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Article ; Online: Experiences and Short-Term Outcomes of Kidney Transplantation During the Coronavirus Disease 2019 Pandemic From a Medium-Volume Transplantation and Superregional Coronavirus Disease 2019 Treatment Center.

Laessle, Claudia / Schneider, Johanna / Pisarski, Przemyslaw / Fichtner-Feigl, Stefan / Jänigen, Bernd

Transplantation proceedings

2021  Volume 53, Issue 4, Page(s) 1146–1153

Abstract: ... In this study, we evaluated the short-term outcomes of our patients receiving a kidney transplant during ... after kidney transplantation during the first phase of the coronavirus pandemic were comparable to pre ... before the coronavirus pandemic.: Materials and methods: Our retrospective study includes 34 kidney transplant ...

Abstract Introduction: The coronavirus, which first appeared in 2019, developed into a pandemic during 2020. It remains unclear to what extent the pandemic endangers the safety of kidney transplantation programs. In this study, we evaluated the short-term outcomes of our patients receiving a kidney transplant during the first phase and compared them with patients who received a kidney transplant immediately before the coronavirus pandemic.
Materials and methods: Our retrospective study includes 34 kidney transplant recipients between October 1, 2019, and April 30, 2020. Nineteen patients from the phase immediately prior to the first coronavirus wave (pre-corona group), and 15 patients from the phase of the first coronavirus wave (corona group) were studied. We retrospectively evaluated demographic data, postoperative short-term outcomes and complications, immunosuppression regime, coronavirus infection status, and behavior during the first phase of the pandemic.
Results: There were no differences between the 2 groups regarding short-term outcomes and postoperative complications or in immunosuppressive medication. After the introduction of intensified hygienic conditions and routine swabs prior to transplantation, no nosocomial SARS-CoV-2 infections occurred. In the outpatient setting, none of the patients developed a SARS-CoV-2 infection. The majority of patients performed voluntary quarantine.
Conclusions: The short-term outcomes after kidney transplantation during the first phase of the coronavirus pandemic were comparable to pre-pandemic patients, and no SARS-CoV-2-associated death or transplant failure occurred in our small cohort. We considered patient compliance with hygiene and self-isolation measures very high. Nevertheless, in further phases of the pandemic, the continuation of the living kidney donation program must be critically evaluated.
MeSH term(s) Adult ; COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19/transmission ; Disease Transmission, Infectious/prevention & control ; Female ; Hospitals/statistics & numerical data ; Humans ; Immunosuppression Therapy/methods ; Infection Control/methods ; Kidney Transplantation/adverse effects ; Kidney Transplantation/statistics & numerical data ; Male ; Middle Aged ; Postoperative Complications/epidemiology ; Postoperative Complications/prevention & control ; Postoperative Complications/virology ; Retrospective Studies ; SARS-CoV-2 ; Treatment Outcome
Language English
Publishing date 2021-01-20
Publishing country United States
Document type Comparative Study ; Journal Article
ZDB-ID 82046-5
ISSN 1873-2623 ; 0041-1345
ISSN (online) 1873-2623
ISSN 0041-1345
DOI 10.1016/j.transproceed.2021.01.036
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Zs.A 835: Show issues Location:
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ab Jg. 2022: Lesesaal (EG)
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