Article: Profiling Laboratory Biomarkers Associated with COVID-19 Disease Progression: A Single-Center Experience.
International journal of microbiology
2021 Volume 2021, Page(s) 6643333
Abstract: ... markers in different categories of COVID-19 in admitted patients.: Methods: In a single-center ... observational study of 50 in-hospital patients who were diagnosed with COVID-19 and admitted ... and ferritin are markedly increased in COVID-19 patients. Increased CRP and ferritin levels were also ...
| Abstract | Background: There is clinical importance to investigate the disease progression through potential biomarkers of SARS-CoV-2 infection. In the present study, we aim to evaluate the significance of inflammatory markers in different categories of COVID-19 in admitted patients. Methods: In a single-center, observational study of 50 in-hospital patients who were diagnosed with COVID-19 and admitted to the intensive care unit of a tertiary care hospital in Peshawar, infection biomarkers, including hs-CRP, serum ferritin, serum creatinine, ALT, ALP, cardiac troponin-I, and IL-6 were analyzed. Results: The median age was 61.3 years. 70% (35) were male while 30% (15) were female. We noted significantly increased hs-CRP (9.32 mg/dL ± 10.03) and ferritin levels (982.3 ng/ml ± 601.9). A noteworthy increase was observed in neutrophil count (11.05 × 10 Conclusion: The serum levels of CRP, troponin-I, ALP, ALT, serum creatinine, and ferritin are markedly increased in COVID-19 patients. Increased CRP and ferritin levels were also associated with secondary bacterial infection and poor clinical outcomes. |
|---|---|
| Language | English |
| Publishing date | 2021-02-09 |
| Publishing country | Egypt |
| Document type | Journal Article |
| ZDB-ID | 2467270-1 |
| ISSN | 1687-9198 ; 1687-918X |
| ISSN (online) | 1687-9198 |
| ISSN | 1687-918X |
| DOI | 10.1155/2021/6643333 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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