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  1. Article ; Online: COVID-19 and ST elevations-keep an open mind: a case report.

    Kendall, Michael R / Reddy, Sridhar M / Meinke, Laura E / Acharya, Deepak

    European heart journal. Case reports

    2020  Volume 4, Issue 6, Page(s) 1–4

    Abstract: ... with tenecteplase 50 mg i.v. with complete resolution of her ST elevations and improved oxygenation.: Discussion ... hypoxic and hypotensive. Telemetry was noted to have ST changes, prompting ECG that revealed ... anterior ST elevations that mimic myocardial infarction have previously been described. This phenomenon is ...

    Abstract Background: Coronavirus disease 2019 (COVID-19) has been associated with a range of cardiovascular manifestations, including myocardial injury and thrombo-embolism. Pulmonary embolism (PE) causing anteroseptal/anterior ST elevations that mimic myocardial infarction have previously been described. This phenomenon is thought to be related to right ventricular injury from large emboli.
    Case summary: A 48-year-old woman with history of type 2 diabetes mellitus and hypertension presented to her local hospital with fever, cough, nausea, and dyspnoea. A test for SARS-CoV-2 was taken, and she was discharged with instructions to self-quarantine. She was subsequently notified of a positive SARS-CoV-2 result. Three days later, she re-presented with worsening dyspnoea and respiratory failure requiring intubation. On hospital Day 6, she became acutely hypoxic and hypotensive. Telemetry was noted to have ST changes, prompting ECG that revealed sinus tachycardia with prominent new ST elevations in her precordial leads. Transthoracic echocardiogram showed normal left ventricular function; however, the right ventricle was moderately dilated with positive McConnell's sign. Due to her unstable clinical state and high suspicion for PE, she was treated with tenecteplase 50 mg i.v. with complete resolution of her ST elevations and improved oxygenation.
    Discussion: Given the high rates of thrombo-embolic events in COVID-19 patients, PE should be in the differential diagnosis of ST elevation, particularly in younger patients with few risk factors for coronary artery disease.
    Language English
    Publishing date 2020-10-19
    Publishing country England
    Document type Journal Article
    ISSN 2514-2119
    ISSN (online) 2514-2119
    DOI 10.1093/ehjcr/ytaa269
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: COVID-19 and ST elevationskeep an open mind

    Kendall, Michael R / Reddy, Sridhar M / Meinke, Laura E / Acharya*, Deepak

    European Heart Journal - Case Reports ; ISSN 2514-2119

    a case report

    2020  

    Abstract: ... for PE, she was treated with tenecteplase 50 mg i.v. with complete resolution of her ST elevations and ... On hospital Day 6, she became acutely hypoxic and hypotensive. Telemetry was noted to have ST changes ... anteroseptal/anterior ST elevations that mimic myocardial infarction have previously been described ...

    Abstract Abstract Background Coronavirus disease 2019 (COVID-19) has been associated with a range of cardiovascular manifestations, including myocardial injury and thrombo-embolism. Pulmonary embolism (PE) causing anteroseptal/anterior ST elevations that mimic myocardial infarction have previously been described. This phenomenon is thought to be related to right ventricular injury from large emboli. Case summary A 48-year-old woman with history of type 2 diabetes mellitus and hypertension presented to her local hospital with fever, cough, nausea, and dyspnoea. A test for SARS-CoV-2 was taken, and she was discharged with instructions to self-quarantine. She was subsequently notified of a positive SARS-CoV-2 result. Three days later, she re-presented with worsening dyspnoea and respiratory failure requiring intubation. On hospital Day 6, she became acutely hypoxic and hypotensive. Telemetry was noted to have ST changes, prompting ECG that revealed sinus tachycardia with prominent new ST elevations in her precordial leads. Transthoracic echocardiogram showed normal left ventricular function; however, the right ventricle was moderately dilated with positive McConnell’s sign. Due to her unstable clinical state and high suspicion for PE, she was treated with tenecteplase 50 mg i.v. with complete resolution of her ST elevations and improved oxygenation. Discussion Given the high rates of thrombo-embolic events in COVID-19 patients, PE should be in the differential diagnosis of ST elevation, particularly in younger patients with few risk factors for coronary artery disease.
    Keywords covid19
    Language English
    Publisher Oxford University Press (OUP)
    Publishing country uk
    Document type Article ; Online
    DOI 10.1093/ehjcr/ytaa269
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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