Article ; Online: Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2): Codon Usage and Replicative Fitness.
2020 Volume 7, Issue 3, Page(s) 92–94
Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) codon usage, as shown ... coronavirus OC43 (HCoV-OC43) codon usage. Such translational advantage might facilitate SARS-CoV-2 replication ... immunogenicity, and pathogenicity, thus also accounting for the less harmful character of HCoV-OC43 infection. ...
| Abstract | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) codon usage, as shown by the polyprotein coding sequence, shows better translation potential in the human host when compared with human coronavirus OC43 (HCoV-OC43) codon usage. Such translational advantage might facilitate SARS-CoV-2 replication, immunogenicity, and pathogenicity, thus also accounting for the less harmful character of HCoV-OC43 infection. |
|---|---|
| Language | English |
| Publishing date | 2020-12-02 |
| Publishing country | Germany |
| Document type | Journal Article |
| ZDB-ID | 3009997-3 |
| ISSN | 2699-9404 ; 2699-9404 |
| ISSN (online) | 2699-9404 |
| ISSN | 2699-9404 |
| DOI | 10.1055/s-0040-1721080 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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