Article ; Online: COVID-19 Manifesting as Renal Allograft Dysfunction, Acute Pancreatitis, and Thrombotic Microangiopathy: A Case Report.
2020 Volume 53, Issue 4, Page(s) 1211–1214
Abstract: ... thrombotic microangiopathy on rare occasions in native kidneys of patients with COVID-19. Here, we report the first case ... in both the general population and kidney transplant recipients. Acute kidney injury is a known complication of COVID-19 and ... acute pancreatitis and clinical features of microangiopathic hemolytic anemia. The patient recovered ...
| Abstract | Coronavirus disease 2019 (COVID-19) is associated with high morbidity and mortality worldwide in both the general population and kidney transplant recipients. Acute kidney injury is a known complication of COVID-19 and appears to most commonly manifest as acute tubular injury on renal biopsy. Coagulopathy associated with COVID-19 is a known but poorly understood complication that has been reported to cause thrombotic microangiopathy on rare occasions in native kidneys of patients with COVID-19. Here, we report the first case of biopsy-proven thrombotic microangiopathy in a kidney transplant recipient with COVID-19 who developed acute pancreatitis and clinical features of microangiopathic hemolytic anemia. The patient recovered with supportive care alone. |
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| MeSH term(s) | COVID-19/complications ; COVID-19/diagnosis ; COVID-19/virology ; Creatinine/blood ; Female ; Humans ; Kidney/pathology ; Kidney Failure, Chronic/complications ; Kidney Failure, Chronic/therapy ; Kidney Transplantation/adverse effects ; Middle Aged ; Pancreatitis/diagnosis ; Pancreatitis/etiology ; Platelet Count ; SARS-CoV-2/isolation & purification ; Tacrolimus/blood ; Tacrolimus/therapeutic use ; Thrombotic Microangiopathies/diagnosis ; Thrombotic Microangiopathies/etiology ; Transplantation, Homologous/adverse effects | |||||
| Chemical Substances | Creatinine (AYI8EX34EU) ; Tacrolimus (WM0HAQ4WNM) | |||||
| Language | English | |||||
| Publishing date | 2020-12-18 | |||||
| Publishing country | United States | |||||
| Document type | Case Reports ; Journal Article | |||||
| ZDB-ID | 82046-5 | |||||
| ISSN | 1873-2623 ; 0041-1345 | |||||
| ISSN (online) | 1873-2623 | |||||
| ISSN | 0041-1345 | |||||
| DOI | 10.1016/j.transproceed.2020.10.048 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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