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Article: Pathogen detection with electrochemical biosensors: Advantages, challenges and future perspectives.

Kaya, Hüseyin Oğuzhan / Cetin, Arif E / Azimzadeh, Mostafa / Topkaya, Seda Nur

Journal of electroanalytical chemistry (Lausanne, Switzerland)

2021  Volume 882, Page(s) 114989

Abstract: ... techniques, detection principles, and applications of various pathogens with the electrochemical biosensors ... Detection of pathogens, e.g., bacteria and viruses, is still a big challenge in analytical medicine ... viruses using electrochemical biosensors. Moreover, electrochemical biosensors for pathogen detection were ...

Abstract Detection of pathogens, e.g., bacteria and viruses, is still a big challenge in analytical medicine due to their vast number and variety. Developing strategies for rapid, inexpensive, specific, and sensitive detection of the pathogens using nanomaterials, integrating with microfluidics devices, amplification methods, or even combining these strategies have received significant attention. Especially, after the health-threatening COVID-19 outbreak, rapid and sensitive detection of pathogens became very critical. Detection of pathogens could be realized with electrochemical, optical, mass sensitive, or thermal methods. Among them, electrochemical methods are very promising by bringing different advantages, i.e., they exhibit more versatile detection schemes and real-time quantification as well as label-free measurements, which provides a broader application perspective. In this review, we discuss the recent advances for the detection of bacteria and viruses using electrochemical biosensors. Moreover, electrochemical biosensors for pathogen detection were broadly reviewed in terms of analyte, bio-recognition and transduction elements. Different fabrication techniques, detection principles, and applications of various pathogens with the electrochemical biosensors were also discussed.
Language English
Publishing date 2021-01-09
Publishing country Switzerland
Document type Journal Article ; Review
ZDB-ID 1491150-4
ISSN 1873-2569 ; 1572-6657 ; 0368-1874 ; 0022-0728
ISSN (online) 1873-2569
ISSN 1572-6657 ; 0368-1874 ; 0022-0728
DOI 10.1016/j.jelechem.2021.114989
Database MEDical Literature Analysis and Retrieval System OnLINE

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