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  1. Article ; Online: Posttraumatic Stress Disorder in Patients After Severe COVID-19 Infection.

    Janiri, Delfina / Carfì, Angelo / Kotzalidis, Georgios D / Bernabei, Roberto / Landi, Francesco / Sani, Gabriele

    JAMA psychiatry

    2021  Volume 78, Issue 5, Page(s) 567–569

    MeSH term(s) Adult ; Aged ; COVID-19/epidemiology ; COVID-19/psychology ; Cross-Sectional Studies ; Emergency Service, Hospital/statistics & numerical data ; Female ; Humans ; Italy/epidemiology ; Length of Stay/statistics & numerical data ; Male ; Middle Aged ; Pandemics ; SARS-CoV-2 ; Severity of Illness Index ; Stress Disorders, Post-Traumatic/epidemiology ; Stress Disorders, Post-Traumatic/etiology
    Language English
    Publishing date 2021-02-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2701203-7
    ISSN 2168-6238 ; 2168-622X
    ISSN (online) 2168-6238
    ISSN 2168-622X
    DOI 10.1001/jamapsychiatry.2021.0109
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  2. Article ; Online: Posttraumatic Stress Symptoms in Patients With Cancer During the COVID-19 Pandemic: A One-Year Longitudinal Study.

    Bastien, Etienne / Lefèvre-Arbogast, Sophie / Lequesne, Justine / Gernier, François / Cherifi, François / Rigal, Olivier / Guittet, Lydia / Grellard, Jean-Michel / Binarelli, Giulia / Lange, Marie / Fernette, Marie / Tron, Laure / Morel, Adeline / Richard, Doriane / Griffon, Bénédicte / Leconte, Alexandra / Quilan, Florian / Pépin, Louis-Ferdinand / Jardin, Fabrice /
    Leheurteur, Marianne / Faveyrial, Audrey / Clarisse, Bénédicte / Joly, Florence

    Journal of the National Comprehensive Cancer Network : JNCCN

    2023  Volume 21, Issue 3, Page(s) 265–272.e7

    Abstract: ... of the COVID-19 pandemic. We studied the prevalence and evolution of posttraumatic stress symptoms (PTSS ... Longitudinal analyses involved 386 patients with at least one PTSS assessment after baseline (median age, 63 ... on their quality of life, cognitive complaints, insomnia, and COVID-19 lockdown experience.: Results ...

    Abstract Background: Patients with cancer may be particularly vulnerable to psychological consequences of the COVID-19 pandemic. We studied the prevalence and evolution of posttraumatic stress symptoms (PTSS) in patients with cancer during the pandemic waves, and we investigated factors associated with high symptoms.
    Methods: COVIPACT is a 1-year longitudinal prospective study of French patients with solid/hematologic malignancies receiving treatment during the first nationwide lockdown. PTSS were measured every 3 months from April 2020 using the Impact of Event Scale-Revised. Patients also completed questionnaires on their quality of life, cognitive complaints, insomnia, and COVID-19 lockdown experience.
    Results: Longitudinal analyses involved 386 patients with at least one PTSS assessment after baseline (median age, 63 years; 76% female). Among them, 21.5% had moderate/severe PTSS during the first lockdown. The rate of patients reporting PTSS decreased at lockdown release (13.6%), increased again at second lockdown (23.2%), and slightly declined from the second release period (22.7%) to the third lockdown (17.5%). Patients were grouped into 3 trajectories of evolution. Most patients had stable low symptoms throughout the period, 6% had high baseline symptoms slowly decreasing over time, and 17.6% had moderate symptoms worsening during the second lockdown. Female sex, feeling socially isolated, worrying about COVID-19 infection, and using psychotropic drugs were associated with PTSS. PTSS were associated with impaired quality of life, sleep, and cognition.
    Conclusions: Approximately one-fourth of patients with cancer experienced high and persistent PTSS over the first year of the COVID-19 pandemic and may benefit from psychological support.
    Clinicaltrials: gov identifier: NCT04366154.
    MeSH term(s) Female ; Humans ; Male ; Middle Aged ; Communicable Disease Control ; COVID-19/epidemiology ; Longitudinal Studies ; Neoplasms/epidemiology ; Pandemics ; Prospective Studies ; Quality of Life/psychology ; Stress Disorders, Post-Traumatic/diagnosis ; Stress Disorders, Post-Traumatic/epidemiology ; Stress Disorders, Post-Traumatic/psychology
    Language English
    Publishing date 2023-02-21
    Publishing country United States
    Document type Clinical Trial ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2250759-0
    ISSN 1540-1413 ; 1540-1405
    ISSN (online) 1540-1413
    ISSN 1540-1405
    DOI 10.6004/jnccn.2023.7085
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  3. Article: Anxiety and posttraumatic stress in post-acute sequelae of COVID-19: prevalence, characteristics, comorbidity, and clinical correlates.

    Ferrando, Stephen J / Lynch, Sean / Ferrando, Nicole / Dornbush, Rhea / Shahar, Sivan / Klepacz, Lidia

    Frontiers in psychiatry

    2023  Volume 14, Page(s) 1160852

    Abstract: ... of 3 individuals after COVID-19 infection. They are highly comorbid with each other as well ... post-traumatic stress disorder questionnaire for DSM5 (PCL5) were utilized to measure anxiety and PTSD symptoms. Established ... with acute and post-acute sequelae of COVID-19 (PASC).: Purpose: This study aimed to document the cross ...

    Abstract Background: Anxiety and post-traumatic stress symptoms have been reported in association with acute and post-acute sequelae of COVID-19 (PASC).
    Purpose: This study aimed to document the cross-sectional prevalence, characteristics and clinical correlates of anxiety and post-traumatic stress in a study of neuropsychiatric sequelae of COVID-19.
    Method: 75 participants recruited from a post-COVID-19 recovery program and the community were assessed for sociodemographic, medical, psychiatric, and neurocognitive symptoms and performance. The generalized anxiety questionnaire-7 (GAD-7) and post-traumatic stress disorder questionnaire for DSM5 (PCL5) were utilized to measure anxiety and PTSD symptoms. Established cutoff scoring for the GAD-7 and algorithm-based scoring of the PCL5 were utilized to determine clinically significant anxiety symptoms and PTSD, respectively.
    Results: The cohort was 71% female, 36% ethnic minority, with the main age of 43.5 years, 80% employment, 40% with the prior psychiatric treatment history and 2/3 seeking post-COVID care for PASC. Clinically significant anxiety symptoms were found in 31% and PTSD was found in 29% of the cohort. Nervousness and excessive worry were the most prominent anxiety symptoms, while changes in mood/cognition and avoidance were most frequent in PTSD. There was a high degree of comorbidity between clinically significant anxiety symptoms, PTSD, depression and fatigue. In logistic regression, acute COVID illness severity, prior psychiatric history, and memory complaints (but not objective neuropsychological performance) predicted clinically significant anxiety symptoms and/or PTSD.
    Conclusion: Clinically significant anxiety and PTSD are found in approximately 1 of 3 individuals after COVID-19 infection. They are highly comorbid with each other as well as with depression and fatigue. All patients seeking care for PASC should be screened for these neuropsychiatric complications. Symptoms of worry, nervousness, subjective changes in mood, and cognition as well as behavioral avoidance are particularly important targets of clinical intervention.
    Language English
    Publishing date 2023-06-02
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2023.1160852
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  4. Article ; Online: Evaluation of depression, anxiety and posttraumatic stress response levels of children and adolescents treated with COVID-19.

    Taskesen, Bekir / Kardas, Omer / Yılmaz, Kamil

    European journal of pediatrics

    2022  Volume 182, Issue 2, Page(s) 567–574

    Abstract: ... in paediatric patients' post-COVID-19 infection. A total of two hundred consecutive patients aged 8 to 18 years ... four percent of patients' CPTS-RI was above the normal limit, while 4% had a severe stress reaction ... related disorders (SCARED) to evaluate their post-COVID-19 infection mental health state. In the study ...

    Abstract We aimed to evaluate stress level reactions to depression, anxiety, and posttraumatic stress in paediatric patients' post-COVID-19 infection. A total of two hundred consecutive patients aged 8 to 18 years were prospectively enrolled in the study between March 2020 and June 2021. One hundred patients were diagnosed with a positive COVID-PCR test and had inpatient management. Another hundred patients had positive COVID-PCR results and completed their care and isolation for 14 days at home. We used the child posttraumatic stress reaction index (CPTS-RI), child depression inventory (CDI), and screen for child anxiety-related disorders (SCARED) to evaluate their post-COVID-19 infection mental health state. In the study population, the mean age was 13.4 years, and 50.5% were male. Sixty-seven patients were paediatric, and the rest were adolescents. Based on our scaling system, 10% of patients had depression. Forty-one percent of patients had at least one high subscale of SCARED. Forty-four percent of patients' CPTS-RI was above the normal limit, while 4% had a severe stress reaction level. In the female patient population, SCARED and CPTS-RI were significantly high (p = 0.01). There was no significant correlation between hospitalization duration and test scores. The CPTS-RI score was significantly higher in the outpatient group than in the other groups (p = 0.01). The inpatient group had significantly higher social phobia, while the outpatient group had significantly higher school phobia (p = 0.01 and p = 0.05, respectively).
    Conclusion: The present study showed that COVID-19 infection is a significant risk factor for psychopathology in children and adolescents.
    What is known: • COVID-19 causes multiple physical complications in the body along with significant harmful physiologic mental health effects. After being diagnosed with COVID-19, paediatric and adolescent patients have been engaging in social isolation. • Shutdowns, school closings, minimizing social interaction, and isolating behaviour are some of the measures used to control the pandemic. For kids to develop into healthy individuals, they need social interaction and a safe environment.
    What is new: • The present study showed that COVID-19 infection is a significant risk factor for childhood and adolescent psychopathology. Based on our scaling system, 10% of patients had depression. Forty-four percent of patients' CPTS-RI was above the normal limit, while 4% had a severe stress reaction level. In the female patient population, SCARED and CPTS-RI were significantly high. • These patients need to be evaluated and monitored by paediatric and adolescent psychiatry clinics simultaneously with paediatric clinics.
    MeSH term(s) Humans ; Child ; Male ; Adolescent ; Female ; Stress Disorders, Post-Traumatic/diagnosis ; Stress Disorders, Post-Traumatic/epidemiology ; Stress Disorders, Post-Traumatic/etiology ; Depression/diagnosis ; Depression/etiology ; Depression/epidemiology ; COVID-19/diagnosis ; COVID-19/epidemiology ; Anxiety/diagnosis ; Anxiety/etiology ; Anxiety/epidemiology ; Phobic Disorders/psychology
    Language English
    Publishing date 2022-11-16
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 194196-3
    ISSN 1432-1076 ; 0340-6199 ; 0943-9676
    ISSN (online) 1432-1076
    ISSN 0340-6199 ; 0943-9676
    DOI 10.1007/s00431-022-04713-3
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  5. Article ; Online: Global Prevalence of Posttraumatic Stress Disorder (PTSD) during and after Coronavirus Pandemic

    Maryam Salmanian / Mona Salehi / Zahra Hooshyari

    Iranian Journal of Psychiatry, Vol 15, Iss 3, Pp 252-

    A Study Protocol for a Systematic Review and Meta-Analysis

    2020  Volume 255

    Abstract: ... during and after infectious disease pandemics, especially COVID-19. The findings of this study can be ... syndrome (MERS), and COVID-19 epidemics have shown PTSD can occur during and after infectious diseases ... However, more studies are needed to explore PTSD during and after COVID-19 outbreak. The objective of this study ...

    Abstract Objective: Studies conducted on severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), and COVID-19 epidemics have shown PTSD can occur during and after infectious diseases. However, more studies are needed to explore PTSD during and after COVID-19 outbreak. The objective of this study is to provide a protocol of systematic review and meta-analysis to report the global prevalence of PTSD during and after coronavirus pandemics among general population, health care workers, survivors, or patients with coronaviruses. Method: We include all studies that reported the prevalence of PTSD during and after coronavirus pandemics and search databases, including Web of Science, PubMed, Scopus, Embase, and Google Scholar from first of November 2002 to May 18, 2020. Two authors independently use relevant checklists to quality assessment of the included studies and extract data. We use the graphical methods and fixed or random effect models to aggregate prevalence estimates. Also, we will assess heterogeneity between the included studies using the I2 heterogeneity statistic and use subgroup and sensitivity analysis to assess the sources of heterogeneity. Discussion: We infer that PTSD is a common experience during and after infectious disease pandemics, especially COVID-19. The findings of this study can be used by health policymakers and other stakeholders and will provide a path to future studies.
    Keywords Psychiatry ; RC435-571 ; covid19
    Subject code 150
    Language English
    Publishing date 2020-07-01T00:00:00Z
    Publisher Tehran University of Medical Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: Global prevalence of posttraumatic stress disorder (PTSD) during and after coronavirus pandemic: A study protocol for a systematic review and meta-analysis

    Salmanian, M. / Salehi, M. / Hooshyari, Z.

    Iranian Journal of Psychiatry

    Abstract: ... during and after infectious disease pandemics, especially COVID-19 The findings of this study can be used ... syndrome (MERS), and COVID-19 epidemics have shown PTSD can occur during and after infectious diseases ... However, more studies are needed to explore PTSD during and after COVID-19 outbreak The objective of this study ...

    Abstract Objective: Studies conducted on severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), and COVID-19 epidemics have shown PTSD can occur during and after infectious diseases However, more studies are needed to explore PTSD during and after COVID-19 outbreak The objective of this study is to provide a protocol of systematic review and meta-analysis to report the global prevalence of PTSD during and after coronavirus pandemics among general population, health care workers, survivors, or patients with coronaviruses Method: We include all studies that reported the prevalence of PTSD during and after coronavirus pandemics and search databases, including Web of Science, PubMed, Scopus, Embase, and Google Scholar from first of November 2002 to May 18, 2020 Two authors independently use relevant checklists to quality assessment of the included studies and extract data We use the graphical methods and fixed or random effect models to aggregate prevalence estimates Also, we will assess heterogeneity between the included studies using the I2 heterogeneity statistic and use subgroup and sensitivity analysis to assess the sources of heterogeneity Discussion: We infer that PTSD is a common experience during and after infectious disease pandemics, especially COVID-19 The findings of this study can be used by health policymakers and other stakeholders and will provide a path to future studies
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #734711
    Database COVID19

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