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  1. Article ; Online: SARS-CoV-2-related chilblains.

    Ladha, Malika A / Dupuis, Elaine C

    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

    2020  Volume 192, Issue 28, Page(s) E804

    MeSH term(s) Administration, Topical ; Adolescent ; Adrenal Cortex Hormones ; Betacoronavirus/pathogenicity ; COVID-19 ; Chilblains/pathology ; Chilblains/virology ; Coronavirus Infections/immunology ; Coronavirus Infections/pathology ; Coronavirus Infections/virology ; Enzyme-Linked Immunosorbent Assay ; Female ; Fingers/blood supply ; Fingers/virology ; Humans ; Pandemics ; Patient Education as Topic ; Pneumonia, Viral/immunology ; Pneumonia, Viral/pathology ; Pneumonia, Viral/virology ; Quarantine ; SARS-CoV-2 ; Toes/blood supply ; Toes/virology
    Chemical Substances Adrenal Cortex Hormones
    Keywords covid19
    Language English
    Publishing date 2020-07-13
    Publishing country Canada
    Document type Case Reports ; Journal Article
    ZDB-ID 215506-0
    ISSN 1488-2329 ; 0008-4409 ; 0820-3946
    ISSN (online) 1488-2329
    ISSN 0008-4409 ; 0820-3946
    DOI 10.1503/cmaj.201348
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Pandemic chilblains: Are they SARS-CoV-2-related or not?

    De Greef, Axel / Coulie, Pierre G / Baeck, Marie

    Clinical immunology (Orlando, Fla.)

    2022  Volume 237, Page(s) 108984

    Abstract: ... pandemic is still unclear. Initially, SARS-CoV-2 appeared as the obvious causing agent, but two years ... detectable virus, no anti-SARS-CoV-2 antibodies and no symptoms of COVID-19. Analyses of skin biopsies ... SARS-CoV-2 would cause the lesions before being promptly eliminated by unusually strong type ...

    Abstract The exact etiopathology of chilblains observed during the Coronavirus Disease 2019 (COVID-19) pandemic is still unclear. Initially, SARS-CoV-2 appeared as the obvious causing agent, but two years of various investigations have failed to convincingly support its direct implication. Most affected individuals have no detectable virus, no anti-SARS-CoV-2 antibodies and no symptoms of COVID-19. Analyses of skin biopsies similarly failed to unambiguously demonstrate presence of the virus or its genome. In a recent hypothesis, SARS-CoV-2 would cause the lesions before being promptly eliminated by unusually strong type I interferon responses. With others, we feel that environmental factors have not been sufficiently considered, in particular cold exposure related to unprecedented containment measures. The cause of pandemic chilblains remains a stimulating puzzle which warrants further investigation.
    MeSH term(s) COVID-19 ; Chilblains/diagnosis ; Chilblains/epidemiology ; Chilblains/pathology ; Humans ; Pandemics ; SARS-CoV-2 ; Skin/pathology
    Language English
    Publishing date 2022-03-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1459903-x
    ISSN 1521-7035 ; 1521-6616
    ISSN (online) 1521-7035
    ISSN 1521-6616
    DOI 10.1016/j.clim.2022.108984
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: BNT162b2 mRNA COVID-19 vaccine-induced chilblain-like lesions reinforces the hypothesis of their relationship with SARS-CoV-2.

    Piccolo, V / Bassi, A / Argenziano, G / Mazzatenta, C / Cutrone, M / Neri, I / Grimalt, R / Russo, T

    Journal of the European Academy of Dermatology and Venereology : JEADV

    2021  Volume 35, Issue 8, Page(s) e493–e494

    MeSH term(s) BNT162 Vaccine ; COVID-19 ; COVID-19 Vaccines ; Chilblains ; Humans ; RNA, Messenger ; SARS-CoV-2
    Chemical Substances COVID-19 Vaccines ; RNA, Messenger ; BNT162 Vaccine (N38TVC63NU)
    Language English
    Publishing date 2021-05-10
    Publishing country England
    Document type Letter
    ZDB-ID 1128828-0
    ISSN 1468-3083 ; 0926-9959
    ISSN (online) 1468-3083
    ISSN 0926-9959
    DOI 10.1111/jdv.17320
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Recent outbreak of chilblain-like lesions is not directly related to SARS-CoV-2 infection.

    Rouanet, J / Lang, E / Beltzung, F / Evrard, B / Henquell, C / Joulie, I / D'Incan, M

    Journal of the European Academy of Dermatology and Venereology : JEADV

    2020  Volume 34, Issue 11, Page(s) e689–e692

    MeSH term(s) Adolescent ; Adult ; COVID-19/epidemiology ; Chilblains/epidemiology ; Child ; Disease Outbreaks ; Female ; Humans ; Male ; Middle Aged ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-07-28
    Publishing country England
    Document type Letter
    ZDB-ID 1128828-0
    ISSN 1468-3083 ; 0926-9959
    ISSN (online) 1468-3083
    ISSN 0926-9959
    DOI 10.1111/jdv.16776
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Do we have serological evidences that chilblain-like lesions are related to SARS-CoV-2? A review of the literature.

    Balestri, Riccardo / Magnano, Michela / Rizzoli, Laura / Rech, Giulia

    Dermatologic therapy

    2020  Volume 33, Issue 6, Page(s) e14229

    Abstract: ... although it is still uncertain whether CLL are related to SARS-CoV-2 infection, patients affected by CLL seem not ... of great concern. SARS-CoV-2 was initially hypothesized as the etiologic agent of CLL ... CoV-2 antibodies. Many papers were published contemporarily on this topic, reporting limited case ...

    Abstract The outbreak of chilblain-like lesions (CLL) coincidentally to the COVID-19 pandemic is a topic of great concern. SARS-CoV-2 was initially hypothesized as the etiologic agent of CLL, but, since nasopharyngeal swabs seldom resulted positive, dermatologists' attention focused on the search for specific SARS-CoV-2 antibodies. Many papers were published contemporarily on this topic, reporting limited case series. We reviewed the English literature up to the first July 2020 and, excluding single case reports, we considered 13 studies that serologically investigated 220 patients. The presence of specific antibodies was detected in 18 subjects (8.2%): isolated IgA were found in 6 patients, IgA and IgG in 1, isolated IgG in 5, and IgM in 2. In 4 patients, isotypes were not specified. Our review demonstrated a high prevalence of negative serological results in CLL: antibodies were observed only in a few patients, that are even less excluding those with positive IgA, not clearly involved in the pathogenesis of the disease. In conclusion, although it is still uncertain whether CLL are related to SARS-CoV-2 infection, patients affected by CLL seem not to be prone to shedding the virus, hence, if they are asymptomatic, we can reassure them, thus avoiding hospital referral.
    MeSH term(s) Antibodies/blood ; Antibodies, Viral/blood ; Biomarkers/blood ; COVID-19/diagnosis ; COVID-19/epidemiology ; COVID-19/immunology ; COVID-19/virology ; COVID-19 Serological Testing ; Chilblains/diagnosis ; Chilblains/epidemiology ; Chilblains/immunology ; Chilblains/virology ; Host-Pathogen Interactions ; Humans ; Predictive Value of Tests ; Risk Assessment ; Risk Factors ; SARS-CoV-2/immunology ; SARS-CoV-2/pathogenicity ; Seroepidemiologic Studies
    Chemical Substances Antibodies ; Antibodies, Viral ; Biomarkers
    Keywords covid19
    Language English
    Publishing date 2020-09-14
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1354801-3
    ISSN 1529-8019 ; 1396-0296
    ISSN (online) 1529-8019
    ISSN 1396-0296
    DOI 10.1111/dth.14229
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Recent outbreak of chilblain-like lesions is not directly related with SARS-CoV-2 infection

    Rouanet, J / Lang, E / Beltzung, F / Evrard, B / Henquell, C / Joulie, I / D039, / Incan, M

    J. Eur. Acad. Dermatol. Venereol

    Abstract: ... to the COVID-19 epidemic, suggesting a relationship between their onset and SARS-CoV-2 infection. Here ... of SARS-CoV-2 infection. ... Throughout March and April 2020, dermatologists have observed an outbreak of chilblains despite ...

    Abstract Throughout March and April 2020, dermatologists have observed an outbreak of chilblains despite climatic conditions not conducive to their apparition. These lesions have occurred simultaneously to the COVID-19 epidemic, suggesting a relationship between their onset and SARS-CoV-2 infection. Here we describe a series of 10 patients presenting chilblain-like lesions in whom we have searched for evidence of SARS-CoV-2 infection.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #32589294
    Database COVID19

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  7. Article: Recent outbreak of chilblain-like lesions is not directly related to SARS-CoV-2 infection

    Rouanet, J / Lang, E / Beltzung, F / Evrard, B / Henquell, C / Joulie, I / D039, / Incan, M

    J. Eur. Acad. Dermatol. Venereol

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #616062
    Database COVID19

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  8. Article ; Online: Do we have serological evidences that chilblain‐like lesions are related to SARSCoV2? A review of the literature

    Balestri, Riccardo / Magnano, Michela / Rizzoli, Laura / Rech, Giulia

    Dermatologic Therapy ; ISSN 1396-0296 1529-8019

    2020  

    Keywords Dermatology ; General Medicine ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    DOI 10.1111/dth.14229
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Recent outbreak of chilblain‐like lesions is not directly related to SARSCoV2 infection

    Rouanet, J. / Lang, E. / Beltzung, F. / Evrard, B. / Henquell, C. / Joulie, I. / D'Incan, M.

    Journal of the European Academy of Dermatology and Venereology ; ISSN 0926-9959 1468-3083

    2020  

    Keywords Infectious Diseases ; Dermatology ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    DOI 10.1111/jdv.16776
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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