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  1. Article ; Online: HIV/SARS-CoV-2 coinfection: A global perspective.

    Kanwugu, Osman N / Adadi, Parise

    Journal of medical virology

    2020  Volume 93, Issue 2, Page(s) 726–732

    Abstract: ... Several cases of coinfection with HIV and SARS-CoV-2 have been reported from different parts of the globe ... CoV-2) has rapidly spread throughout the world and has become a global pandemic. Several medical ... This review seeks to provide a holistic overview of SARS-CoV-2 infection in PLWH. ...

    Abstract Since its first appearance in Wuhan, China, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread throughout the world and has become a global pandemic. Several medical comorbidities have been identified as risk factors for coronavirus disease 2019 (COVID-19). However, it remains unclear whether people living with human immunodefeciency virus (PLWH) are at an increased risk of COVID-19 and severe disease manifestation, with controversial suggestion that HIV-infected individuals could be protected from severe COVID-19 by means of antiretroviral therapy or HIV-related immunosuppression. Several cases of coinfection with HIV and SARS-CoV-2 have been reported from different parts of the globe. This review seeks to provide a holistic overview of SARS-CoV-2 infection in PLWH.
    MeSH term(s) Adult ; Anti-HIV Agents/therapeutic use ; Antiretroviral Therapy, Highly Active/statistics & numerical data ; CD4-Positive T-Lymphocytes/drug effects ; CD4-Positive T-Lymphocytes/immunology ; CD4-Positive T-Lymphocytes/virology ; COVID-19/epidemiology ; COVID-19/immunology ; COVID-19/mortality ; COVID-19/virology ; Coinfection ; Comorbidity ; Diabetes Mellitus/epidemiology ; Diabetes Mellitus/physiopathology ; Female ; HIV/drug effects ; HIV/growth & development ; HIV/pathogenicity ; HIV Infections/drug therapy ; HIV Infections/epidemiology ; HIV Infections/mortality ; HIV Infections/virology ; Humans ; Hypertension/epidemiology ; Hypertension/physiopathology ; Immunocompromised Host ; Male ; Middle Aged ; Pandemics ; SARS-CoV-2/immunology ; SARS-CoV-2/pathogenicity ; Survival Analysis ; Treatment Outcome
    Chemical Substances Anti-HIV Agents
    Keywords covid19
    Language English
    Publishing date 2020-07-28
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.26321
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: HIV/SARS-CoV-2 coinfection: A global perspective

    Kanwugu, Osman N / Adadi, Parise

    J. med. virol

    Abstract: ... Several cases of coinfection with HIV and SARS-CoV-2 have been reported from different parts of the globe ... CoV-2) has rapidly spread throughout the world and has become a global pandemic. Several medical ... This review seeks to provide a holistic overview of SARS-CoV-2 infection in PLWH. ...

    Abstract Since its first appearance in Wuhan, China, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly spread throughout the world and has become a global pandemic. Several medical comorbidities have been identified as risk factors for coronavirus disease 2019 (COVID-19). However, it remains unclear whether people living with human immunodefeciency virus (PLWH) are at an increased risk of COVID-19 and severe disease manifestation, with controversial suggestion that HIV-infected individuals could be protected from severe COVID-19 by means of antiretroviral therapy or HIV-related immunosuppression. Several cases of coinfection with HIV and SARS-CoV-2 have been reported from different parts of the globe. This review seeks to provide a holistic overview of SARS-CoV-2 infection in PLWH.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #659544
    Database COVID19

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  3. Article ; Online: HIV and SARS-Cov-2 Co-Infection: A Local Perspective.

    Bilek, Heval Can / Deveci, Aydın

    Infectious diseases & clinical microbiology

    2022  Volume 4, Issue 2, Page(s) 122–128

    Abstract: ... patients from a local perspective.: Methods: HIV and SARS-CoV-2 co-infected patients diagnosed between ... coronavirus 2 (SARS-CoV-2). We aimed to evaluate the clinical course of HIV and SARS-CoV-2 co-infected ... Thirty HIV and SARS-CoV-2 co-infected patients were included. Five patients were female, 25 were male ...

    Abstract Objective: As the Coronavirus disease 2019 (COVID-19) pandemic spread globally, more human immunodeficiency virus (HIV) positive patients began to appear infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We aimed to evaluate the clinical course of HIV and SARS-CoV-2 co-infected patients from a local perspective.
    Methods: HIV and SARS-CoV-2 co-infected patients diagnosed between March 2020 to June 2021 at a tertiary hospital in Turkey were analyzed retrospectively.
    Results: Thirty HIV and SARS-CoV-2 co-infected patients were included. Five patients were female, 25 were male, and the mean age was 44.5 ±10.2 years. Twenty-three (76.7%) patients were known to be HIV-positive before their admission to the hospital, and seven (23.7%) patients, were detected by screening after the diagnosis of COVID-19. All patients were known to be HIV-positive; they were on antiretroviral therapy (ART) and virologically suppressed. Twenty-seven patients had a mild course. Three patients were hospitalized, and of them, two patients had died. All hospitalized patients were male and were ART-naïve.
    Conclusion: HIV infection alone did not increase the severity of the course of COVID-19 and did not increase the mortality in COVID-19.
    Language English
    Publishing date 2022-06-13
    Publishing country Turkey
    Document type Journal Article
    ISSN 2667-646X
    ISSN (online) 2667-646X
    DOI 10.36519/idcm.2022.131
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: HIV/SARS‐CoV‐2 coinfection

    Kanwugu, Osman N. / Adadi, Parise

    Journal of Medical Virology ; ISSN 0146-6615 1096-9071

    A global perspective

    2020  

    Keywords Virology ; Infectious Diseases ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    DOI 10.1002/jmv.26321
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: SARS-CoV-2 and HIV-1: Should HIV-1-Infected Individuals in Sub-Saharan Africa Be Considered a Priority Group for the COVID-19 Vaccines?

    Mandala, Wilson Lewis / Liu, Michael K P

    Frontiers in immunology

    2021  Volume 12, Page(s) 797117

    Abstract: Since its emergence in 2019 SARS-CoV-2 has proven to have a higher level of morbidity and mortality ... from the devastating effect of SARS-CoV-2, at present almost every country has been affected. Although no association ... uneven particularly in Africa. The emergence of SARS-CoV-2 variants, such as Beta and Delta, which seem ...

    Abstract Since its emergence in 2019 SARS-CoV-2 has proven to have a higher level of morbidity and mortality compared to the other prevailing coronaviruses. Although initially most African countries were spared from the devastating effect of SARS-CoV-2, at present almost every country has been affected. Although no association has been established between being HIV-1-infected and being more vulnerable to contracting COVID-19, HIV-1-infected individuals have a greater risk of developing severe COVID-19 and of COVID-19 related mortality. The rapid development of the various types of COVID-19 vaccines has gone a long way in mitigating the devastating effects of the virus and has controlled its spread. However, global vaccine deployment has been uneven particularly in Africa. The emergence of SARS-CoV-2 variants, such as Beta and Delta, which seem to show some subtle resistance to the existing vaccines, suggests COVID-19 will still be a high-risk infection for years. In this review we report on the current impact of COVID-19 on HIV-1-infected individuals from an immunological perspective and attempt to make a case for prioritising COVID-19 vaccination for those living with HIV-1 in Sub-Saharan Africa (SSA) countries like Malawi as one way of minimising the impact of COVID-19 in these countries.
    MeSH term(s) Africa South of the Sahara ; CD4-Positive T-Lymphocytes/immunology ; COVID-19/mortality ; COVID-19/prevention & control ; Coinfection/prevention & control ; HIV Infections/mortality ; HIV Seropositivity ; Health Priorities ; Humans ; Mass Vaccination/methods ; SARS-CoV-2/genetics ; SARS-CoV-2/immunology
    Language English
    Publishing date 2021-11-08
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2021.797117
    Database MEDical Literature Analysis and Retrieval System OnLINE

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