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Article ; Online: Reply: COVID-19 and Pulmonary Embolism: Diagnostic Imaging Trends.

Zuckier, Lionel S / Moadel, Renée M / Haramati, Linda B / Freeman, Leonard

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

2020 Volume 61, Issue 8, Page(s) 1102–1103

MeSH term(s)	Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Diagnostic Imaging ; Humans ; Pandemics ; Pneumonia, Viral ; Pulmonary Embolism ; SARS-CoV-2
Keywords	covid19
Language	English
Publishing date	2020-06-23
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	80272-4
ISSN	1535-5667 ; 0097-9058 ; 0161-5505 ; 0022-3123
ISSN (online)	1535-5667
ISSN	0097-9058 ; 0161-5505 ; 0022-3123
DOI	10.2967/jnumed.120.250530
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Zs.A 114: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: COVID-19 and Pulmonary Embolism: Diagnostic Imaging Trends.

Karimzadeh, Sedighe / Raut, Akshay / Huy, Nguyen Tien

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

2020 Volume 61, Issue 8, Page(s) 1102

MeSH term(s)	Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Diagnostic Imaging ; Humans ; Pandemics ; Pneumonia, Viral ; Pulmonary Embolism ; SARS-CoV-2
Keywords	covid19
Language	English
Publishing date	2020-05-22
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	80272-4
ISSN	1535-5667 ; 0097-9058 ; 0161-5505 ; 0022-3123
ISSN (online)	1535-5667
ISSN	0097-9058 ; 0161-5505 ; 0022-3123
DOI	10.2967/jnumed.120.248518
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 114: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 328: Show issues

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Article: COVID-19 and Pulmonary Embolism: Diagnostic Imaging Trends

Karimzadeh, Sedighe / Raut, Akshay / Huy, Nguyen Tien

J Nucl Med

Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #343592
Database	COVID19

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Article: Reply: COVID-19 and Pulmonary Embolism: Diagnostic Imaging Trends

Zuckier, Lionel S / Moadel, Renée M / Haramati, Linda B / Freeman, Leonard

J Nucl Med

Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #711419
Database	COVID19

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Article: COVID-19 and Pulmonary Embolism: Diagnostic Imaging Trends /Reply: COVID-19 and Pulmonary Embolism: Diagnostic Imaging Trends

Karimzadeh, Sedighe / Raut, Akshay / Huy, Nguyen Tien / Zuckier, Lionel S. / Moadel, Renée M. / Haramati, Linda B. / Freeman, Leonard

Journal of Nuclear Medicine

Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #826912
Database	COVID19

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Article ; Online: CT pulmonary angiography in the emergency department: utilization and positivity rates during various phases of the COVID-19 pandemic.

Mugu, Vamshi K / Carr, Brendan M / Olson, Michael C / Khandelwal, Ashish

Emergency radiology

2024 Volume 31, Issue 3, Page(s) 293–301

Abstract: Purpose: To evaluate the trends in utilization and results of computed tomography pulmonary ... the end of COVID-19 public health emergency by the WHO and the United States HHS with respect to CTPA ... angiography (CTPA study) for detection of acute pulmonary embolism (PE) in the Emergency Department (ED ...

Abstract	Purpose: To evaluate the trends in utilization and results of computed tomography pulmonary angiography (CTPA study) for detection of acute pulmonary embolism (PE) in the Emergency Department (ED) during different phases of COVID-19 public health emergency. Methods: We conducted a retrospective review of CTPA studies ordered through our ED in the months of March through May during five consecutive years from 2019 to 2023, designated as pre-pandemic, early, ongoing, recovery, and post-pandemic periods respectively. Collected characteristics included patient age, patient sex, and result of the study. Results: The utilization of CTPA studies for ED patients increased during the early, ongoing, and recovery periods. CTPA study utilization in the post-pandemic period was not significantly different from the pre-pandemic period (p = 0.08). No significant difference in CTPA study utilization was noted in the other periods when stratified by age group or sex, compared to the pre-pandemic period. The positivity rate of acute PE in ED patients was not significantly different in other periods compared to the pre-pandemic period. Conclusion: At our institution, the utilization and positivity rates of CTPA studies for the ED patients were not significantly different in the post-pandemic period compared to the pre-pandemic period. While studies spanning a larger timeframe and involving multiple institutions are needed to test the applicability of this observation to a wider patient population beyond our defined post-pandemic period, we conclude that our study provides some confidence to the ordering provider and the radiologist in embracing the end of COVID-19 public health emergency by the WHO and the United States HHS with respect to CTPA studies.
MeSH term(s)	Humans ; COVID-19/epidemiology ; COVID-19/diagnostic imaging ; Male ; Emergency Service, Hospital/statistics & numerical data ; Female ; Pulmonary Embolism/diagnostic imaging ; Retrospective Studies ; Computed Tomography Angiography/statistics & numerical data ; Middle Aged ; SARS-CoV-2 ; Aged ; Adult ; Pandemics ; Aged, 80 and over
Language	English
Publishing date	2024-03-23
Publishing country	United States
Document type	Journal Article
ZDB-ID	1425144-9
ISSN	1438-1435 ; 1070-3004
ISSN (online)	1438-1435
ISSN	1070-3004
DOI	10.1007/s10140-024-02218-0
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 4880: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Pulmonary circulation abnormalities in post-acute COVID-19 syndrome: dual-energy CT angiographic findings in 79 patients.

Mohamed, Islam / de Broucker, Virginie / Duhamel, Alain / Giordano, Jessica / Ego, Alice / Fonne, Nicolas / Chenivesse, Cécile / Remy, Jacques / Remy-Jardin, Martine

European radiology

2023 Volume 33, Issue 7, Page(s) 4700–4712

Abstract: ... HRCT and spectral imaging for proper understanding of post COVID-19 lung sequelae. ... of the disease, acute pulmonary embolism and alterations at the level of lung microcirculation can be identified ... 79; 5%) PE; and (b) residual post COVID-19 lung infiltration (67/79; 85%). Lung perfusion was ...

Abstract	Objectives: To evaluate the frequency and pattern of pulmonary vascular abnormalities in the year following COVID-19. Methods: The study population included 79 patients remaining symptomatic more than 6 months after hospitalization for SARS-CoV-2 pneumonia who had been evaluated with dual-energy CT angiography. Results: Morphologic images showed CT features of (a) acute (2/79; 2.5%) and focal chronic (4/79; 5%) PE; and (b) residual post COVID-19 lung infiltration (67/79; 85%). Lung perfusion was abnormal in 69 patients (87.4%). Perfusion abnormalities included (a) perfusion defects of 3 types: patchy defects (n = 60; 76%); areas of non-systematized hypoperfusion (n = 27; 34.2%); and/or PE-type defects (n = 14; 17.7%) seen with (2/14) and without (12/14) endoluminal filling defects; and (b) areas of increased perfusion in 59 patients (74.9%), superimposed on ground-glass opacities (58/59) and vascular tree-in-bud (5/59). PFTs were available in 10 patients with normal perfusion and in 55 patients with abnormal perfusion. The mean values of functional variables did not differ between the two subgroups with a trend toward lower DLCO in patients with abnormal perfusion (74.8 ± 16.7% vs 85.0 ± 8.1). Conclusion: Delayed follow-up showed CT features of acute and chronic PE but also two types of perfusion abnormalities suggestive of persistent hypercoagulability as well as unresolved/sequelae of microangiopathy. Clinical relevance statement: Despite dramatic resolution of lung abnormalities seen during the acute phase of the disease, acute pulmonary embolism and alterations at the level of lung microcirculation can be identified in patients remaining symptomatic in the year following COVID-19. Key points: • This study demonstrates newly developed proximal acute PE/thrombosis in the year following SARS-CoV-2 pneumonia. • Dual-energy CT lung perfusion identified perfusion defects and areas of increased iodine uptake abnormalities, suggestive of unresolved damage to lung microcirculation. • This study suggests a complementarity between HRCT and spectral imaging for proper understanding of post COVID-19 lung sequelae.
MeSH term(s)	Humans ; Computed Tomography Angiography ; Pulmonary Circulation ; Post-Acute COVID-19 Syndrome ; COVID-19 ; SARS-CoV-2 ; Tomography, X-Ray Computed/methods ; Lung/diagnostic imaging ; Lung/blood supply ; Pulmonary Embolism/diagnostic imaging ; Vascular Diseases
Language	English
Publishing date	2023-04-25
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1085366-2
ISSN	1432-1084 ; 0938-7994 ; 1613-3749
ISSN (online)	1432-1084
ISSN	0938-7994 ; 1613-3749
DOI	10.1007/s00330-023-09618-9
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Zs.A 3300: Show issues

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Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

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Article ; Online: Role of multimodality imaging in evaluation of cardiovascular involvement in COVID-19.

Citro, Rodolfo / Pontone, Gianluca / Bellino, Michele / Silverio, Angelo / Iuliano, Giuseppe / Baggiano, Andrea / Manka, Robert / Iesu, Severino / Vecchione, Carmine / Asch, Federico Miguel / Ghadri, Jelena Rima / Templin, Christian

Trends in cardiovascular medicine

2020 Volume 31, Issue 1, Page(s) 8–16

Abstract: ... to perform serial invasive and non-invasive diagnostic testing in COVID-19 patients and high serum troponin ... takotsubo syndrome and pulmonary embolism. ... Due to its mobility and bedside feasibility, echocardiography is the first-line imaging technique ...

Abstract	The management of patients infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may be difficult due to the need for dedicated in-hospital pathways, protective measures for healthcare professionals and isolated beds of intensive care, particularly in areas overwhelmed by wide viral spread. Although pneumonia is the most common clinical manifestation in coronavirus disease 2019 (COVID-19), a variety of cardiovascular complications have been reported. An integrated diagnostic algorithm in SARS-CoV-2-infected patients with suspected cardiac involvement (laboratory findings of myocardial injury and electrocardiographic changes) may help to avoid unnecessary examinations and minimize the risk of operator infection. Due to its mobility and bedside feasibility, echocardiography is the first-line imaging technique in this clinical setting. It quickly provides information on ventricular functions, pulmonary hypertension, valve disease and pericardial effusion. In case of ST-segment elevation (STE), urgent coronary angiography should be performed. Cardiac ultrasound helps distinguish between ischemic and non-ischemic myocardial disease and may detect pericardial disease. Transmural ischemic electrocardiographic changes, with or without early elevated troponin levels or echocardiographic wall motion abnormalities, will determine the need for early invasive coronary angiography. Computed tomography (CT) through its multiple applications (chest CT; CT pulmonary angiography and coronary CT angiography; late iodine enhancement CT) and cardiac magnetic resonance might be helpful in reinforcing or redirecting diagnostic hypothesis emerged by other clinical, electrocardiographic and echocardiographic findings. The current pandemic makes it challenging to perform serial invasive and non-invasive diagnostic testing in COVID-19 patients and high serum troponin level. Nevertheless, thoughtful and systematic use of an appropriate multimodality imaging strategy is clinically relevant to detect cardiac injury and distinguish myocardial infarction from, myocarditis, takotsubo syndrome and pulmonary embolism.
MeSH term(s)	COVID-19/complications ; COVID-19/diagnostic imaging ; Cardiac Imaging Techniques ; Cardiovascular Diseases/diagnostic imaging ; Cardiovascular Diseases/virology ; Humans ; Magnetic Resonance Imaging ; Multimodal Imaging ; Tomography, X-Ray Computed
Keywords	covid19
Language	English
Publishing date	2020-10-13
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1097434-9
ISSN	1873-2615 ; 1050-1738
ISSN (online)	1873-2615
ISSN	1050-1738
DOI	10.1016/j.tcm.2020.10.001
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Zs.A 3419: Show issues

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Article ; Online: Association between pulmonary embolism and COVID-19 severe pneumonia: Experience from two centers in the core of the infection Italian peak.

Valle, C / Bonaffini, P A / Dal Corso, M / Mercanzin, E / Franco, P N / Sonzogni, A / Vacca, G / Gianatti, A / Sironi, S

European journal of radiology

2021 Volume 137, Page(s) 109613

Abstract: Purpose: Pulmonary embolism (PE) in COVID-19 patients can play a key role in precipitating ... association with D-dimer (DD), pulmonary stage of disease and prognosis.: Method: COVID-19 patients of two ... revealed PE in 65 patients (57 %), with concomitant pulmonary trunk and/or main arteries involvement in 16 ...

Abstract	Purpose: Pulmonary embolism (PE) in COVID-19 patients can play a key role in precipitating clinical conditions. We aimed to evaluate PE distribution on CTA and to investigate any possible association with D-dimer (DD), pulmonary stage of disease and prognosis. Method: COVID-19 patients of two affiliated Hospitals, undergone a CTA examination for PE suspicion, were retrospectively enrolled. Comorbidities, laboratory tests and clinical outcomes (hospitalization, discharge, death) were assessed. A parenchymal stage (early, progressive, peak, absorption) for lung involvement was assigned. Results: A cohort of 114 patients (mean age 61 years; 26.3 % females) with severe COVID-19 pneumonia were evaluated. At last follow-up 25 (21.9 %) were hospitalized, 72 (63.2 %) discharged, 17 (14.9 %) dead. Eighty-eight patients (77.2 %) had at least one comorbidity, being cardiovascular ones the most frequent (44.7 %). CTA revealed PE in 65 patients (57 %), with concomitant pulmonary trunk and/or main arteries involvement in 16.9 %. PE defects were ubiquitous in 18.5 % of cases. The predominant parenchymal stages were the progressive (24.6 %) and peak (67.7 %). DD levels showed a significant correlation with PE occurrence and extent in pulmonary branches, despite anticoagulant therapies; trend of correlation with pulmonary stages was also noted. Conclusions: PE is a frequent complication in severe COVID-19 patients, particularly during central parenchymal stages and despite ongoing anticoagulant therapy. CTA and DD levels play a crucial role in the assessment of suspected PE, despite anticoagulant therapies, along with proper information about lung involvement extent.
MeSH term(s)	COVID-19 ; Female ; Humans ; Italy/epidemiology ; Male ; Middle Aged ; Pulmonary Embolism/diagnostic imaging ; Pulmonary Embolism/epidemiology ; Retrospective Studies ; SARS-CoV-2
Language	English
Publishing date	2021-02-24
Publishing country	Ireland
Document type	Journal Article
ZDB-ID	138815-0
ISSN	1872-7727 ; 0720-048X
ISSN (online)	1872-7727
ISSN	0720-048X
DOI	10.1016/j.ejrad.2021.109613
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Article: Role of multimodality imaging in evaluation of cardiovascular involvement in COVID-19

Trends cardiovasc. med

Abstract	The management of patients infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may be difficult due to the need for dedicated in-hospital pathways, protective measures for healthcare professionals and isolated beds of intensive care, particularly in areas overwhelmed by wide viral spread. Although pneumonia is the most common clinical manifestation in coronavirus disease 2019 (COVID-19), a variety of cardiovascular complications have been reported. An integrated diagnostic algorithm in SARS-CoV-2-infected patients with suspected cardiac involvement (laboratory findings of myocardial injury and electrocardiographic changes) may help to avoid unnecessary examinations and minimize the risk of operator infection. Due to its mobility and bedside feasibility, echocardiography is the first-line imaging technique in this clinical setting. It quickly provides information on ventricular functions, pulmonary hypertension, valve disease and pericardial effusion. In case of ST-segment elevation (STE), urgent coronary angiography should be performed. Cardiac ultrasound helps distinguish between ischemic and non-ischemic myocardial disease and may detect pericardial disease. Transmural ischemic electrocardiographic changes, with or without early elevated troponin levels or echocardiographic wall motion abnormalities, will determine the need for early invasive coronary angiography. Computed tomography (CT) through its multiple applications (chest CT; CT pulmonary angiography and coronary CT angiography; late iodine enhancement CT) and cardiac magnetic resonance might be helpful in reinforcing or redirecting diagnostic hypothesis emerged by other clinical, electrocardiographic and echocardiographic findings. The current pandemic makes it challenging to perform serial invasive and non-invasive diagnostic testing in COVID-19 patients and high serum troponin level. Nevertheless, thoughtful and systematic use of an appropriate multimodality imaging strategy is clinically relevant to detect cardiac injury and distinguish myocardial infarction from, myocarditis, takotsubo syndrome and pulmonary embolism.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #857199
Database	COVID19

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