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  1. Article: Red Blood cell distribution width: an emerging diagnostic factor of acute appendicitis?

    Karagöz, Ergenekon / Tanoglu, Alpaslan

    World journal of emergency surgery : WJES

    2013  Volume 8, Issue 1, Page(s) 54

    Abstract: ... even death. We read with great interest the article 'The role of red cell distribution width (RDW ... Acute appendicitis is the most common surgical abdominal emergency. Immidiate diagnosis ... in the diagnosis of acute appendicitis: a retrospective case-controlled study' by Narci et al. and wanted ...

    Abstract Acute appendicitis is the most common surgical abdominal emergency. Immidiate diagnosis of this disease is crucial, because this condition can lead to appendiceal perforation, potential peritonitis, and even death. We read with great interest the article 'The role of red cell distribution width (RDW) in the diagnosis of acute appendicitis: a retrospective case-controlled study' by Narci et al. and wanted to discuss whether RDW alone provide certain information about the inflammatory status of the patient with acute appendicitis.
    Language English
    Publishing date 2013-12-26
    Publishing country England
    Document type Journal Article
    ISSN 1749-7922
    ISSN 1749-7922
    DOI 10.1186/1749-7922-8-54
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: DIAGNOSIS OF ACUTE APPENDICITIS AND APPENDICULAR PERFORATION: EVALUATION OF PLATELET INDICES AND RED CELL DISTRIBUTION WIDTH AS EMERGING BIOMARKERS.

    Ag, Chetan / Patil, Vijaya

    Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery

    2023  Volume 36, Page(s) e1757

    Abstract: ... platelet distribution width (PDW), and red cell distribution width (RDW) in relation to the diagnosis ... to acute appendicitis, which can be a predictive factor.: Conclusions: The elevated value of MPV and PDW ... of acute appendicitis and appendicular perforation. Thus, these values can be used as diagnostic cost ...

    Abstract Background: Acute appendicitis is a common surgical emergency worldwide. Recent studies on hematological inflammatory markers concerning acute appendicitis have shown variable results.
    Aims: The aim of this study was to evaluate pre-operative values of platelet indices such as mean platelet volume (MPV) and platelet distribution width (PDW), and red cell distribution width (RDW) in relation to the diagnosis of acute appendicitis and their efficacy as predictors of appendicular perforation.
    Methods: A prospective observational study of 190 patients diagnosed with appendicitis and who underwent an appendectomy was undertaken and confirmed histopathologically. Preoperatively, blood samples of white blood cells (WBCs), platelet count, MPV, PDW, and RDW were analyzed using a Sysmex XN1000 analyzer machine.
    Results: Of 190 patients, 169 had acute appendicitis, and 21 had perforated appendicitis. The mean age of patients was 28.04 ± 14.2 years. The male-to-female ratio was 1.5:1. The WBC (p<0.05), MPV (p<0.05), and PDW (p<0.05) were found to have higher statistically significant values in acute appendicitis and perforated appendicitis compared to the RDW (p>0.05). However, perforated appendicitis had a higher RDW value compared to acute appendicitis, which can be a predictive factor.
    Conclusions: The elevated value of MPV and PDW associated with leukocytosis can be used as supportive evidence for the clinical and radiological diagnosis of acute appendicitis and appendicular perforation. Thus, these values can be used as diagnostic cost-effective inflammatory biomarkers.
    MeSH term(s) Humans ; Female ; Male ; Adolescent ; Young Adult ; Adult ; Appendicitis/diagnosis ; Appendicitis/surgery ; Erythrocyte Indices ; Appendectomy ; Acute Disease ; Biomarkers
    Chemical Substances Biomarkers
    Language English
    Publishing date 2023-09-15
    Publishing country Brazil
    Document type Observational Study ; Journal Article
    ISSN 2317-6326
    ISSN (online) 2317-6326
    DOI 10.1590/0102-672020230039e1757
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

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