outcomes of critically ill patients with COVID-19 in Kobe, Japan: a single-center, retrospective, observational study.

Ito, Jiro / Seo, Ryutaro / Kawakami, Daisuke / Matsuoka, Yoshinori / Ouchi, Kenjiro / Nonami, Suguru / Miyoshi, Yusuke / Tatebe, Masao / Tsuchida, Takahiro / Asaka, Yoko / Yanai, Machi / Ueta, Hiroshi / Shimozono, Takahiro / Mima, Hiroyuki / Doi, Asako / Tomii, Keisuke / Ariyoshi, Koichi

Journal of anesthesia

2021  Volume 35, Issue 2, Page(s) 213–221

Abstract: ... ICU) in Kobe, Japan.: Methods: This retrospective observational study included critically ill COVID ... outcomes of critically ill COVID-19 patients and the capacity of a COVID-19-dedicated intensive care unit ... worldwide. Data regarding critically ill COVID-19 patients and their demand of critical care services ...

Abstract Purpose: Coronavirus disease 2019 (COVID-19) has placed a great burden on critical care services worldwide. Data regarding critically ill COVID-19 patients and their demand of critical care services outside of initial COVID-19 epicenters are lacking. This study described clinical characteristics and outcomes of critically ill COVID-19 patients and the capacity of a COVID-19-dedicated intensive care unit (ICU) in Kobe, Japan.
Methods: This retrospective observational study included critically ill COVID-19 patients admitted to a 14-bed COVID-19-dedicated ICU in Kobe between March 3, 2020 and June 21, 2020. Clinical and daily ICU occupancy data were obtained from electrical medical records. The last follow-up day was June 28, 2020.
Results: Of 32 patients included, the median hospital follow-up period was 27 (interquartile range 19-50) days. The median age was 68 (57-76) years; 23 (72%) were men and 25 (78%) had at least one comorbidity. Nineteen (59%) patients received invasive mechanical ventilation for a median duration of 14 (8-27) days. Until all patients were discharged from the ICU on June 5, 2020, the median daily ICU occupancy was 50% (36-71%). As of June 28, 2020, six (19%) died during hospitalization. Of 26 (81%) survivors, 23 (72%) were discharged from the hospital and three (9%) remained in the hospital.
Conclusion: During the first months of the outbreak in Kobe, most critically ill patients were men aged ≥ 60 years with at least one comorbidity and on mechanical ventilation; the ICU capacity was not strained, and the case-fatality rate was 19%.
MeSH term(s) Aged ; COVID-19 ; Critical Illness ; Humans ; Intensive Care Units ; Japan ; Male ; Respiration, Artificial ; Retrospective Studies ; SARS-CoV-2
Language English
Publishing date 2021-01-23
Publishing country Japan
Document type Journal Article ; Observational Study
ZDB-ID 1107821-2
ISSN 1438-8359 ; 0913-8668
ISSN (online) 1438-8359
ISSN 0913-8668
DOI 10.1007/s00540-021-02897-w
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