Article ; Online: Ribosome Display Technology: Applications in Disease Diagnosis and Control.
Antibodies (Basel, Switzerland)
2020 Volume 9, Issue 3
Abstract: ... technology in biomedical and agricultural fields in the generation of recombinant scFvs for disease diagnostics and control. ... of this technology as one of the foremost antibody production methods. Ribosome display has become a vital tool ... Antibody ribosome display remains one of the most successful in vitro selection technologies ...
| Abstract | Antibody ribosome display remains one of the most successful in vitro selection technologies for antibodies fifteen years after it was developed. The unique possibility of direct generation of whole proteins, particularly single-chain antibody fragments (scFvs), has facilitated the establishment of this technology as one of the foremost antibody production methods. Ribosome display has become a vital tool for efficient and low-cost production of antibodies for diagnostics due to its advantageous ability to screen large libraries and generate binders of high affinity. The remarkable flexibility of this method enables its applicability to various platforms. This review focuses on the applications of ribosome display technology in biomedical and agricultural fields in the generation of recombinant scFvs for disease diagnostics and control. |
|---|---|
| Keywords | covid19 |
| Language | English |
| Publishing date | 2020-06-27 |
| Publishing country | Switzerland |
| Document type | Journal Article ; Review |
| ISSN | 2073-4468 |
| ISSN (online) | 2073-4468 |
| DOI | 10.3390/antib9030028 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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